CA : A Cancer Journal for Clinicians

Objective To address terminology and other issues related to thyroid fine-needle aspiration (FNA), the National Cancer Institute (NCI) hosted The NCI Thyroid FNA State of the Science Conference. The conclusions regarding terminology and morphologic criteria from the NCI meeting led to the Bethesda Thyroid Atlas Project and form the framework for the Bethesda System for Reporting Thyroid Cytopathology. Design Participants of the Atlas Project were selected from among the committee members of the NCI FNA State of the Science Conference and other participants at the live conference. The terminology framework was based on a literature search of English language publications dating back to 1995 using PubMed as the search engine; online forum discussions ( http://thyroidfna.cancer.gov/forums/default.aspx ); and formal interdisciplinary discussions held on October 22 and 23, 2007, in Bethesda, MD. Main outcome For clarity of communication, the Bethesda System for Reporting Thyroid Cytopathology recommends that each report begin with one of the six general diagnostic categories. Each of the categories has an implied cancer risk that links it to an appropriate clinical management guideline. Conclusions The project participants hope that the adoption of this framework will facilitate communication among cytopathologists, endocrinologists, surgeons, and radiologists; facilitate cytologic-histologic correlation for thyroid diseases; facilitate research into the understanding of thyroid diseases; and allow easy and reliable sharing of data from different laboratories for national and international collaborative studies.

The Bethesda System for Reporting Thyroid Cytopathology.

Summary Background Compared with open resection, laparoscopic resection of rectal cancers is associated with improved short-term outcomes, but high-level evidence showing similar long-term outcomes is scarce. We aimed to compare survival outcomes of laparoscopic surgery with open surgery for patients with mid-rectal or low-rectal cancer. Methods The Comparison of Open versus laparoscopic surgery for mid or low REctal cancer After Neoadjuvant chemoradiotherapy (COREAN) trial was an open-label, non-inferiority, randomised controlled trial done between April 4, 2006, and Aug 26, 2009, at three centres in Korea. Patients (aged 18–80 years) with cT3N0–2M0 mid-rectal or low-rectal cancer who had received preoperative chemoradiotherapy were randomly assigned (1:1) to receive either open or laparoscopic surgery. Randomisation was stratified by sex and preoperative chemotherapy regimen. Investigators were masked to the randomisation sequence; patients and clinicians were not masked to the treatment assignments. The primary endpoint was 3 year disease-free survival, with a non-inferiority margin of 15%. Analysis was by intention to treat. This trial is registered with ClinicalTrials.gov, number NCT00470951. Findings We randomly assigned 340 patients to receive either open surgery (n=170) or laparoscopic surgery (n=170). 3 year disease-free survival was 72·5% (95% CI 65·0–78·6) for the open surgery group and 79·2% (72·3–84·6) for the laparoscopic surgery group, with a difference that was lower than the prespecified non-inferiority margin (–6·7%, 95% CI −15·8 to 2·4; p Interpretation Our results show that laparoscopic resection for locally advanced rectal cancer after preoperative chemoradiotherapy provides similar outcomes for disease-free survival as open resection, thus justifying its use. Funding National Cancer Center, South Korea.

https://www.thelancet.com/pdfs/journals/lanonc/PIIS1470-2045(14)70205-0.pdf

Open versus laparoscopic surgery for mid-rectal or low-rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): survival outcomes of an open-label, non-inferiority, randomised controlled trial.

Objective:To determine the safety of laparoscopy-assisted distal gastrectomy (LADG) compared with open distal gastrectomy (ODG) in patients with clinical stage I gastric cancer in Korea.Background:There is still a lack of large-scale, multicenter randomized trials regarding the safety of LADG.Method

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Decreased Morbidity of Laparoscopic Distal Gastrectomy Compared With Open Distal Gastrectomy for Stage I Gastric Cancer: Short-term Outcomes From a Multicenter Randomized Controlled Trial (KLASS-01).

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The Foundations Of Differential Geometry

In this paper, first, we investigate the commuting property between the normal Jacobi operator ${\bar R}_{N}$
 and the structure Jacobi operator Rξ for Hopf real hypersurfaces in the complex quadric Qm = SOm+ 2/SOmSO2 for $m \geqslant 3$
 , which is defined by ${\bar R}_{N} R_{\xi } = R_{\xi }{\bar R}_{N}$
 . Moreover, a new characterization of Hopf real hypersurfaces with $\mathfrak A$
 -principal singular normal vector field in the complex quadric Qm is obtained. By virtue of this result, we can give a remarkable classification of Hopf real hypersurfaces in the complex quadric Qm with commuting Jacobi operators.

Commuting Jacobi Operators on Real Hypersurfaces of Type B in the Complex Quadric

We study curvature structures of compact hypersurfaces in the unit sphere Sn+1(1) with two distinct principal curvatures. First of all, we prove that the Riemannian product is the only compact hypersurface in Sn+1(1) with two distinct principal curvatures, one of which is simple and satisfies where n(n − 1)r is the scalar curvature of hypersurfaces and c2 = (n − 2)/nr. This generalized the result of Cheng, where the scalar curvature is constant is assumed. Secondly, we prove that the Riemannian product is the only compact hypersurface with non-zero mean curvature in Sn+1(1) with two distinct principal curvatures, one of which is simple and satisfies This gives a partial answer for the problem proposed by Cheng.

https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0308210500004303

Compact hypersurfaces in a unit sphere

The object of the present paper is to study weakly cyclic Z symmetric manifolds. Some geometric properties have been studied. We obtain a sufficient condition for a weakly cyclic Z symmetric manifold to be a quasi Einstein manifold. Next we consider conformally flat weakly cyclic Z symmetric manifolds. Then we study Einstein (WCZS)
 n
 (n > 2). Also we study decomposable (WCZS)
 n
 (n > 2). We prove the equivalency of semisymmetry and Weyl-semisymmetry in a (WCZS)
 n
 (n > 2). Finally, we give an example of a (WCZS)4.

On weakly cyclic Z symmetric manifolds

In this article, using the example of C. Camci((7)) we reconrm necessary suf- �cient condition for a slant curve. Next, wend some necessary and sufficient conditions for a slant curve in a Sasakian 3-manifold to have: (i) a C-parallel mean curvature vector

/pdf/c-parallel-mean-curvature-vector-fields-along-slant-curves-5gsjh2fbqx.pdf

C-parallel mean curvature vector fields along slant curves in Sasakian 3-manifolds

In this paper, we characterize the gradient Yamabe and the gradient m-quasi Einstein solitons within the framework of three-dimensional cosymplectic manifolds.

Young Jin Suh

Papers

Commuting Jacobi Operators on Real Hypersurfaces of Type B in the Complex Quadric

Compact hypersurfaces in a unit sphere

On weakly cyclic Z symmetric manifolds

C-parallel mean curvature vector fields along slant curves in Sasakian 3-manifolds

Gradient Yamabe and Gradient m-Quasi Einstein Metrics on Three-dimensional Cosymplectic Manifolds