Y
Yoshinori Naoe
Researcher at Nagoya University
Publications - 21
Citations - 2173
Yoshinori Naoe is an academic researcher from Nagoya University. The author has contributed to research in topics: Cytotoxic T cell & T cell. The author has an hindex of 16, co-authored 20 publications receiving 1875 citations.
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Journal ArticleDOI
The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes
Shinya Sakaguchi,Matthias Hombauer,Ivan Bilic,Ivan Bilic,Yoshinori Naoe,Alexandra Schebesta,Ichiro Taniuchi,Wilfried Ellmeier +7 more
TL;DR: It is shown that variegated CD8 expression by loss of Cd8 enhancers was reverted in MAZR-deficient mice, which confirms thatMAZR negatively regulates the Cd 8 loci during the transition to the double-positive (DP) stage.
Journal ArticleDOI
Genomic Signature of the Natural Oncolytic Herpes Simplex Virus HF10 and Its Therapeutic Role in Preclinical and Clinical Trials.
Ibrahim Ragab Eissa,Ibrahim Ragab Eissa,Yoshinori Naoe,Itzel Bustos-Villalobos,Toru Ichinose,Maki Tanaka,Wu Zhiwen,Nobuaki Mukoyama,Taishi Morimoto,Noriyuki Miyajima,Hasegawa Hitoki,Seiji Sumigama,Branko Aleksic,Yasuhiro Kodera,Hideki Kasuya +14 more
TL;DR: This review focuses on HF10 in cancer treatment as monotherapy as well as in combination therapy through a concise description of all preclinical and clinical data and addresses approaches for future directions in HF10 studies as cancer therapy.
Journal ArticleDOI
Beneficial effects of Brazilian propolis on type 2 diabetes in ob/ob mice: Possible involvement of immune cells in mesenteric adipose tissue.
Hiroshi Kitamura,Yoshinori Naoe,Shunsuke Kimura,Tomomi Miyamoto,Shiki Okamoto,Chitoku Toda,Yoshinori Shimamoto,Toshihiko Iwanaga,Ichiro Miyoshi +8 more
TL;DR: The anti-diabetic effects of Brazilian propolis were examined using ob/ob mice and microarray and subsequent gene ontology term analyses suggested that propolis attenuated immune activation in mesenteric adipose tissues.
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Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes
Satoshi Kojo,Hirokazu Tanaka,Takaho A. Endo,Sawako Muroi,Ye Liu,Wooseok Seo,Mari Tenno,Kiyokazu Kakugawa,Yoshinori Naoe,Krutula Nair,Kazuyo Moro,Yoshinori Katsuragi,Akinori Kanai,Toshiya Inaba,Takeshi Egawa,Byrappa Venkatesh,Aki Minoda,Ryo Kominami,Ichiro Taniuchi +18 more
TL;DR: It is shown that a pre-commitment event modulated by the transcription factor, Bcl11b, is required for the proper expression of ThPOK and Runx3 and correct CD4/CD8 lineage commitment.
Journal ArticleDOI
Ubiquitin-specific protease 2-69 in macrophages potentially modulates metainflammation
Hiroshi Kitamura,Shunsuke Kimura,Yoshinori Shimamoto,Jun Okabe,Masatoshi Ito,Tomomi Miyamoto,Yoshinori Naoe,Chisato Kikuguchi,Bob Meek,Chitoku Toda,Shiki Okamoto,Katsushi Kanehira,Koji Hase,Hiroshi Watarai,Mayumi Ishizuka,Assam El-Osta,Osamu Ohara,Ichiro Miyoshi +17 more
TL;DR: The results suggest that USP2‐69 suppresses meta‐inflammatory molecules involved in the development of type‐2 diabetes.