Z
Z. Reno Vlahcevic
Researcher at Veterans Health Administration
Publications - 4
Citations - 1119
Z. Reno Vlahcevic is an academic researcher from Veterans Health Administration. The author has contributed to research in topics: Reverse cholesterol transport & Placebo. The author has an hindex of 4, co-authored 4 publications receiving 1102 citations. Previous affiliations of Z. Reno Vlahcevic include University of California, San Diego & VCU Medical Center.
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Journal ArticleDOI
Long-term outcome of medical and surgical therapies for gastroesophageal reflux disease: follow-up of a randomized controlled trial.
Stuart J. Spechler,Edward L. Lee,Dennis J. Ahnen,Raj K. Goyal,Ikuo Hirano,Francisco C. Ramirez,Jean-Pierre Raufman,Richard E. Sampliner,Thomas G. Schnell,Stephen J. Sontag,Z. Reno Vlahcevic,Renee Young,William O. Williford +12 more
TL;DR: This study suggests that antireflux surgery should not be advised with the expectation that patients with GERD will no longer need to take antisecretory medications or that the procedure will prevent esophageal cancer among those with GERd and Barrett esophagus.
Journal ArticleDOI
Conjugates of ursodeoxycholate protect against cytotoxicity of more hydrophobic bile salts : in vitro studies in rat hepatocytes and human erythrocytes
Douglas M. Heuman,Douglas M. Heuman,W. Michael Pandak,W. Michael Pandak,Philip B. Hylemon,Z. Reno Vlahcevic,Z. Reno Vlahcevic +6 more
TL;DR: In vivo, ursodeoxycholate may improve cholestatic liver disease by reducing the toxicity of endogenous bile salts at the luminal surface of the canalicular plasma membrane, suggesting that protection does not depend on liver‐specific pathways of bile salt uptake, compartmentation, transport or metabolism.
Journal ArticleDOI
Healing of Benign Gastric Ulcer: Comparison of Cimetidine and Placebo in the United States
David Y. Graham,Kemal Akdamar,Walter P. Dyck,Edwin Englert,Robert G. Strickland,James L. Achord,Alphonso A. Belsito,Z. Reno Vlahcevic,Robert N. Kornfield,William B. Long,Stephen J. Sontag,Naurang M. Agrawal +11 more
TL;DR: Cimetidine treatment resulted in significantly more rapid healing than placebo; after 2 and 6 weeks of therapy, 10.0% and 44.8% of patients receiving placebo were healed, as compared to 22.6% and 65.1% receiving cimetidine.
Journal ArticleDOI
Effect of cholylsarcosine on hepatic cholesterol and bile acid synthesis and bile secretion in rats.
Douglas M. Heuman,Douglas M. Heuman,Douglas M. Heuman,Z. Reno Vlahcevic,Z. Reno Vlahcevic,Z. Reno Vlahcevic,W. Michael Pandak,W. Michael Pandak,W. Michael Pandak,Phillip B. Hylemon,Phillip B. Hylemon,Phillip B. Hylemon,Young S. Kim,Young S. Kim,Young S. Kim,Jan Lillienau,Jan Lillienau,Jan Lillienau,Alan F. Hofmann,Alan F. Hofmann,Alan F. Hofmann +20 more
TL;DR: In the rat, cholyl conjugates per se can suppress cholesterol and bile acid biosynthesis without prior conversion to deoxycholate.