Q
Qi Lv
Researcher at Peking Union Medical College
Publications - 79
Citations - 6283
Qi Lv is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 29, co-authored 67 publications receiving 4420 citations.
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Journal ArticleDOI
Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients' B Cells.
Y Cao,Bin Su,Xianghua Guo,Wenjie Sun,Yong-Qiang Deng,Linlin Bao,Qinyu Zhu,Xu Zhang,Yinghui Zheng,Chenyang Geng,Xiaoran Chai,Runsheng He,Xiaofeng Li,Qi Lv,Hua Zhu,Wei Deng,Yanfeng Xu,Yanjun Wang,Luxin Qiao,Yafang Tan,Liyang Song,Guopeng Wang,Xiao-Xia Du,Ning Gao,Jiangning Liu,Junyu Xiao,Xiao-Dong Su,Zongmin Du,Yingmei Feng,Chuan Qin,Cheng-Feng Qin,Ronghua Jin,X. Sunney Xie +32 more
TL;DR: It is shown that human neutralizing antibodies could be efficiently discovered by high-throughput single B-cell sequencing in response to pandemic infectious diseases.
Journal ArticleDOI
The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice.
Linlin Bao,Wei Deng,Baoying Huang,Hong Gao,Jiangning Liu,Lili Ren,Qiang Wei,Pin Yu,Yanfeng Xu,Feifei Qi,Yajin Qu,Fengdi Li,Qi Lv,Wenling Wang,Jing Xue,Shuran Gong,Mingya Liu,Guanpeng Wang,Shunyi Wang,Zhiqi Song,Linna Zhao,Peipei Liu,Li Zhao,Fei Ye,Huijuan Wang,Weimin Zhou,Na Zhu,Wei Zhen,Haisheng Yu,Xiaojuan Zhang,Li Guo,Lan Chen,Conghui Wang,Ying Wang,Xinming Wang,Yan Xiao,Qiangming Sun,Hongqi Liu,Fanli Zhu,Chunxia Ma,Lingmei Yan,Mengli Yang,Jun Han,Wenbo Xu,Wenjie Tan,Xiaozhong Peng,Qi Jin,Guizhen Wu,Chuan Qin +48 more
TL;DR: This mouse model of SARS-CoV-2 infection will be valuable for evaluating antiviral therapeutic agents and vaccines, as well as understanding the pathogenesis of COVID-19.
Journal ArticleDOI
A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity.
Jingyun Yang,Wei Wang,Zimin Chen,Shuaiyao Lu,Fanli Yang,Zhenfei Bi,Linlin Bao,Fei Mo,Xue Li,Yong Huang,Weiqi Hong,Yun Yang,Yuan Zhao,Fei Ye,Sheng Lin,Wei Deng,Hua Chen,Hong Lei,Ziqi Zhang,Min Luo,Hong Gao,Yue Zheng,Yanqiu Gong,Xiaohua Jiang,Yanfeng Xu,Qi Lv,Dan Li,Manni Wang,Fengdi Li,Shunyi Wang,Guanpeng Wang,Pin Yu,Yajin Qu,Li Yang,Hongxin Deng,Aiping Tong,Jiong Li,Z. H. Wang,Jinliang Yang,Guobo Shen,Zhiwei Zhao,Yuhua Li,Jingwen Luo,Hongqi Liu,Wenhai Yu,Mengli Yang,Jingwen Xu,Junbin Wang,Haiyan Li,Haixuan Wang,Dexuan Kuang,Panpan Lin,Zhengtao Hu,Wei Guo,Wei Cheng,Yanlin He,Xiangrong Song,Chong Chen,Zhihong Xue,Shaohua Yao,Lu Chen,Xuelei Ma,Siyuan Chen,Maling Gou,Weijin Huang,Youchun Wang,Changfa Fan,Zhixin Tian,Ming Shi,Fu-Sheng Wang,Lunzhi Dai,Min Wu,Gen Li,Guangyu Wang,Yong Peng,Zhiyong Qian,Canhua Huang,Johnson Y.N. Lau,Zhenglin Yang,Yuquan Wei,Xiaobo Cen,Xiaozhong Peng,Chuan Qin,Kang Zhang,Guangwen Lu,Xiawei Wei +85 more
TL;DR: It is shown that a recombinant vaccine that comprises residues 319–545 of the RBD of the spike protein induces a potent functional antibody response in immunized mice, rabbits and non-human primates as early as 7 or 14 days after the injection of a single vaccine dose.
Journal ArticleDOI
Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques.
Wei Deng,Linlin Bao,Jiangning Liu,Chong Xiao,Jiayi Liu,Jing Xue,Qi Lv,Feifei Qi,Hong Gao,Pin Yu,Yanfeng Xu,Yajin Qu,Fengdi Li,Zhiguang Xiang,Haisheng Yu,Shuran Gong,Mingya Liu,Guanpeng Wang,Shunyi Wang,Zhiqi Song,Ying Liu,Wenjie Zhao,Yunlin Han,Linna Zhao,Xing Liu,Qiang Wei,Chuan Qin +26 more
TL;DR: Results suggest that primary SARS-CoV-2 exposure protects against subsequent reinfection in rhesus macaques, and this has key implications for public health and economic initiatives if validated in human studies.
Posted ContentDOI
Reinfection could not occur in SARS-CoV-2 infected rhesus macaques
Linlin Bao,Wei Deng,Hong Gao,Chong Xiao,Jiayi Liu,Jing Xue,Qi Lv,Jiangning Liu,Pin Yu,Yanfeng Xu,Feifei Qi,Yajin Qu,Fengdi Li,Zhiguang Xiang,Haisheng Yu,Shuran Gong,Mingya Liu,Guanpeng Wang,Shunyi Wang,Zhiqi Song,Wenjie Zhao,Yunlin Han,Linna Zhao,Xing Liu,Qiang Wei,Chuan Qin +25 more
TL;DR: It is indicated that the primary SARS-CoV-2 infection could protect from subsequent exposures, which have the reference of prognosis of the disease and vital implications for vaccine design.