Z
Zhiqi Song
Researcher at Peking Union Medical College
Publications - 24
Citations - 3904
Zhiqi Song is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Viral load & Medicine. The author has an hindex of 14, co-authored 20 publications receiving 2840 citations.
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Journal ArticleDOI
From SARS to MERS, Thrusting Coronaviruses into the Spotlight
Zhiqi Song,Yanfeng Xu,Linlin Bao,Ling Zhang,Pin Yu,Yajin Qu,Hua Zhu,Wenjie Zhao,Yunlin Han,Chuan Qin +9 more
TL;DR: The research still needed to fully elucidate the pathogenic mechanism of these viruses, to construct reproducible animal models, and ultimately develop countermeasures to conquer not only SARS-CoV and MERS-coV, but also these emerging coronaviral diseases are outlined.
Journal ArticleDOI
The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice.
Linlin Bao,Wei Deng,Baoying Huang,Hong Gao,Jiangning Liu,Lili Ren,Qiang Wei,Pin Yu,Yanfeng Xu,Feifei Qi,Yajin Qu,Fengdi Li,Qi Lv,Wenling Wang,Jing Xue,Shuran Gong,Mingya Liu,Guanpeng Wang,Shunyi Wang,Zhiqi Song,Linna Zhao,Peipei Liu,Li Zhao,Fei Ye,Huijuan Wang,Weimin Zhou,Na Zhu,Wei Zhen,Haisheng Yu,Xiaojuan Zhang,Li Guo,Lan Chen,Conghui Wang,Ying Wang,Xinming Wang,Yan Xiao,Qiangming Sun,Hongqi Liu,Fanli Zhu,Chunxia Ma,Lingmei Yan,Mengli Yang,Jun Han,Wenbo Xu,Wenjie Tan,Xiaozhong Peng,Qi Jin,Guizhen Wu,Chuan Qin +48 more
TL;DR: This mouse model of SARS-CoV-2 infection will be valuable for evaluating antiviral therapeutic agents and vaccines, as well as understanding the pathogenesis of COVID-19.
Journal ArticleDOI
Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques.
Wei Deng,Linlin Bao,Jiangning Liu,Chong Xiao,Jiayi Liu,Jing Xue,Qi Lv,Feifei Qi,Hong Gao,Pin Yu,Yanfeng Xu,Yajin Qu,Fengdi Li,Zhiguang Xiang,Haisheng Yu,Shuran Gong,Mingya Liu,Guanpeng Wang,Shunyi Wang,Zhiqi Song,Ying Liu,Wenjie Zhao,Yunlin Han,Linna Zhao,Xing Liu,Qiang Wei,Chuan Qin +26 more
TL;DR: Results suggest that primary SARS-CoV-2 exposure protects against subsequent reinfection in rhesus macaques, and this has key implications for public health and economic initiatives if validated in human studies.
Posted ContentDOI
Reinfection could not occur in SARS-CoV-2 infected rhesus macaques
Linlin Bao,Wei Deng,Hong Gao,Chong Xiao,Jiayi Liu,Jing Xue,Qi Lv,Jiangning Liu,Pin Yu,Yanfeng Xu,Feifei Qi,Yajin Qu,Fengdi Li,Zhiguang Xiang,Haisheng Yu,Shuran Gong,Mingya Liu,Guanpeng Wang,Shunyi Wang,Zhiqi Song,Wenjie Zhao,Yunlin Han,Linna Zhao,Xing Liu,Qiang Wei,Chuan Qin +25 more
TL;DR: It is indicated that the primary SARS-CoV-2 infection could protect from subsequent exposures, which have the reference of prognosis of the disease and vital implications for vaccine design.
Posted ContentDOI
Lack of Reinfection in Rhesus Macaques Infected with SARS-CoV-2
Lin-lin Bao,Deng W,Han Gao,Cheng Xiao,Jing-Yi Liu,Jing Xue,Qi Lv,Pin Yu,Yanfeng Xu,Feifei Qi,Yajin Qu,Fengli Li,Zhiguang Xiang,Haisheng Yu,Shuran Gong,Mingya Liu,Guanpeng Wang,Shuiyun Wang,Zhiqi Song,Y.P. Liu,Wangli Zhao,Yunlin Han,Linna Zhao,Xuanyu Liu,Qunfang Wei,Cheng-Feng Qin +25 more
TL;DR: In this paper, neutralizing antibodies against SARS-CoV-2 might protect rhesus macaques which have undergone an initial infection from reinfection during early recovery days from initial infection characterized by weight loss, interstitial pneumonia and systemic viral dissemination mainly in respiratory and gastrointestinal tracts.