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Yoonjin Lee
Researcher at Ewha Womans University
Publications - 190
Citations - 3323
Yoonjin Lee is an academic researcher from Ewha Womans University. The author has contributed to research in topics: Apoptosis & Linear code. The author has an hindex of 29, co-authored 172 publications receiving 2749 citations. Previous affiliations of Yoonjin Lee include Smith College & Simon Fraser University.
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Journal ArticleDOI
Axial ligand tuning of a nonheme iron(IV)–oxo unit for hydrogen atom abstraction
Chivukula V. Sastri,Jimin Lee,Kyungeun Oh,Yoonjin Lee,Jung-Hyun Lee,Timothy A. Jackson,Kallol Ray,Hajime Hirao,Woonsup Shin,Jason A. Halfen,Jinheung Kim,Lawrence Que,Sason Shaik,Wonwoo Nam +13 more
TL;DR: A good correlation was observed between the reactivities of iron(IV)–oxo species in H atom abstraction reactions and their reduction potentials, Ep,c, with the most reactive 1′-SR complex exhibiting the lowest potential.
Journal ArticleDOI
Tumor-associated macrophages enhance tumor hypoxia and aerobic glycolysis
Hoibin Jeong,Sehui Kim,Beom-Ju Hong,Chan-Ju Lee,Young Eun Kim,Seoyeon Bok,Jung-Min Oh,Seung-Hee Gwak,Min Young Yoo,Min Sun Lee,Seock-Jin Chung,Joan Defrêne,Philippe A. Tessier,Martin Pelletier,Hyeongrin Jeon,Tae-Young Roh,Bumju Kim,Ki Hean Kim,Ji Hyeon Ju,Sungjee Kim,Yoonjin Lee,Dong Wan Kim,Il Han Kim,Hak Jae Kim,Jong Wan Park,Yun Sang Lee,Jae Sung Lee,Gi Jeong Cheon,Irving L. Weissman,Doo Hyun Chung,Yoon Kyung Jeon,G-One Ahn +31 more
TL;DR: It is demonstrated that tumor-associated macrophages can significantly modulate tumor metabolism, hindering the efficacy of anticancer therapies, including anti-PD-L1 immunotherapy.
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Oxidative stress-induced apoptosis is mediated by ERK1/2 phosphorylation.
Yoonjin Lee,Hae-Nyun Cho,Jae-Won Soh,Gil Ja Jhon,Chul-Koo Cho,Hee-Yong Chung,Sangwoo Bae,Su Jae Lee,Yun Sil Lee +8 more
TL;DR: It is suggested for the first time that oxidative damage-induced apoptosis is mediated by ERK1/2 phosphorylation which is not only Ras-Raf dependent, but also both tyrosine kinase and PKCdelta dependent.
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A Hypoxia-Induced Vascular Endothelial-to-Mesenchymal Transition in Development of Radiation-Induced Pulmonary Fibrosis.
Seo Hyun Choi,Zhen Yu Hong,Jae Kyung Nam,Hae June Lee,Junho Jang,Ran Ji Yoo,Yong Jin Lee,Chang Young Lee,Kyung Hwan Kim,Seung Woo Park,Young Hoon Ji,Yun Sil Lee,Jaeho Cho,Yoonjin Lee +13 more
TL;DR: The first evidence that an EndMT occurs in RIPF development is provided and that the EndMT may be effectively inhibited by modulating vascular EC-specific hypoxic damage.
Journal ArticleDOI
Indirect Tumor Cell Death After High-Dose Hypofractionated Irradiation: Implications for Stereotactic Body Radiation Therapy and Stereotactic Radiation Surgery
Chang W. Song,Yoonjin Lee,Robert J. Griffin,Inhwan Park,Nathan A. Koonce,Susanta K. Hui,Mi-Sook Kim,Kathryn E. Dusenbery,Paul W. Sperduto,L. Chinsoo Cho +9 more
TL;DR: Irradiation of FSaII tumors with 15 to 30 Gy in a single dose caused dose-dependent secondary cell death, most likely by causing vascular damage accompanied by deterioration of intratumor microenvironment, which may play a crucial role in the control of human tumors with SBRT and SRS.