Z
Zafer Ugur
Researcher at Beaumont Health
Publications - 12
Citations - 149
Zafer Ugur is an academic researcher from Beaumont Health. The author has contributed to research in topics: Metabolome & Tauroursodeoxycholic acid. The author has an hindex of 4, co-authored 12 publications receiving 55 citations. Previous affiliations of Zafer Ugur include Beaumont Hospital & Oakland University.
Papers
More filters
Journal ArticleDOI
Metabolomic Profiling of Bile Acids in an Experimental Model of Prodromal Parkinson's Disease.
Stewart F. Graham,Nolwen L. Rey,Zafer Ugur,Ali Yilmaz,Eric Sherman,Michael Maddens,Michael Maddens,Ray O. Bahado-Singh,Ray O. Bahado-Singh,Katelyn Becker,Emily Schulz,Lindsay Meyerdirk,Jennifer A. Steiner,Jiyan Ma,Patrik Brundin +14 more
TL;DR: The need to investigate bile acids as potential biomarkers that predict PD and possibly reflect the progression of manifest PD is highlighted, with accurately measured concentrations of 18 bile acid in the serum of a prodromal mouse model of PD.
Journal ArticleDOI
Targeted Metabolic Profiling of Urine Highlights a Potential Biomarker Panel for the Diagnosis of Alzheimer's Disease and Mild Cognitive Impairment: A Pilot Study.
Ali Yilmaz,Ali Yilmaz,Zafer Ugur,Halil Bisgin,Sumeyya Akyol,Ray O. Bahado-Singh,Ray O. Bahado-Singh,George S. Wilson,George S. Wilson,Khaled Imam,Khaled Imam,Michael Maddens,Michael Maddens,Stewart F. Graham,Stewart F. Graham +14 more
TL;DR: This pilot study suggests that urine metabolomics may be useful for developing a test capable of diagnosing and distinguishing MCI and AD from cognitively healthy controls.
Journal ArticleDOI
Metabolomic Profiling of Cerebral Palsy Brain Tissue Reveals Novel Central Biomarkers and Biochemical Pathways Associated with the Disease: A Pilot Study
Zeynep Alpay Savasan,Ali Yilmaz,Zafer Ugur,Buket Aydas,Ray O. Bahado-Singh,Stewart F. Graham +5 more
TL;DR: The metabolomic profiling of post-mortem brain tissue from patients who died from cerebral palsy is reported for the first time, which could help to further investigate the complex etiopathophysiology of CP while identifying predictive, central biomarkers of CP.
Journal ArticleDOI
Lipid Profiling of Alzheimer's Disease Brain Highlights Enrichment in Glycerol(phospho)lipid, and Sphingolipid Metabolism.
Sumeyya Akyol,Zafer Ugur,Ali Yilmaz,Ilyas Ustun,Santosh Kapil Kumar Gorti,Kyungjoon Oh,Bernadette McGuinness,Peter Passmore,Patrick G. Kehoe,Michael Maddens,Brian D. Green,Stewart F. Graham +11 more
TL;DR: In this paper, a semi-targeted, fully quantitative lipidomics profiling method (Lipidyzer) was employed to compare the biochemical profiles of brain tissues from persons with mild and severe Alzheimer's disease (AD) and compared them with age-matched, cognitively normal controls.
Journal ArticleDOI
A Community-Based Study Identifying Metabolic Biomarkers of Mild Cognitive Impairment and Alzheimer's Disease Using Artificial Intelligence and Machine Learning.
Ali Yilmaz,Ali Yilmaz,Ilyas Ustun,Zafer Ugur,Sumeyya Akyol,William T. Hu,Massimo S. Fiandaca,Mark Mapstone,Howard J. Federoff,Michael Maddens,Stewart F. Graham,Stewart F. Graham +11 more
TL;DR: A comprehensive method of acquiring metabolomics data, coupled with machine learning techniques, has identified a strong panel of diagnostic biomarkers capable of identifying individuals with MCI and AD.