Astrakhan State University

About: Astrakhan State University is a education organization based out in Astrakhan, Russia. It is known for research contribution in the topics: Percolation & Carbamate. The organization has 547 authors who have published 565 publications receiving 2367 citations.

Mass transfer during drying of colloidal film beneath a patterned mask that contains a hexagonal array of holes

Abstract: We simulated an experiment in which a thin colloidal sessile droplet is allowed to dry out on a horizontal hydrophilic surface when a mask just above the droplet predominantly allows evaporation from the droplet free surface directly beneath the holes in the mask [Harris D J, Hu H, Conrad J C and Lewis J A 2007 Phys. Rev. Lett. 98 148301]. We considered one particular case when centre-to-centre spacing between the holes is much less than the drop diameter. In our model, advection, diffusion, and sedimentation were taken into account. FlexPDE was utilized to solve an advection-diffusion equation using the finite element method. The simulation demonstrated that the colloidal particles accumulate below the holes as the solvent evaporates. Diffusion can reduce this accumulation.

Intelligent Indoor Microclimate Control

Abstract: The article describes a model of the indoor climate control process, as well as structural diagrams of control modules based on neuro-fuzzy modeling. The developed model of intelligent climate control uses the value of the thermal comfort index PMV to control the values of temperature and humidity in the room. A mathematical model and algorithms for this model are presented. A two-layer neural network will allow you to predict the PMV index with sufficient accuracy, especially on data not from the training set. The fuzzy logic module uses a database of 33 rules for converting information from sensors (temperature and humidity) and a neural network into fuzzy information to regulate temperature and humidity values based on the value of the PMV comfort index. To take into account the dependence of the room temperature on the external temperature and the heater temperature, an additional Tdif module was introduced, which allowed to increase the efficiency of the model. Computational experiments have shown that based on this model, it is possible to obtain the economic efficiency of the indoor climate control system.

Optical Clearing of Human Skin Using Some Monosaccharides in vivo

Abstract: We present the results of in vivo optical immersion clearing of human skin by aqueous solutions of some immersion agents (ribose, glucose, and fructose monosaccharides and glycerol), obtained using optical coherence tomography (OCT). To assess the efficiency of optical clearing, we determined the values of the rate of change of the light scattering coefficient, obtained using the averaged A-scan of the OCT signal in the derma section at a depth of 350–700 μm. A good correlation was observed between the rate of change of the light scattering coefficient and the potential of the optical clearing. Using complex molecular simulation of the interaction of a number of immersion clearing agents with collagen mimetic peptide (GPH)3 using classical molecular dynamics and quantum chemistry, we found correlations between the efficiency of optical clearing and the energy of intermolecular interaction of cleaning agents with a fragment of collagen peptide.

Markers of Neuroinflammation and Apoptosis in the Temporal Lobe of Patients with Drug-Resistant Epilepsy

Abstract: Current antiepileptic strategies aim to normalize the interaction of the excitatory and inhibitory systems, which is ineffective in treating patients with drug-resistant epilepsy. Neuroinflammatory processes in the epileptic focus and its perifocal area can trigger apoptosis and also contribute to the development of drug resistance. The level of pro- and anti-apoptotic proteins (p-NF-kB, TNF-α, p53, FAS, caspase-3, caspase-9) was analyzed in intraoperative biopsies of the temporal lobe gray and white matter in the brain of patients with drug-resistant epilepsy. An increased level of pro-apoptotic proteins was revealed in the cortex and perifocal area’s white matter against the background of an imbalance of protective anti-apoptotic proteins. It appears that the activation of the extrinsic pathway of apoptosis occurs in the perifocal area, while in the epileptic focus, there are proteins responsible for the activation of the anti-apoptotic survival pathways. Active neuroinflammation in the epileptic focus and perifocal area of the temporal lobe may contribute to the development of the resistance to antiepileptic drugs and the progression of neurodegeneration in such patients.

Contact linearization of nondegenerate Monge-Ampère equations

Abstract: The present paper is devoted to the problem of transforming the classical Monge-Ampere equations to the linear equations by change of variables.