J
Jun Mimuro
Researcher at Jichi Medical University
Publications - 90
Citations - 2791
Jun Mimuro is an academic researcher from Jichi Medical University. The author has contributed to research in topics: Plasminogen activator & Fibrinolysis. The author has an hindex of 26, co-authored 90 publications receiving 2618 citations. Previous affiliations of Jun Mimuro include Mitsubishi.
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Severe secondary deficiency of von Willebrand factor-cleaving protease (ADAMTS13) in patients with sepsis-induced disseminated intravascular coagulation: its correlation with development of renal failure.
Tomoko Ono,Jun Mimuro,Seiji Madoiwa,Kenji Soejima,Yuji Kashiwakura,Akira Ishiwata,Katsuhiro Takano,Tsukasa Ohmori,Yoichi Sakata +8 more
TL;DR: Deep molecular weight forms of ADAMTS13 were found in the plasma of patients with sepsis-induced DIC, suggesting that the deficiency of ADamTS13 was partially caused by its cleavage by proteases in addition to decreased synthesis in the liver.
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Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury.
Atsushi Kimura,Tsukasa Ohmori,Ryunosuke Ohkawa,Seiji Madoiwa,Jun Mimuro,Takashi Murakami,Eiji Kobayashi,Yuichi Hoshino,Yutaka Yatomi,Yoichi Sakata +9 more
TL;DR: It is found that sphingosine 1‐phosphate (Sph‐1‐P), a physiological lysophospholipid mediator, had a potent chemoattractant activity for NSPCs, in which, of Sph‐ 1‐P receptors, S1P1 was abundantly expressed.
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Monoclonal antibodies to discrete regions in alpha 2-plasmin inhibitor
TL;DR: Three monoclonal antibodies to alpha 2-plasmin inhibitor (alpha 2PI) were characterized and results suggested that the antibody recognized an epitope near the N terminus, useful for analyzing the mechanism of interaction between alpha 2PI and plasmin.
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Il2rg Gene-Targeted Severe Combined Immunodeficiency Pigs
Shunichi Suzuki,Masaki Iwamoto,Yoriko Saito,Daiichiro Fuchimoto,Shoichiro Sembon,M. Suzuki,Satoshi Mikawa,Michiko Hashimoto,Yuki Aoki,Yuho Najima,Shinsuke Takagi,Nahoko Suzuki,Emi Suzuki,Masanori Kubo,Jun Mimuro,Yuji Kashiwakura,Seiji Madoiwa,Yoichi Sakata,Anthony C.F. Perry,Fumihiko Ishikawa,Akira Onishi +20 more
TL;DR: The generation and preliminary evaluation of a porcine SCID model of severe combined immunodeficiency pigs represent a step toward the comprehensive evaluation of preclinical cellular regenerative strategies.
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Aspirin resistance detected with aggregometry cannot be explained by cyclooxygenase activity: involvement of other signaling pathway(s) in cardiovascular events of aspirin-treated patients.
Tsukasa Ohmori,Yutaka Yatomi,T. Nonaka,Y. Kobayashi,Seiji Madoiwa,Jun Mimuro,Yukio Ozaki,Yoichi Sakata +7 more
TL;DR: Aspirin resistance expressed as unsuppressed platelet COX‐1 activity is a rare condition in an out‐patient population and the existence of diabetes mellitus was an independent risk factor for overall outcomes.