Z
Zhijie Wan
Researcher at Zhengzhou University
Publications - 6
Citations - 79
Zhijie Wan is an academic researcher from Zhengzhou University. The author has contributed to research in topics: Arthritis & Micronutrient. The author has an hindex of 3, co-authored 5 publications receiving 28 citations.
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Journal ArticleDOI
Andrographolide ameliorates oxidative stress, inflammation and histological outcome in complete Freund's adjuvant-induced arthritis.
Shasha Luo,He Li,Jingjing Liu,Xiaoqian Xie,Zhijie Wan,Yale Wang,Zeyue Zhao,Xiaohan Wu,Xinxin Li,Min Yang,Xiaotian Li +10 more
TL;DR: Andrographolide acts as a protective agent for the treatment of complete freund's adjuvant induced rheumatoid arthritis by inhibiting lipid peroxidation and nitrite/nitrate levels in a dose-dependent manner, enhancing antioxidant enzyme activity, reducing levels of chemokines and inflammatory factors, preventing neutrophil accumulation and infiltration.
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Therapeutic effects of gentiopicroside on adjuvant-induced arthritis by inhibiting inflammation and oxidative stress in rats
Xiaoqian Xie,He Li,Yale Wang,Zhijie Wan,Shasha Luo,Zeyue Zhao,Jingjing Liu,Xiaohan Wu,Xinxin Li,Xiaotian Li +9 more
TL;DR: The therapeutic effects of GPS on AA rats are associated with anti-inflammation and antioxidation, and results indicate that GPS increases the levels of GSH-Px, SOD and GSH, and reduces the Levels of MDA and PCO.
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The combination of ursolic acid and empagliflozin relieves diabetic nephropathy by reducing inflammation, oxidative stress and renal fibrosis.
Xiaohan Wu,He Li,Zhijie Wan,Ran Wang,Jing Liu,Qingfeng Liu,Haiyun Zhao,Zhehuan Wang,Huiru Zhang,Hui Guo,Caihong Qi,Xiangyue Jiao,Xiaotian Li +12 more
TL;DR: In this paper, the effect of combining ursolic acid (UA) and empagliflozin (EM) in the treatment of diabetic nephropathy (DN) was explored.
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In vitro and in vivo assessment of the antibacterial activity of colistin alone and in combination with other antibiotics against Acinetobacter baumannii and Escherichia coli.
Yale Wang,He Li,Xiaoqian Xie,Xiaohan Wu,Xinxin Li,Zeyue Zhao,Shasha Luo,Zhijie Wan,Jingjing Liu,Lei Fu,Xiaotian Li +10 more
TL;DR: In-depth in vitro tests demonstrated that COL combined with DOR could be an attractive option, especially when COL MIC of the pathogen is ≥ 1 μg/ml, and in vivo tests suggested that intravenous CMS will be an effective and available therapeutic strategy for UTI due to MDR gram-negative pathogens.
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Hepatoprotective effect of gentiopicroside in combination with leflunomide and/or methotrexate in arthritic rats
Zhijie Wan,He Li,Xiaohan Wu,Haiyun Zhao,Ran Wang,Mengmeng Li,Jing Liu,Qingfeng Liu,Rui Wang,Xiaotian Li +9 more
TL;DR: Results show that GPS plays an antioxidant and anti-inflammatory role in LEF- and/or MTX-treated arthritic rats by affecting the Nrf2 and NF-κB signalling pathways, thus exerting hepatoprotective effects.