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Yoshio Okada
Researcher at Osaka University
Publications - 102
Citations - 5455
Yoshio Okada is an academic researcher from Osaka University. The author has contributed to research in topics: Sendai virus & Cell fusion. The author has an hindex of 39, co-authored 101 publications receiving 5373 citations. Previous affiliations of Yoshio Okada include Public Health Research Institute & National Institute for Basic Biology, Japan.
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Journal ArticleDOI
One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell.
TL;DR: Erythrocyte ghosts containing a known number of molecules of purified fragment A of diphtheria toxin with a constant amount of FITC-BSA as a fluorescence marker demonstrated that a single molecule of fragment A was sufficient to kill a cell.
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Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain
Kiyoji Tanaka,Naoyuki Miura,Ichiro Satokata,Iwai Miyamoto,Michihiro C. Yoshida,Yoshiaki Satoh,Seiji Kondo,Akira Yasui,Hiroto Okayama,Yoshio Okada +9 more
TL;DR: Molecular cloning of human and mouse XPAC complementary DNAs indicates that a defective XPAC gene causes group A XP, and expresses ultraviolet-resistance on several group A cell lines, but not on lines of other XP groups.
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High incidence of ultraviolet-B-or chemical-carcinogen-induced skin tumours in mice lacking the xeroderma pigmentosum group A gene
Hironobu Nakane,Seiji Takeuchi,Shunsuke Yuba,Masafumi Saijo,Yoshimichi Nakatsu,Hiroaki Murai,Yoko Nakatsuru,Takatoshi Ishikawa,Seiichi Hirota,Yukihiko Kitamura,Yoko Kato,Yukio Tsunoda,Hiroko Miyauchi,Takeshi Horio,Tomoyuki Tokunaga,Tsukasa Matsunaga,Osamu Nikaido,Yoshitake Nishimune,Yoshio Okada,Kiyoji Tanaka +19 more
TL;DR: In vivo evidence is provided that the XPA protein protects mice from carcinogenesis initiated by ultraviolet or chemical carcinogen, and may provide a good in vivo model to study the high incidence of skin carcinogenesis in group A XP patients.
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Analysis of giant polynuclear cell formation caused by HVJ virus from Ehrlich's ascites tumor cells. I. Microscopic observation of giant polynuclear cell formation.
TL;DR: Two characteristic regions were observed in the reacting cells; one may be a part of the enfolded cell surface, and the other is a complexed projection on the cell surface at the contact point of opposed cells.
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Expression of hepatitis B virus surface antigen in adult rat liver. Co-introduction of DNA and nuclear protein by a simplified liposome method.
TL;DR: A simple and efficient method for gene transfer in vitro (to cultured cells) and in vivo (to an adult organ) using liposomes is established.