Institution
Fatima Jinnah Medical College
Education•Lahore, Pakistan•
About: Fatima Jinnah Medical College is a education organization based out in Lahore, Pakistan. It is known for research contribution in the topics: Population & Medicine. The organization has 243 authors who have published 289 publications receiving 2485 citations.
Topics: Population, Medicine, Health care, Mental health, Diabetes mellitus
Papers published on a yearly basis
Papers
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TL;DR: Using autozygosity mapping, a genetic locus (MCPH1) for primary microcephaly is identified, at chromosome 8p22-pter, in two consanguineous families of Pakistani origin, and the genetic heterogeneity of this condition is demonstrated.
Abstract: Primary (or "true") microcephaly is inherited as an autosomal recessive trait and is thought to be genetically heterogeneous. Using autozygosity mapping, we have identified a genetic locus (MCPH1) for primary microcephaly, at chromosome 8p22-pter, in two consanguineous families of Pakistani origin. Our results indicate that the gene lies within a 13-cM region between the markers D8S1824 and D8S1825 (maximum multipoint LOD score of 8.1 at D8S277). In addition, we have demonstrated the genetic heterogeneity of this condition by analyzing a total of nine consanguineous families with primary microcephaly.
158 citations
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TL;DR: The role of media and public health communications must be understood and explored further as they will be an essential tool for combating COVID-19 and future outbreaks.
Abstract: In Dec 2019, a novel pathogen emerged, and within weeks, led to the emergence of the biggest global health crises seen to date. The virus called 'SARS-CoV-2', causes coronavirus disease which was named 'COVID-19' by the World Health Organization (WHO). The speedy spread of this infection globally became a source of public worry and several unknowns regarding this new pathogen created a state of panic. Mass media became the major source of information about the novel coronavirus. Much like the previous pandemics of SARS (2003), H1N1 (2009), and MERS (2012), the media significantly contributed to the COVID-19 infodemics. In this review, we analyze the role of mass media and public health communications from December 31, 2019 to July 15, 2020, and make scientific inferences. The COVID-19 pandemic highlights multiple social, cultural, and economic issues arising from the media's arguable role. The racial prejudices linked to the origin of the virus prevented collaborations among scientists to find a solution. Media coverage of coronavirus news during geographical lockdowns, extended quarantines, and financial and social hardships induced fear and caused psychological stress. Domestic and elderly abuse upsurged. The unscientific cures and unverified medicines endorsed by the politicians and fake doctors proved harmful. The media played a worldwide role in coronavirus disease tracking and updates through live updates dashboard. The media allowed for timely interventions by the Center For Disease Control And Prevention (CDC) and the World Health Organization (WHO), enabling a rapid and widespread reach of public health communications. We saw an upward trend for the promotion of health and hygiene practices worldwide by adaption of safe health practices such as increased hand washing, use of face coverings, and social distancing. Media reinforced illness-preventing guidelines daily, and people were encouraged to use telehealth to meet their healthcare needs. Mass media has an imperative role in today's world and it can provide a unified platform for all public health communications, comprehensive healthcare education guidelines, and robust social distancing strategies while still maintaining social connections. It can enable equal access to healthcare, end discrimination, and social stigmatization. The role of media and public health communications must be understood and explored further as they will be an essential tool for combating COVID-19 and future outbreaks.
147 citations
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American University of Beirut1, University of Paris2, Kwame Nkrumah University of Science and Technology3, National Patient Safety Foundation4, Fatima Jinnah Medical College5, Peking Union Medical College6, Heidelberg University7, University of Michigan8, New York University9, Kenyatta National Hospital10, University of Barcelona11, University of California, San Francisco12, Hospital Italiano de Buenos Aires13, Huazhong University of Science and Technology14, World Health Organization15
TL;DR: The rapid guide includes three diagnosis recommendations and four management recommendations that cover patients with suspected or confirmed COVID-19 with different levels of disease severity, throughout the care pathway from outpatient facility or hospital entry, to home discharge.
Abstract: The World Health Organization (WHO) undertook the development of a rapid guide on the use of chest imaging in the diagnosis and management of COVID-19. The rapid guide was developed over two months using standard WHO processes, except for the use of 'rapid reviews' and online meetings of the panel. The evidence review was supplemented by a survey of stakeholders regarding their views on the acceptability, feasibility, impact on equity and resource use of the relevant chest imaging modalities (chest radiography, chest CT and lung ultrasound). The guideline development group had broad expertise and country representation. The rapid guide includes three diagnosis recommendations and four management recommendations. The recommendations cover patients with suspected or confirmed COVID-19 with different levels of disease severity, throughout the care pathway from outpatient facility or hospital entry, to home discharge. All recommendations are conditional and are based on low certainty evidence (n=2), very low certainty evidence (n=2), or expert opinion (n=3). The remarks accompanying the recommendations suggest which patients are likely to benefit from chest imaging and what factors should be considered when choosing the specific imaging modality. The guidance also offers considerations about implementation, monitoring and evaluation, and identifies research needs.
127 citations
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TL;DR: To investigate whether intrauterine growth retardation and preterm delivery in a poor population of South Asia was associated with altered maternal and fetal levels of folate, vitamin B12, and homocysteine, a large number of patients were enrolled.
Abstract: Objective. To investigate whether intrauterine growth retardation (IUGR) and preterm delivery in a poor population of South Asia was associated with altered maternal and fetal levels of folate, vitamin B12, and homocysteine.Subjects and methods. Hundred and twenty-eight pregnant women from a low socioeconomic strata in the city of Lahore, Pakistan were followed with ultrasound of fetal growth from the 12th week of pregnancy. Blood samples were drawn from the woman and the cord at delivery. Serum was analyzed by a chemiluminescent immunoassay for folate and vitamin B12 and by fluorescence polarization immunoassay for total homocysteine (tHcy).Results. Fourty-six infants showed IUGR. In term, but not preterm, deliveries with IUGR, maternal and cord blood folate levels were half of those in deliveries of normal birth weight infants (P ¼0.004 and P ¼0.005). The risk of IUGR was reduced among women with folate levels in the highest quartile (OR 0.31, 95% CI 0.10–0.84). There was no association between vitamin ...
119 citations
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TL;DR: The genetic heterogeneity of this condition is demonstrated with the identification of a second primary microcephaly locus (MCPH2) on chromosome 19q13.1–13.2 in two multi-affected consanguineous families.
Abstract: Primary microcephaly is a clinical diagnosis made when an individual has a head circumference of greater than 3 standard deviations below the age and sex matched population mean, mental retardation but without other associated malformations and no apparent aetiology. The majority of cases of primary microcephaly exhibit an autosomal recessive mode of inheritance. We now demonstrate the genetic heterogeneity of this condition with the identification of a second primary microcephaly locus (MCPH2) on chromosome 19q13.1-13.2 in two multi-affected consanguineous families. The minimum critical region containing the MCPH2 locus is defined by the polymorphic markers D19S416 and D19S420 spanning a region of approximately 7.6 cM.
103 citations
Authors
Showing all 244 results
Name | H-index | Papers | Citations |
---|---|---|---|
Abdul Waheed | 49 | 205 | 6057 |
Mohd Talib Latif | 36 | 295 | 5271 |
Farooq Naeem | 28 | 153 | 2536 |
Yasmin Rashid | 20 | 31 | 2720 |
Anam Iqbal | 17 | 24 | 805 |
Mulazim Hussain Bukhari | 14 | 61 | 652 |
Hussain Jafri | 11 | 16 | 1245 |
Haroon Rashid Chaudhry | 7 | 15 | 188 |
Rukhshan Khurshid | 7 | 41 | 173 |
Nuzhat Parveen Khawaja | 6 | 8 | 179 |
Sajjad Ashraf | 6 | 9 | 273 |
Kishver Tusleem | 5 | 7 | 85 |
Arshad N | 5 | 9 | 88 |
Najmi Rs | 5 | 5 | 83 |
Zouina Sarfraz | 5 | 37 | 48 |