Yingchun Hou

TL;DR: The results indicate that survivin is one of the key players responsible for the innate chemoresistance of colorectal cancer stem cells and aptamer-mediated targeting of survivin in cancerstem cells in combination with chemotherapeutic drugs constitutes a new avenue to improve treatment outcome in oncologic clinics.

TL;DR: It is believed that controlled intermittent aerobic exercise is beneficial to the healing and discovery of damaged cardiac tissues and their function after MI and inhibit TGFβ pathway via up-regulation to the expression of microRNAs and miR-101a and finally cause a reduced fibrosis and scar formation in cardiac tissue.

TL;DR: In this article, the authors explored the role of inhibition of MDR1 or ABCG2 in sensitizing liver cancer stem cells to doxorubicin, the most frequently used chemotherapeutic agent in treating liver cancer.

TL;DR: An improved protein-SELEX procedure is presented for simplified and highly efficient isolation of aptamers against protein targets, and a simplified sample preparation method for MiSeq-based next-generation sequencing is introduced.

TL;DR: The results indicate that ANXA2 plays an important role to enhance the malignant behaviors of HCC cells, and the enhancement is closely based on its remodeling to cell structures.