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Yukio Ishikawa
Researcher at Toho University
Publications - 116
Citations - 5086
Yukio Ishikawa is an academic researcher from Toho University. The author has contributed to research in topics: Lymphatic system & Myocardial bridge. The author has an hindex of 43, co-authored 116 publications receiving 4730 citations. Previous affiliations of Yukio Ishikawa include Osaka University & National Defense Medical College.
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Journal ArticleDOI
Cellular Prostaglandin E2 Production by Membrane-bound Prostaglandin E Synthase-2 via Both Cyclooxygenases-1 and -2
Makoto Murakami,Karin Nakashima,Daisuke Kamei,Seiko Masuda,Yukio Ishikawa,Toshiharu Ishii,Yoshihiro Ohmiya,Kikuko Watanabe,Ichiro Kudo +8 more
TL;DR: In this paper, the expression and functional aspects of the third prostaglandin E synthase, mPGES-2, in mammalian cells and tissues were examined. But, the results showed that the expression was not increased appreciably during tissue inflammation or damage.
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Reduced Pain Hypersensitivity and Inflammation in Mice Lacking Microsomal Prostaglandin E Synthase-1
Daisuke Kamei,Kiyofumi Yamakawa,Yui Takegoshi,Maya Mikami-Nakanishi,Yoshihito Nakatani,Sachiko Oh-ishi,Hidekazu Yasui,Yoshiaki Azuma,Noriyasu Hirasawa,Kazuo Ohuchi,Hiroshi Kawaguchi,Yukio Ishikawa,Toshiharu Ishii,Satoshi Uematsu,Shizuo Akira,Makoto Murakami,Ichiro Kudo +16 more
TL;DR: Evidence is provided that mPGES-1 contributes to the formation of PGE2 involved in pain hypersensitivity and inflammation and collagen antibody-induced arthritis, a model for human rheumatoid arthritis, was milder in KO mice than in WT mice.
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Potential role of microsomal prostaglandin E synthase-1 in tumorigenesis.
TL;DR: Results collectively suggest that aberrant expression of mPGES-1 in combination with COX-2 can contribute to tumorigenesis.
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Expression of ACE and ACE2 in individuals with diabetic kidney disease and healthy controls.
Sonoo Mizuiri,Hiromichi Hemmi,Michitsune Arita,Yasushi Ohashi,Yoshihide Tanaka,Moriatsu Miyagi,Ken Sakai,Yukio Ishikawa,Kazutoshi Shibuya,Hiroki Hase,Atsushi Aikawa +10 more
TL;DR: The high ACE/ACE2 ratio in kidneys of patients with type 2 diabetes with overt nephropathy may contribute to renal injury.
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The effects of a myocardial bridge on coronary atherosclerosis and ischaemia.
TL;DR: Considering the occurrence of myocardial infarction in cases of proximal MB together with previous reports on relationships between MB and coronary ischaemia, it appears that anatomical characteristics such as the location, length, and thickness of the MB have a bearing on the effects of this abnormality.