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Yongjun Guo
Publications - 19
Citations - 306
Yongjun Guo is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications receiving 221 citations.
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Journal ArticleDOI
Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma
Ling Zhang,Yong Zhou,Caixia Cheng,Heyang Cui,Le Cheng,Pengzhou Kong,Jiaqian Wang,Yin Li,Wenliang Chen,Bin Song,Fang Wang,Zhiwu Jia,Lin Li,Yaoping Li,Bin Yang,Jing Liu,Ruyi Shi,Yanghui Bi,Yanyan Zhang,Juan Wang,Zhenxiang Zhao,Xiaoling Hu,Jie Yang,Hongyi Li,Zhibo Gao,Gang Chen,Xuanlin Huang,Xukui Yang,Shengqing Wan,Chao Chen,Bin Li,Yongkai Tan,Chen Longyun,Minghui He,Sha Xie,Xiangchun Li,Xuehan Zhuang,Mengyao Wang,Zhi Xia,Longhai Luo,Jie Ma,Bing Dong,Jiuzhou Zhao,Yongmei Song,Yunwei Ou,Enming Li,Li-Yan Xu,Jinfen Wang,Yanfeng Xi,Guodong Li,Enwei Xu,Jianfang Liang,Xiaofeng Yang,Jiansheng Guo,Xing Chen,Yanbo Zhang,Qingshan Li,Lixin Liu,Yingrui Li,Xiuqing Zhang,Huanming Yang,Dongxin Lin,Xiaolong Cheng,Yongjun Guo,Jun Wang,Qimin Zhan,Yongping Cui +66 more
TL;DR: High activity of hedgehog signaling and the PI3K pathway in approximately 60% of 104 ESCC tumors indicates that therapies targeting these pathways might be particularly promising strategies for ESCC.
Journal ArticleDOI
Clinicopathologic characteristics and diagnostic methods of RET rearrangement in Chinese non-small cell lung cancer patients
Junnan Feng,Yan Lin,B. Wei,Lei Guo,Weihua Lai,Qingxin Xia,Chen Zhao,Jiawen Zheng,Jiuzhou Zhao,Rui Sun,Yongjun Guo,Luka Brcic,Taiki Hakozaki,Jianming Yang,Jie Ma +14 more
TL;DR: Clinical benefit with chemotherapy is different between CCDC6-RET and KIF5B-RET fusion patients, optimal treatment should be considered when selecting therapies for patients with RET-rearranged lung cancers.
Journal ArticleDOI
MiRNA-363-3p/DUSP10/JNK axis mediates chemoresistance by enhancing DNA damage repair in diffuse large B-cell lymphoma
Wenping Zhou,Yuanlin Xu,Jiuyang Zhang,Peipei Zhang,Zhihua Yao,Zheng Yan,Haiying Wang,Junfeng Chu,Shuna Yao,Shuang Zhao,Shujun Wang,Yongjun Guo,Jinxin Miao,Kangdong Liu,Wing C. Chan,Qingxin Xia,Yanyan Liu +16 more
TL;DR: In this article , the miRNA-363-3p/DUSP10/JNK axis was found to be a novel chemoresistance mechanism in diffuse large B-cell lymphoma (DLBCL).
Journal ArticleDOI
EOAI, a ubiquitin-specific peptidase 5 inhibitor, prevents non-small cell lung cancer progression by inducing DNA damage
TL;DR: In this paper , the effect and mechanism of pan-DUB inhibitor EOAI on non-small cell lung cancer (NSCLC) remains to be studied by immunohistochemistry.
Journal ArticleDOI
Genetic Surveillance of Five SARS-CoV-2 Clinical Samples in Henan Province Using Nanopore Sequencing
Yanan Wang,Duo Chen,Chao Zhu,Zhenhua Zhao,Shanshan Gao,Jianjun Gou,Yongjun Guo,Xiangdong Kong +7 more
TL;DR: This study established a nanopore sequencing platform for genetic surveillance of SARS-CoV-2 and identified the variants circulating in Zhengzhou during August 2021, providing crucial support for government policymaking and prevention and control of COVID-19.