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Yoon Keun Kim
Researcher at Ewha Womans University
Publications - 91
Citations - 3802
Yoon Keun Kim is an academic researcher from Ewha Womans University. The author has contributed to research in topics: Asthma & Mite. The author has an hindex of 27, co-authored 91 publications receiving 3445 citations. Previous affiliations of Yoon Keun Kim include Seoul National University Bundang Hospital & Ajou University.
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Journal ArticleDOI
Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung.
Sun Young Oh,Tao Zheng,Monica L. Bailey,Dwayne L. Barber,John T. Schroeder,Yoon Keun Kim,Zhou Zhu +6 more
TL;DR: Findings provide strong evidence that mice lacking SHIP-1 have an allergic inflammation in the lung, suggesting that SHIP -1 plays an important role in regulating the T(H)2 signaling pathway and in maintaining lung homeostasis.
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The microbiome of the lung and its extracellular vesicles in nonsmokers, healthy smokers and COPD patients.
Hyun-Jung Kim,Hyun-Jung Kim,You-Sun Kim,Kang-Hyun Kim,Jun-Pyo Choi,Yoon Keun Kim,Sunmi Yun,Lokesh Sharma,Charles S. Dela Cruz,Jae Seung Lee,Yeon-Mok Oh,Sang Do Lee,Sei Won Lee +12 more
TL;DR: The analysis of the lung microbiome revealed that the bacterial communities present in the EVs and in the COPD group possessed distinct characteristics with differences in the OTUs, diversity indexes and PCA clustering.
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STAT4 Expression in Human T Cells Is Regulated by DNA Methylation but Not by Promoter Polymorphism
Hyun-Jin Shin,Hye Young Park,Sook Jung Jeong,Heung-Woo Park,Yoon Keun Kim,Sang Heon Cho,You Young Kim,Mi La Cho,Ho-Youn Kim,Kyung Up Min,Chang-Woo Lee +10 more
TL;DR: Interestingly, STAT4 expression was drastically increased in human T cells following treatment with a DNA methyltransferase inhibitor, and truncation of methylation sites in the proximal regulatory elements of the STAT4 promoter markedly enhanced transcriptional activity.
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16S rRNA gene-based metagenomic analysis reveals differences in bacteria-derived extracellular vesicles in the urine of pregnant and non-pregnant women
Jae Young Yoo,Mina Rho,Young Ah You,Eun Jin Kwon,Min Hye Kim,Sungmin Kym,Young Koo Jee,Yoon Keun Kim,Young Ju Kim +8 more
TL;DR: Evaluating whether bacteria-derived EVs are excreted via the urinary tract and comparing the composition of bacteria- derived EVs in the urine of pregnant and non-pregnant women suggested that EVs might have an important role in the maintenance of pregnancy.
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Extracellular Vesicles Derived from Gram-Negative Bacteria, such as Escherichia coli, Induce Emphysema Mainly via IL-17A–Mediated Neutrophilic Inflammation
You-Sun Kim,Won Hee Lee,Eun-Jeong Choi,Jun-Pyo Choi,Young Joo Heo,Yong Song Gho,Young Koo Jee,Yeon-Mok Oh,Yoon Keun Kim +8 more
TL;DR: It is shown that indoor dust from a bed mattress harbors E. coli EVs, which induce IL-17A–dependent neutrophilic inflammation and thereby emphysema, possibly via upregulation of elastase activity.