Liping Qiu

TL;DR: This programmable cascade reaction presents a simple and modular amplification mechanism for intracellular biomarkers of interest, providing a significant boost to the search for clues leading to the accurate identification and effective treatment of cancers.

TL;DR: A multifunctional aptamer-based DNA nanoassembly structure able to take advantage of facile modular design and assembly, high programmability, excellent biostability and biocompatibility, as well as selective recognition and transportation shows promise as candidates for targeted drug delivery and cancer therapy.

TL;DR: This work has used DNA self-assembly to develop a nuclear-uptake nanodrug system carried by a cell-targeted near-infrared (NIR)-responsive nanotruck for drug-resistant cancer therapy that can efficiently accumulated in the nuclei to effectively kill the cancer cells.

TL;DR: A novel DNA probe is shown that can transduce transient membrane encounter events into readable cumulative fluorescence signals and show a preference for encounters within the same lipid domains.

TL;DR: A DNA-based device capable of performing autonomous logic-based analysis of multiple cancer cell-surface markers and, in response, producing a diagnostic signal and/or targeted photodynamic therapy, called "Nano-Claw".