Hirokazu Tanaka

TL;DR: In this article, the authors demonstrate that inhibition of RAGE-amphoterin interaction suppressed activation of p44/p42, p38 and SAP/JNK MAP kinases; molecular effector mechanisms importantly linked to tumour proliferation, invasion and expression of matrix metalloproteinases.

TL;DR: STAT5, in addition to ras signaling, appears to mediate transcriptional regulation of cyclin D1, thereby contributing to cytokine‐dependent growth of hematopoietic cells.

TL;DR: A fundamental role for clathrin function in cell polarity, growth, patterning, and organogenesis in plants is demonstrated in plants by genetic means.

TL;DR: Results indicate that E2F1 promotes apoptosis by inhibiting NF-kappaB activity and thereby enhances serum-deprived apoptosis in NIH3T3 and Saos-2.

TL;DR: It is shown that cytokinin regulates endocytic recycling of the auxin efflux carrier PINFORMED1 (PIN1) by redirecting it for lytic degradation in vacuoles, and Stimulation of the lytic PIN1 degradation is not a default effect for general downregulation of proteins from plasma membranes, but a specific mechanism to rapidly modulate the Auxin distribution in cytokinIn-mediated developmental processes.