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Yoshibumi Nakane

Researcher at Nagasaki University

Publications -  95
Citations -  3760

Yoshibumi Nakane is an academic researcher from Nagasaki University. The author has contributed to research in topics: Mental health & Schizophrenia. The author has an hindex of 30, co-authored 95 publications receiving 3570 citations. Previous affiliations of Yoshibumi Nakane include Nagasaki International University.

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Congenital malformations due to antiepileptic drugs

TL;DR: The results indicate that the increased incidence of congenital malformations was caused primarily by AEDs, suggesting that mal Formations can be prevented by improvements in drug regimen, and by avoiding polypharmacy and high levels of VPA in the treatment of epileptic women of childbearimg age.
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Teratogenicity of antiepileptic drugs: analysis of possible risk factors.

TL;DR: VPA polypharmacy produced the highest incidence of malformation, higher than that produced by any other AED or drug combination, and Wilcoxon rank‐sum test revealed significant association between the drug score, valproate (VPA), and congenital malformation.