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Yu Huang
Researcher at University of Texas Health Science Center at Houston
Publications - 19
Citations - 1075
Yu Huang is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Dielectrophoresis & Context (archaeology). The author has an hindex of 11, co-authored 14 publications receiving 953 citations. Previous affiliations of Yu Huang include Chinese Academy of Sciences & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
Introducing dielectrophoresis as a new force field for field-flow fractionation.
TL;DR: The validity of the model is demonstrated with human leukemia (HL-60) cells subjected to a parallel electrode array, and application of the device to separating HL-60 cells from peripheral blood mononuclear cells is shown.
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Dielectrophoretic manipulation of cells with spiral electrodes
TL;DR: It was shown that the conventional and traveling-wave dielectrophoretic force components dominated cell levitation and radial motion, respectively, and the cell radial velocity was very sensitive to the field frequency when the in-phase component of the field-induced polarization was close to zero.
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Extracellular Spermine Exacerbates Ischemic Neuronal Injury through Sensitization of ASIC1a Channels to Extracellular Acidosis
Bo Duan,Yi Zhi Wang,Tao Yang,Xiang-Ping Chu,Ye Yu,Yu Huang,Hui Cao,Jillian C. Hansen,Roger P. Simon,Michael X. Zhu,Zhi-Gang Xiong,Tian Le Xu +11 more
TL;DR: It is shown that extracellular spermine contributes significantly to ischemic neuronal injury through enhancing ASIC1a activity, and suggests new neuroprotective strategies for stroke patients via inhibition of polyamine synthesis and subsequent s permine–ASIC interaction.
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Tissue acidosis induces neuronal necroptosis via ASIC1a channel independent of its ionic conduction
Yi Zhi Wang,Wang Jingjing,Yu Huang,Fan Liu,Wei-Zheng Zeng,Ying Li,Zhi-Gang Xiong,Michael X. Zhu,Tian Le Xu +8 more
TL;DR: It is shown that extracellular protons function as a novel endogenous ligand that triggers neuronal necroptosis during ischemia via ASIC1a, but independent of its ion-conducting function.
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PI3-kinase/Akt Pathway-Regulated Membrane Insertion of Acid-Sensing Ion Channel 1a Underlies BDNF-Induced Pain Hypersensitivity
Bo Duan,Di Shi Liu,Yu Huang,Wei-Zheng Zeng,Xiang Wang,Hui Yu,Michael X. Zhu,Zhe Yu Chen,Tian Le Xu +8 more
TL;DR: It is shown that deletion of ASIC1 gene suppressed the sustained mechanical hyperalgesia induced by intrathecal BDNF application in mice, revealing a novel mechanism underlying central sensitization and pain hypersensitivity, and reinforcing the critical role of ASIC 1a channels in these processes.