Institute of Medical Sciences, Banaras Hindu University

About: Institute of Medical Sciences, Banaras Hindu University is a education organization based out in Varanasi, India. It is known for research contribution in the topics: Population & Visceral leishmaniasis. The organization has 3622 authors who have published 4579 publications receiving 84718 citations.

Quaternary alkaloids of Argemone mexicana

Abstract: Four quaternary isoquinoline alkaloids, dehydrocorydalmine, jatrorrhizine, columbamine, and oxyberberine, have been isolated from the whole plant of Argemone mexicana Linn. (Papaveraceae) and their structures established by spectral evidence. This is the first report of these alkaloids (dehydrocorydalmine, jatrorrhizine, columbamine, and oxyberberine) from Argemone mexicana and the Argemone genus.

New observations on carrying angle

Abstract: Based on experiments on fresh cadaveric and accidentally amputated 8 upper limbs of children, study of ulnae for presence and absence of non articular strip on the trochlear notch, measurements of carrying angle, length of forearm bones, pronation-supination, height and weight in 2250 infants, children and adults of various age groups and clinical observations on 800 cases of injuries around elbow many new facts have been observed about the development of the carrying angle and its significance in the etiopathogenesis of various types of fractures seen around the elbow The carrying angle develops in response to pronation of the forearm and is dependent on length of the forearm bones Lesser the length of forearm bones greater is the carrying angle So the carrying angle is more in shorter persons as compared to taller persons It is abduction at the shoulder and not the carrying angle which keeps the swinging upper limbs away from the side of the pelvis during walking Carrying angle is not a secondary sex character The type of fracture a child sustains after fall on outstretched hand is also determined by the value of the carrying angle A new type of fracture hitherto undescribed in the literature, T-Y fracture of the distal humeral epiphysis is also reported

Advanced stage of breast cancer hoist alkaline phosphatase activity: risk factor for females in India.

Abstract: Breast cancer is the most common neoplasm affecting women in the western world with an average frequency of 1 in 11, developing the malignancy and it is second most common cancer in India. Variations in serum levels of biochemical parameters especially alkaline phosphatase (ALP) changes may be of great help in diagnosis of breast carcinoma. Serum ALP activity was assayed in 388 histopathologically proven breast cancer patients using spectrophotometric methods and monitored association with cancer stages. Breast cancer is a female-biased disease and our study was conducted in a group of female patients with mean age of 48.67 ± 8.32 years. A significant increase in levels of ALP (809.65 ± 145.97 IU/L) was observed in stage IV of the disease. The logistic regression study gave a significant result (P 500 IU/L) with metastatic presentation. The present study besides being cost effective suggested the usefulness of ALP in differentiating breast cancer stages and metastasis.