Institution
Al-Quds University
Education•East Jerusalem, Palestinian Territory•
About: Al-Quds University is a education organization based out in East Jerusalem, Palestinian Territory. It is known for research contribution in the topics: Population & Microemulsion. The organization has 956 authors who have published 1491 publications receiving 34293 citations.
Topics: Population, Microemulsion, Quantitative structure–activity relationship, Poison control, Medicine
Papers published on a yearly basis
Papers
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TL;DR: Svetlana A. Vizer,† Elena S. Sycheva,† Abed Al Aziz Al Quntar,‡ Nurzhan B. Kurmankulov,† Kazbek B. Yerzhanov,*, and Valery M. Dembitsky are the authors of this paper which aims to demonstrate the efforts towards in-situ applicability of EMT in the context of drug discovery.
Abstract: Svetlana A. Vizer,† Elena S. Sycheva,† Abed Al Aziz Al Quntar,‡ Nurzhan B. Kurmankulov,† Kazbek B. Yerzhanov,† and Valery M. Dembitsky* †A.B. Bekturov Institute of Chemical Sciences, 106 Sh. Walikhanov Street, Almaty 480100, Republic of Kazakhstan ‡Department of Material Engineering, Faculty of Engineering, Al Quds University, Abu Deis 51000, Palestine Institute of Drug Discovery, P.O. Box 45289, Jerusalem 91451, Israel
38 citations
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TL;DR: It was found that the most abundant monoterpenes, i.e. gamma-terpinene and p-cymene were decreased in the month of May since they are the biogenetic precursors of the phenolic terpene, thymol and carvacrol.
38 citations
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TL;DR: Traumatic events recollected by children living in areas of conflict, the prevalence of post-traumatic stress reactions and the relationship between children's and mothers' mental health were investigated.
Abstract: A cross-sectional study was conducted among 286 Palestinian children 9-18 years of age and their mothers in the Gaza Strip. Traumatic events recollected by children living in areas of conflict, the prevalence of post-traumatic stress reactions and the relationship between children's and mothers' mental health were investigated. The Gaza Traumatic Events Checklist, Impact of Event Scale (IES) and General Health Questionnaire (GHQ) were used to measure outcome. Children experienced on average four traumatic events; one-third reported significant post-traumatic stress reactions. IES scores were higher among girls and mothers' GHQ scores significantly predicted children's IES scores.
38 citations
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TL;DR: Platinum(IV) agents offer great potential in targeting, increasing efficacy, and decreasing toxicity of Platinum-based anticancer agents.
Abstract: Background: Intensive efforts have been implemented to improve the efficacy of platinum complexes especially with emerging cisplatin resistance and elevated cancer deaths. Platinum(IV) agents show better pharmacokinetics and decreased side effects compared to Platinum(II) agents. Methods: This review aims to summarize and categorize the strategies being employed to improve the efficacy of Platinum-based anticancer agents in recent years. Results: Nanoparticles and nanoplatforms offer a vast variety of strategies in targeting specific tumor types and delivering one or two lethal drugs simultaneously. Theranostic agents are being developed to achieve enhanced imaging and provide further insight into the activity of platinum containing chemotherapy. Moreover, photoactivation of Pt(IV) prodrugs specifically at the tumor site is gaining attention due to a controlled activity. A platinum agent formulated as large multi-activity complex is the most common strategy being employed. Conclusion: Platinum(IV) agents offer great potential in targeting, increasing efficacy, and decreasing toxicity of Platinum-based anticancer agents. The strategies being employed are aiming to increase specificity and targeting as well as provide more potent agents.
38 citations
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TL;DR: It is demonstrated that Cre‐mediated recombination using EIIA‐Cre, a Cre line expressed in germline, results in postnatal lethality by age of 3 weeks and decreased bone mineralization resembling total ablation of WWOX as in conventional null mice.
Abstract: WW domain-containing oxidoreductase (WWOX) is highly conserved in both human and murine. WWOX spans the second most common human chromosomal fragile site, FRA16D, and is commonly inactivated in multiple human cancers. Modeling WWOX inactivation in mice revealed a complex phenotype including postnatal lethality, defects in bone metabolism and steroidogenesis and tumor suppressor function resulting in osteosarcomas. For better understanding of WWOX roles in different tissues at distinct stages of development and in pathological conditions, Wwox conditional knockout mice were generated in which loxp sites flank exon 1 in the Wwox allele. We demonstrated that Cre-mediated recombination using EIIA-Cre, a Cre line expressed in germline, results in postnatal lethality by age of 3 weeks and decreased bone mineralization resembling total ablation of WWOX as in conventional null mice. This animal model will be useful to study distinct roles of WWOX in multiple tissues at different ages.
38 citations
Authors
Showing all 974 results
Name | H-index | Papers | Citations |
---|---|---|---|
Robert S. Stern | 120 | 761 | 62834 |
Renzo Guerrini | 93 | 688 | 32567 |
Abdul-Majid Wazwaz | 84 | 646 | 27216 |
Gad Baneth | 54 | 294 | 10692 |
Ahmed A. Moustafa | 48 | 380 | 9691 |
Gabriele Schönian | 46 | 126 | 7060 |
Valery M. Dembitsky | 44 | 283 | 7388 |
Morris Srebnik | 35 | 250 | 4994 |
Rafik Karaman | 34 | 168 | 3167 |
Ziad Abdeen | 34 | 143 | 14014 |
Ghaleb A. Husseini | 32 | 117 | 3851 |
Dieter Glebe | 31 | 119 | 3727 |
Alexander O. Terent'ev | 29 | 199 | 2794 |
Zaidoun Salah | 29 | 45 | 2188 |
Hisham M. Darwish | 25 | 42 | 2108 |