Y
Yoshihiro Ishibashi
Researcher at Takeda Pharmaceutical Company
Publications - 38
Citations - 3365
Yoshihiro Ishibashi is an academic researcher from Takeda Pharmaceutical Company. The author has contributed to research in topics: Peptide sequence & Peptide. The author has an hindex of 21, co-authored 38 publications receiving 3183 citations.
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Journal ArticleDOI
Simultaneous stereoinversion and isomerization at specific aspartic acid residues in alpha A-crystallin from human lens.
TL;DR: The stereoconfiguration of the Asp151 and Asp58 residues in alpha A-crystallin from old subjects was inverted to the D-isomer, and the residues were simultaneously isomerized to beta-aspartyl residues, thought to be the first observation of stereoinversion of amino acids in protein in vivo.
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Identification of urotensin II-related peptide as the urotensin II-immunoreactive molecule in the rat brain☆☆☆
Tsukasa Sugo,Yuko Murakami,Yukio Shimomura,Mioko Harada,Michiko Abe,Yoshihiro Ishibashi,Chieko Kitada,Nobuyuki Miyajima,Nobuhiro Suzuki,Masaaki Mori,Masahiko Fujino +10 more
TL;DR: URP was found to bind and activate the human or rat UII receptors (GPR14) and showed a hypotensive effect when administered to anesthetized rats, suggesting that URP is the endogenous and functional ligand for UII receptor in the rat and mouse, and possibly in the human.
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Long Amyloid .beta.-Protein Secreted from Wild-Type Human Neuroblastoma IMR-32 Cells
TL;DR: The amount of short and long A beta that are secreted from wild-type human and rodent cells with neuron- or glia-like properties using highly sensitive sandwich-ELISAs that discriminate long A Beta from short A beta showed that long Abeta secreted by all cells constitutes approximately 10% of the total A beta.
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Molecular identification of receptor for pituitary adenylate cyclase activating polypeptide
Tetsuya Ohtaki,Takuya Watanabe,Yoshihiro Ishibashi,Chieko Kitada,Masao Tsuda,Paul E. Gottschall,Akira Arimura,Masahiko Fujino +7 more
TL;DR: The results indicate that bovine brain has a specific PACAP receptor, whose apparent molecular weight is 57 k (substracting the molecular weight of [125I]PACAP27 from 60 k).
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Solution conformation of endothelin determined by nuclear magnetic resonance and distance geometry.
TL;DR: Endothelin; Vasoconstrictor peptide; Three‐dimensional structure; NMR, 1H; Distance geometry