Z
Zhuo Li
Researcher at California Institute of Technology
Publications - 26
Citations - 4649
Zhuo Li is an academic researcher from California Institute of Technology. The author has contributed to research in topics: Cytoskeleton & Cancer. The author has an hindex of 18, co-authored 24 publications receiving 3978 citations. Previous affiliations of Zhuo Li include Chinese Academy of Sciences & Beckman Research Institute.
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Journal ArticleDOI
Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis
Weiying Zhou,Weiying Zhou,Miranda Y. Fong,Yongfen Min,G. Somlo,Liang Liu,Liang Liu,Melanie R. Palomares,Yang Yu,Yang Yu,Amy Y. M. Chow,Sean Timothy Francis O’Connor,Andrew R. Chin,Yun Yen,Yafan Wang,Eric G. Marcusson,Peiguo Chu,Jun Wu,Xiwei Wu,Arthur X. Li,Zhuo Li,Hanlin Gao,Xiubao Ren,Mark Boldin,Pengnian Charles Lin,Shizhen Emily Wang +25 more
TL;DR: It is shown that miR-105, which is characteristically expressed and secreted by metastatic breast cancer cells, is a potent regulator of migration through targeting the tight junction protein ZO-1.
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Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis
Miranda Y. Fong,Weiying Zhou,Liang Liu,Aileen Y. Alontaga,Manasa Chandra,Jonathan Ashby,Amy Y. M. Chow,Sean Timothy Francis O’Connor,Shasha Li,Andrew R. Chin,George Somlo,Melanie R. Palomares,Zhuo Li,Jacob R. Tremblay,Akihiro Tsuyada,Guoqiang Sun,Michael A. Reid,Xiwei Wu,Piotr Swiderski,Xiubao Ren,Yanhong Shi,Mei Kong,Wenwan Zhong,Yuan Chen,Shizhen Emily Wang +24 more
TL;DR: It is demonstrated that, by modifying glucose utilization by recipient premetastatic niche cells, cancer-derived extracellular miR-122 is able to reprogram systemic energy metabolism to facilitate disease progression.
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Magnetosomes Are Cell Membrane Invaginations Organized by the Actin-Like Protein MamK
TL;DR: Using electron cryotomography, it seems that prokaryotes can use cytoskeletal filaments to position organelles within the cell.
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The structure of FtsZ filaments in vivo suggests a force-generating role in cell division.
TL;DR: In this paper, electron cryotomographic reconstructions of dividing Caulobacter crescentus cells where individual arc-like filaments were resolved just underneath the inner membrane at constriction sites were reported.
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Universal architecture of bacterial chemoreceptor arrays
Ariane Briegel,Davi R. Ortega,Elitza I. Tocheva,Kristin Wuichet,Zhuo Li,Songye Chen,Axel Müller,Cristina V. Iancu,Gavin E. Murphy,Megan J. Dobro,Igor B. Zhulin,Grant J. Jensen +11 more
TL;DR: This work shows that chemoreceptors of different classes and in many different species representing several major bacterial phyla are all arranged into a highly conserved, 12-nm hexagonal array consistent with the proposed “trimer of dimers” organization.