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Ylva Hellsten
Researcher at University of Copenhagen
Publications - 233
Citations - 12031
Ylva Hellsten is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Skeletal muscle & Vasodilation. The author has an hindex of 61, co-authored 219 publications receiving 10747 citations. Previous affiliations of Ylva Hellsten include University of Virginia & University of Gothenburg.
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Journal ArticleDOI
Vasodilatory mechanisms in contracting skeletal muscle
Philip S. Clifford,Ylva Hellsten +1 more
TL;DR: There is little support for any single vasodilator being essential for exercise hyperemia, and a consensus is beginning to emerge for redundancy among vasodolators, where one vasoactive compound may take over when the formation of another is compromised.
Journal ArticleDOI
Regulation of 5′AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle
Jørgen F. P. Wojtaszewski,Christopher S. MacDonald,Jakob Nielsen,Ylva Hellsten,D. Grahame Hardie,Bruce E. Kemp,Bente Kiens,Erik A. Richter +7 more
TL;DR: It is concluded that muscle AMPK activity and ACCbeta Ser(221) phosphorylation at rest and during exercise are sensitive to the fuel status of the muscle and this dependence may in part be mediated by humoral factors.
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Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA)-riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle.
Jørgen F. P. Wojtaszewski,Sebastian Beck Jørgensen,Ylva Hellsten,D. Grahame Hardie,Erik A. Richter +4 more
TL;DR: It is concluded that acute AICA-riboside treatment leads to phosphorylation and deactivation of glycogen synthase in skeletal muscle and may be a target for AMPK in vivo.
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Effects of α-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle
Sebastian B. Jørgensen,Jørgen F. P. Wojtaszewski,Benoit Viollet,Fabrizio Andreelli,Jesper B. Birk,Ylva Hellsten,Peter Schjerling,Sophie Vaulont,P. Darrell Neufer,Erik A. Richter,Henriette Pilegaard +10 more
TL;DR: KO of the α2 but not the α1‐AMPK isoform markedly diminished AMPK activation during running, and the present data do not support an essential role of AMPK in regulating exercise‐induced gene activation in skeletal muscle.
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Xanthine Oxidase in Human Skeletal Muscle Following Eccentric Exercise: A Role in Inflammation
TL;DR: It is concluded that eccentric exercise leads to an increased level of xanthine oxidase in human muscle and that the increase is associated with secondary inflammatory processes.