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Shengqing Wan
Researcher at Shanghai Jiao Tong University
Publications - 12
Citations - 2690
Shengqing Wan is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Bladder cancer & Gene. The author has an hindex of 10, co-authored 11 publications receiving 2322 citations. Previous affiliations of Shengqing Wan include Beijing Institute of Genomics.
Papers
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Journal ArticleDOI
Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations
Yanan Cao,Lin Li,Zhimin Feng,Shengqing Wan,Peide Huang,Xiaohui Sun,Fang Wen,Xuanlin Huang,Guang Ning,Weiqing Wang +9 more
TL;DR: Communities and local governments across the country face a period of extreme uncertainty Whether or not COVID-19 is quickly contained, changes in consumer habits and attitudes to climate change are likely to change.
Journal ArticleDOI
Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
Yaoting Gui,Guangwu Guo,Yi Huang,Xueda Hu,Aifa Tang,Aifa Tang,Shengjie Gao,Renhua Wu,Chao Chen,Xianxin Li,Liang Zhou,Minghui He,Zesong Li,Zesong Li,Xiaojuan Sun,Wenlong Jia,Jinnong Chen,Shangming Yang,Fangjian Zhou,Xiaokun Zhao,Shengqing Wan,Rui Ye,Chaozhao Liang,Zhisheng Liu,Peide Huang,Chunxiao Liu,Hui Jiang,Yong Wang,Hancheng Zheng,Liang Sun,Xingwang Liu,Zhimao Jiang,Dafei Feng,Jing Chen,Song Wu,Jing Zou,Zhongfu Zhang,Ruilin Yang,Jun Zhao,Congjie Xu,Weihua Yin,Zhichen Guan,Jiongxian Ye,Hong Zhang,Jingxiang Li,Karsten Kristiansen,Michael L. Nickerson,Dan Theodorescu,Yingrui Li,Xiuqing Zhang,Songgang Li,Jian Wang,Huanming Yang,Jun Wang,Zhiming Cai,Zhiming Cai +55 more
TL;DR: The results provide an overview of the genetic basis of TCC and suggest that aberration of chromatin regulation might be a hallmark of bladder cancer.
Journal ArticleDOI
Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation
Guangwu Guo,Xiaojuan Sun,Chao Chen,Song Wu,Peide Huang,Zesong Li,Michael Dean,Yi Huang,Wenlong Jia,Quan Zhou,Aifa Tang,Zuoquan Yang,Xianxin Li,Pengfei Song,Xiaokun Zhao,Rui Ye,Shiqiang Zhang,Zhao Lin,Mingfu Qi,Shengqing Wan,L F Xie,Fan Fan,Michael L. Nickerson,Xiangjun Zou,Xueda Hu,Li Xing,Zhaojie Lv,Hongbin Mei,Shengjie Gao,Chaozhao Liang,Zhibo Gao,Jingxiao Lu,Yuan Yu,Chunxiao Liu,Lin Li,Xiaodong Fang,Zhimao Jiang,Jie Yang,Cailing Li,Xin Zhao,Jing Chen,Fang Zhang,Yongqi Lai,Zheguang Lin,Fangjian Zhou,Hao Chen,Hsiao Chang Chan,Shirley Tsang,Dan Theodorescu,Yingrui Li,Xiuqing Zhang,Jian Wang,Huanming Yang,Yaoting Gui,Jun Wang,Cai Zhiming +55 more
TL;DR: Analysis of TCC by whole-genome and whole-exome sequencing provides evidence that genetic alterations affecting the SCCS process may be involved in bladder tumorigenesis and identifies a new therapeutic possibility for bladder cancer.
Journal ArticleDOI
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma
Guangwu Guo,Yaoting Gui,Shengjie Gao,Aifa Tang,Aifa Tang,Xueda Hu,Yi Huang,Yi Huang,Wenlong Jia,Zesong Li,Zesong Li,Minghui He,Liang Sun,Pengfei Song,Xiaojuan Sun,Xiaokun Zhao,Sangming Yang,Chaozhao Liang,Shengqing Wan,Fangjian Zhou,Chao Chen,Jialou Zhu,Xianxin Li,Minghan Jian,Liang Zhou,Rui Ye,Peide Huang,Jing Chen,Tao Jiang,Xiao Liu,Yong Wang,Jing Zou,Zhimao Jiang,Renhua Wu,Song Wu,Fan Fan,Zhongfu Zhang,Lin Liu,Ruilin Yang,Xingwang Liu,Haibo Wu,Weihua Yin,Xia Zhao,Yuchen Liu,Huanhuan Peng,Bing-Hua Jiang,Qingxin Feng,Cailing Li,Jun Xie,Jingxiao Lu,Karsten Kristiansen,Yingrui Li,Xiuqing Zhang,Songgang Li,Jian Wang,Huanming Yang,Zhiming Cai,Zhiming Cai,Jun Wang +58 more
TL;DR: These findings highlight the potential contribution of UMPP to ccRCC tumorigenesis through the activation of the hypoxia regulatory network and detect frequent mutations in the ubiquitin-mediated proteolysis pathway (UMPP).
Journal ArticleDOI
Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma
Ling Zhang,Yong Zhou,Caixia Cheng,Heyang Cui,Le Cheng,Pengzhou Kong,Jiaqian Wang,Yin Li,Wenliang Chen,Bin Song,Fang Wang,Zhiwu Jia,Lin Li,Yaoping Li,Bin Yang,Jing Liu,Ruyi Shi,Yanghui Bi,Yanyan Zhang,Juan Wang,Zhenxiang Zhao,Xiaoling Hu,Jie Yang,Hongyi Li,Zhibo Gao,Gang Chen,Xuanlin Huang,Xukui Yang,Shengqing Wan,Chao Chen,Bin Li,Yongkai Tan,Chen Longyun,Minghui He,Sha Xie,Xiangchun Li,Xuehan Zhuang,Mengyao Wang,Zhi Xia,Longhai Luo,Jie Ma,Bing Dong,Jiuzhou Zhao,Yongmei Song,Yunwei Ou,Enming Li,Li-Yan Xu,Jinfen Wang,Yanfeng Xi,Guodong Li,Enwei Xu,Jianfang Liang,Xiaofeng Yang,Jiansheng Guo,Xing Chen,Yanbo Zhang,Qingshan Li,Lixin Liu,Yingrui Li,Xiuqing Zhang,Huanming Yang,Dongxin Lin,Xiaolong Cheng,Yongjun Guo,Jun Wang,Qimin Zhan,Yongping Cui +66 more
TL;DR: High activity of hedgehog signaling and the PI3K pathway in approximately 60% of 104 ESCC tumors indicates that therapies targeting these pathways might be particularly promising strategies for ESCC.