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Yueh Chien
Researcher at Taipei Veterans General Hospital
Publications - 40
Citations - 884
Yueh Chien is an academic researcher from Taipei Veterans General Hospital. The author has contributed to research in topics: Induced pluripotent stem cell & Gene delivery. The author has an hindex of 14, co-authored 39 publications receiving 556 citations. Previous affiliations of Yueh Chien include National Yang-Ming University.
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Journal ArticleDOI
Corneal repair by human corneal keratocyte-reprogrammed iPSCs and amphiphatic carboxymethyl-hexanoyl chitosan hydrogel
Yueh Chien,Yi Wen Liao,Dean-Mo LIu,Heng Liang Lin,Shih Jen Chen,Hen Li Chen,Chi Hsien Peng,Chi Hsien Peng,Chang Min Liang,Chung-Yuan Mou,Shih Hwa Chiou +10 more
TL;DR: It is demonstrated that these human keratocyte-reprogrammed iPSCs, when combined with CHC hydrogel, can be used as a rapid delivery system to efficiently enhance corneal wound healing.
Journal ArticleDOI
Reprogramming induced pluripotent stem cells in the absence of c-Myc for differentiation into hepatocyte-like cells.
Hsin Yang Li,Yueh Chien,Yueh Chien,Yi Jen Chen,Yi Jen Chen,Szu Fu Chen,Yuh Lih Chang,Chih Hung Chiang,Chih Hung Chiang,Shaw Yeu Jeng,Shaw Yeu Jeng,Chia Ming Chang,Chia Ming Chang,Mong Lien Wang,Liang Kung Chen,Liang Kung Chen,Shuen-Iu Hung,Teh Ia Huo,Teh Ia Huo,Shou-Dong Lee,Shih Hwa Chiou +20 more
TL;DR: It is demonstrated that iPSCs without c-Myc had the capacity to differentiate into hepatocyte-like cells (iPSC-Heps) with biological functions and may prevent oxidative stress-induced damage and provide a safer alternative for hepatic regeneration in AHF.
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Morphological and Molecular Defects in Human Three-Dimensional Retinal Organoid Model of X-Linked Juvenile Retinoschisis
Kang Chieh Huang,Kang Chieh Huang,Kang Chieh Huang,Mong Lien Wang,Shih Jen Chen,Shih Jen Chen,Jean Cheng Kuo,Won Jing Wang,Phan Nguyen Nhi Nguyen,Phan Nguyen Nhi Nguyen,Karl J. Wahlin,Jyh Feng Lu,Audrey A. Tran,Michael Shi,Yueh Chien,Aliaksandr A. Yarmishyn,Ping Hsing Tsai,Ping Hsing Tsai,Tien Chun Yang,Tien Chun Yang,Wann-Neng Jane,Chia-Ching Chang,Chi Hsien Peng,Thorsten M. Schlaeger,Shih Hwa Chiou +24 more
TL;DR: 3D organoids are established as a valid disease model for X-linked juvenile retinoschisis and it is shown that the C625T mutation can be repaired precisely and efficiently using a base-editing approach.
Journal ArticleDOI
METTL3-dependent N6-methyladenosine RNA modification mediates the atherogenic inflammatory cascades in vascular endothelium.
Chian Shiu Chien,Julie Yi Shuan Li,Yueh Chien,Yueh Chien,Mong Lien Wang,Mong Lien Wang,Aliaksandr A. Yarmishyn,Aliaksandr A. Yarmishyn,Ping Hsing Tsai,Ping Hsing Tsai,Chi Chang Juan,Phu Nguyen,Hao Min Cheng,Teh Ia Huo,Teh Ia Huo,Shih Hwa Chiou,Shih Hwa Chiou,Shih Hwa Chiou,Shu Chien +18 more
TL;DR: In this paper, the role of N6-methyladenosine (m6A) RNA methylation in mechanotransduction in endothelial cells (ECs) is investigated.
Journal ArticleDOI
Musashi-1 promotes cancer stem cell properties of glioblastoma cells via upregulation of YTHDF1.
Aliaksandr A. Yarmishyn,Aliaksandr A. Yarmishyn,Yi-Ping Yang,Yi-Ping Yang,Kai-Hsi Lu,Yi Chen Chen,Yueh Chien,Shih Jie Chou,Ping-Hsing Tsai,Hsin-I Ma,Chian Shiu Chien,Chian Shiu Chien,Ming-Teh Chen,Ming-Teh Chen,Mong Lien Wang,Mong Lien Wang +15 more
TL;DR: In this paper, the authors investigated the expression of five YTH family proteins in different GBM microarray datasets from the Oncominedatabase, and identified YTHDF1 as the most highly overexpressed member of this family in GBM.