Y
Yuji Kashiwakura
Researcher at Jichi Medical University
Publications - 66
Citations - 2328
Yuji Kashiwakura is an academic researcher from Jichi Medical University. The author has contributed to research in topics: Adeno-associated virus & Tumor suppressor gene. The author has an hindex of 25, co-authored 61 publications receiving 2185 citations. Previous affiliations of Yuji Kashiwakura include Mitsubishi & Juntendo University.
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Journal ArticleDOI
Severe secondary deficiency of von Willebrand factor-cleaving protease (ADAMTS13) in patients with sepsis-induced disseminated intravascular coagulation: its correlation with development of renal failure.
Tomoko Ono,Jun Mimuro,Seiji Madoiwa,Kenji Soejima,Yuji Kashiwakura,Akira Ishiwata,Katsuhiro Takano,Tsukasa Ohmori,Yoichi Sakata +8 more
TL;DR: Deep molecular weight forms of ADAMTS13 were found in the plasma of patients with sepsis-induced DIC, suggesting that the deficiency of ADamTS13 was partially caused by its cleavage by proteases in addition to decreased synthesis in the liver.
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Hepatocyte Growth Factor Receptor Is a Coreceptor for Adeno-Associated Virus Type 2 Infection
Yuji Kashiwakura,Kenji Tamayose,Kazuhisa Iwabuchi,Yukihiko Hirai,Takashi Shimada,Kunio Matsumoto,Toshikazu Nakamura,Masami Watanabe,Kazuo Oshimi,Hiroyuki Daida +9 more
TL;DR: It is demonstrated that hepatocyte growth factor receptor, c-Met, is also a coreceptor for AAV2 infection by facilitating AAV1 internalization into the cytoplasm and the physical interaction between A AV2 and the β subunit of c- met.
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Il2rg Gene-Targeted Severe Combined Immunodeficiency Pigs
Shunichi Suzuki,Masaki Iwamoto,Yoriko Saito,Daiichiro Fuchimoto,Shoichiro Sembon,M. Suzuki,Satoshi Mikawa,Michiko Hashimoto,Yuki Aoki,Yuho Najima,Shinsuke Takagi,Nahoko Suzuki,Emi Suzuki,Masanori Kubo,Jun Mimuro,Yuji Kashiwakura,Seiji Madoiwa,Yoichi Sakata,Anthony C.F. Perry,Fumihiko Ishikawa,Akira Onishi +20 more
TL;DR: The generation and preliminary evaluation of a porcine SCID model of severe combined immunodeficiency pigs represent a step toward the comprehensive evaluation of preclinical cellular regenerative strategies.
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Isolation of Bone Marrow Stromal Cell–Derived Smooth Muscle Cells by a Human SM22α Promoter In Vitro Differentiation of Putative Smooth Muscle Progenitor Cells of Bone Marrow
Yuji Kashiwakura,Youichi Katoh,Kenji Tamayose,Hakuoh Konishi,Norihide Takaya,Senji Yuhara,Masanori Yamada,Koichi Sugimoto,Hiroyuki Daida +8 more
TL;DR: The presence of a cell population fated to become SMCs and followed their differentiation into SMCs among BMSCs is demonstrated.
Journal ArticleDOI
Antagonism of Sphingosine 1-Phosphate Receptor-2 Enhances Migration of Neural Progenitor Cells Toward an Area of Brain Infarction
Atsushi Kimura,Tsukasa Ohmori,Yuji Kashiwakura,Ryunosuke Ohkawa,Seiji Madoiwa,Jun Mimuro,Kuniko Shimazaki,Yuichi Hoshino,Yutaka Yatomi,Yoichi Sakata +9 more
TL;DR: S1P is a chemoattractant for NPCs released from an infarcted area and regulation of S1P2R function further enhances the migration of NPCs toward a brain infarction.