CA : A Cancer Journal for Clinicians

Objective To address terminology and other issues related to thyroid fine-needle aspiration (FNA), the National Cancer Institute (NCI) hosted The NCI Thyroid FNA State of the Science Conference. The conclusions regarding terminology and morphologic criteria from the NCI meeting led to the Bethesda Thyroid Atlas Project and form the framework for the Bethesda System for Reporting Thyroid Cytopathology. Design Participants of the Atlas Project were selected from among the committee members of the NCI FNA State of the Science Conference and other participants at the live conference. The terminology framework was based on a literature search of English language publications dating back to 1995 using PubMed as the search engine; online forum discussions ( http://thyroidfna.cancer.gov/forums/default.aspx ); and formal interdisciplinary discussions held on October 22 and 23, 2007, in Bethesda, MD. Main outcome For clarity of communication, the Bethesda System for Reporting Thyroid Cytopathology recommends that each report begin with one of the six general diagnostic categories. Each of the categories has an implied cancer risk that links it to an appropriate clinical management guideline. Conclusions The project participants hope that the adoption of this framework will facilitate communication among cytopathologists, endocrinologists, surgeons, and radiologists; facilitate cytologic-histologic correlation for thyroid diseases; facilitate research into the understanding of thyroid diseases; and allow easy and reliable sharing of data from different laboratories for national and international collaborative studies.

The Bethesda System for Reporting Thyroid Cytopathology.

Summary Background Compared with open resection, laparoscopic resection of rectal cancers is associated with improved short-term outcomes, but high-level evidence showing similar long-term outcomes is scarce. We aimed to compare survival outcomes of laparoscopic surgery with open surgery for patients with mid-rectal or low-rectal cancer. Methods The Comparison of Open versus laparoscopic surgery for mid or low REctal cancer After Neoadjuvant chemoradiotherapy (COREAN) trial was an open-label, non-inferiority, randomised controlled trial done between April 4, 2006, and Aug 26, 2009, at three centres in Korea. Patients (aged 18–80 years) with cT3N0–2M0 mid-rectal or low-rectal cancer who had received preoperative chemoradiotherapy were randomly assigned (1:1) to receive either open or laparoscopic surgery. Randomisation was stratified by sex and preoperative chemotherapy regimen. Investigators were masked to the randomisation sequence; patients and clinicians were not masked to the treatment assignments. The primary endpoint was 3 year disease-free survival, with a non-inferiority margin of 15%. Analysis was by intention to treat. This trial is registered with ClinicalTrials.gov, number NCT00470951. Findings We randomly assigned 340 patients to receive either open surgery (n=170) or laparoscopic surgery (n=170). 3 year disease-free survival was 72·5% (95% CI 65·0–78·6) for the open surgery group and 79·2% (72·3–84·6) for the laparoscopic surgery group, with a difference that was lower than the prespecified non-inferiority margin (–6·7%, 95% CI −15·8 to 2·4; p Interpretation Our results show that laparoscopic resection for locally advanced rectal cancer after preoperative chemoradiotherapy provides similar outcomes for disease-free survival as open resection, thus justifying its use. Funding National Cancer Center, South Korea.

https://www.thelancet.com/pdfs/journals/lanonc/PIIS1470-2045(14)70205-0.pdf

Open versus laparoscopic surgery for mid-rectal or low-rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): survival outcomes of an open-label, non-inferiority, randomised controlled trial.

Objective:To determine the safety of laparoscopy-assisted distal gastrectomy (LADG) compared with open distal gastrectomy (ODG) in patients with clinical stage I gastric cancer in Korea.Background:There is still a lack of large-scale, multicenter randomized trials regarding the safety of LADG.Method

/pdf/decreased-morbidity-of-laparoscopic-distal-gastrectomy-4wpqxuemft.pdf

Decreased Morbidity of Laparoscopic Distal Gastrectomy Compared With Open Distal Gastrectomy for Stage I Gastric Cancer: Short-term Outcomes From a Multicenter Randomized Controlled Trial (KLASS-01).

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The Foundations Of Differential Geometry

Some generalized maximum principles and their applications to chern type problems

In this paper we investigate the kinematic formulas for submanifolds in real space forms, and we give explicit expressions of the kinematic formulas for integral invariants defined by invariant homogeneous polynomials of degree two on second fundamental forms in the sense of Howard, completely. They are actually certain extensions of the Chern-Federer kinematic formula and of the one by Chen.

Kinematic formulas for integral invariants of degree two in real space forms

First we introduce a new notion of generalized Killing Ricci tensor which is equivalent to the notion of cyclic parallel Ricci tensor for real hypersurfaces in the complex quadric Qm=SOm+2/SOmSO2$Q^m = SO_{m+2}/SO_mSO_2$ . Next, in terms of A$\mathfrak {A}$ ‐principal or A$\mathfrak {A}$ ‐isotropic unit normal vector fields we give a complete classification of real hypersurfaces in Qm=SOm+2/SOmSO2$Q^m = SO_{m+2}/SO_mSO_2$ with cyclic parallel Ricci tensor.

Generalized Killing Ricci tensor for real hypersurfaces in the complex quadric

Harmonic curvature for real hypersurfaces in complex hyperbolic two plane Grassmannians

https://ir.ymlib.yonsei.ac.kr/bitstream/22282913/181441/1/T202005722.pdf

Young Jin Suh

Papers

Some generalized maximum principles and their applications to chern type problems

Kinematic formulas for integral invariants of degree two in real space forms

Generalized Killing Ricci tensor for real hypersurfaces in the complex quadric

Harmonic curvature for real hypersurfaces in complex hyperbolic two plane Grassmannians

A nationwide, multicenter retrospective study on the effectiveness and safety of eribulin in Korean breast cancer patients (REMARK).