Y
Yubin Qiu
Researcher at Millennium Pharmaceuticals
Publications - 7
Citations - 822
Yubin Qiu is an academic researcher from Millennium Pharmaceuticals. The author has contributed to research in topics: Receptor & Transgene. The author has an hindex of 7, co-authored 7 publications receiving 790 citations.
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Journal ArticleDOI
Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism.
Anja Köster,Y. Bernice Chao,Marian Mosior,Amy M. Ford,Patricia Gonzalez-DeWhitt,John E. Hale,De-Shan Li,Yubin Qiu,Christopher C. Fraser,Derek D. Yang,Josef G. Heuer,S. Richard Jaskunas,Patrick I. Eacho +12 more
TL;DR: Angptl3 and Angptl4 function to regulate circulating triglyceride levels during different nutritional states and therefore play a role in lipid metabolism during feeding/fasting through differential inhibition of LPL.
Journal ArticleDOI
Modulation of LIGHT-HVEM costimulation prolongs cardiac allograft survival.
Qunrui Ye,Christopher Fraser,Wei Gao,Liqing Wang,Samantha J. Busfield,Chichung Wang,Yubin Qiu,Anthony J. Coyle,Jose-Carlos Gutierrez-Ramos,Wayne W. Hancock +9 more
TL;DR: The data suggest that T cell to T cell–mediated LIGHT/HVEM-dependent costimulation is a significant component of the host response leading to cardiac allograft rejection.
Journal ArticleDOI
PK1/EG-VEGF induces monocyte differentiation and activation.
Marion Dorsch,Yubin Qiu,Dulce Soler,Nita Frank,Thao Duong,Andrew D. J. Goodearl,Steve O’Neil,Jose M. Lora,Christopher Fraser +8 more
TL;DR: It is demonstrated PK1 induces differentiation of murine and human bone marrow cells into the monocyte/macrophage lineage and induces a distinct monocyte‐derived cell population, which is primed for release of proinflammatory cytokines that favor a T helper cell type 1 response.
Journal ArticleDOI
Coordinated Involvement of Mast Cells and T Cells in Allergic Mucosal Inflammation: Critical Role of the CC Chemokine Ligand 1:CCR8 Axis
Jose-Angel Gonzalo,Yubin Qiu,Jose M. Lora,Amal Al-Garawi,Jean-Luc Villeval,Joshua A. Boyce,Carlos Martínez-A,Gabriel Márquez,Innigo Goya,Qutayba Hamid,Christopher Fraser,Dominic Picarella,Javier Cote-Sierra,Martin R. Hodge,Jose-Carlos Gutierrez-Ramos,Roland Kolbeck,Anthony J. Coyle +16 more
TL;DR: Adenoviral delivery of CCL1 to the lungs of mast cell-deficient mice restores airway hyperresponsiveness, lung inflammation, and mucus hypersecretion to the degree observed in wild-type mice.
Journal ArticleDOI
Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family.
Christopher Fraser,Duncan Howie,Massimo Morra,Yubin Qiu,Curran Murphy,Qiong Shen,Jose-Carlos Gutierrez-Ramos,Anthony J. Coyle,Gillian Kingsbury,Cox Terhorst +9 more
TL;DR: The data suggest that signaling through SF2000, together with CD150, CD244, CD84, and CD229, is controlled by SAP and therefore contributes to the pathogenesis of XLP.