Z
Zhichao Zhou
Researcher at Karolinska University Hospital
Publications - 120
Citations - 3345
Zhichao Zhou is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: Purinergic receptor & Medicine. The author has an hindex of 23, co-authored 95 publications receiving 1810 citations. Previous affiliations of Zhichao Zhou include Wuhan University & Erasmus University Medical Center.
Papers
More filters
Journal ArticleDOI
VIBRANT: automated recovery, annotation and curation of microbial viruses, and evaluation of viral community function from genomic sequences.
TL;DR: VIBRANT is the first method to utilize a hybrid machine learning and protein similarity approach that is not reliant on sequence features for automated recovery and annotation of viruses, determination of genome quality and completeness, and characterization of viral community function from metagenomic assemblies.
Journal ArticleDOI
Bathyarchaeota: globally distributed metabolic generalists in anoxic environments.
TL;DR: This review summarizes the recent findings pertaining to the ecological, physiological and genomic aspects of Bathyarchaeota, highlighting the vital role of this phylum in global carbon cycling.
Journal ArticleDOI
Insights into the ecology, evolution, and metabolism of the widespread Woesearchaeotal lineages
Xiaobo Liu,Meng Li,Cindy J. Castelle,Alexander J. Probst,Alexander J. Probst,Zhichao Zhou,Jie Pan,Yang Liu,Jillian F. Banfield,Ji-Dong Gu,Ji-Dong Gu +10 more
TL;DR: Both lineage abundance distribution and co-occurrence network analyses across diverse biotopes confirmed metabolic complementation and revealed a potential syntrophic relationship between Woesearchaeota and methanogens, which is supported by metabolic modeling.
Journal ArticleDOI
Erythrocytes From Patients With Type 2 Diabetes Induce Endothelial Dysfunction Via Arginase I
Zhichao Zhou,Ali Mahdi,Yahor Tratsiakovich,Szabolcs Zahorán,Oskar Kövamees,Filip Nordin,Arturo Eduardo Uribe Gonzalez,Michael Alvarsson,Claes-Göran Östenson,Daniel C. Andersson,Ulf Hedin,Edit Hermesz,Jon O. Lundberg,Jiangning Yang,John Pernow +14 more
TL;DR: A novel mechanism behind endothelial dysfunction in T2DM that is induced by RBC arginase I and ROS is demonstrated and Targeting arginases I in RBCs may serve as a novel therapeutic tool for the treatment of endothelial Dysfunction in T1DM.
Journal ArticleDOI
Sunitinib-Induced Systemic Vasoconstriction in Swine Is Endothelin Mediated and Does Not Involve Nitric Oxide or Oxidative Stress
Mariëtte H.W. Kappers,Vincent J. de Beer,Zhichao Zhou,A.H. Jan Danser,Stefan Sleijfer,Dirk J. Duncker,Anton H. van den Meiracker,Daphne Merkus +7 more
TL;DR: It is indicated that sunitinib produces vasoconstriction selectively in the systemic vascular bed, without affecting pulmonary or coronary circulations and the mechanisms underlying the sunit inib-induced systemic hypertension are investigated.