Institution
Korean Ocean Research and Development Institute
Facility•Busan, South Korea•
About: Korean Ocean Research and Development Institute is a facility organization based out in Busan, South Korea. It is known for research contribution in the topics: Sea surface temperature & Gene. The organization has 1770 authors who have published 3032 publications receiving 50142 citations.
Topics: Sea surface temperature, Gene, Sediment, Bay, Population
Papers published on a yearly basis
Papers
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TL;DR: It is suggested that both modified SmP and SmPNPs have the potential to modulate gut microbial community, enhance the expression of immune related genes, and improve gut morphology.
Abstract: This study evaluated the modulation of gut microbiota, immune responses, and gut morphometry in C57BL/6 mice, upon oral administration of S. maxima-derived modified pectin (SmP, 7.5 mg/mL) and pectin nanoparticles (SmPNPs; 7.5 mg/mL). Metagenomics analysis was conducted using fecal samples, and mice duodenum and jejunum were used for analyzing the immune response and gut morphometry, respectively. The results of metagenomics analysis revealed that the abundance of Bacteroidetes in the gut increased in response to both modified SmP and SmPNPs (75%) as compared with that in the control group (66%), while that of Firmicutes decreased in (20%) as compared with that in the control group (30%). The mRNA levels of mucin, antimicrobial peptide, and antiviral and gut permeability-related genes in the duodenum were significantly (p 2-fold) upon modified SmP and SmPNPs feeding. Protein level of intestinal alkaline phosphatase was increased (1.9-fold) in the duodenum of modified SmPNPs feeding, evidenced by significantly increased goblet cell density (0.5 ± 0.03 cells/1000 µm2) and villi height (352 ± 10 µm). Our results suggest that both modified SmP and SmPNPs have the potential to modulate gut microbial community, enhance the expression of immune related genes, and improve gut morphology.
24 citations
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TL;DR: The main purposes for establishing the Korea ocean research stations (KORS) are for advancing an overall understanding of atmospheric and oceanic phenomena in the Yellow and East China Seas.
Abstract: The main purposes for establishing the Korea ocean research stations (KORS) are for advancing an overall understanding of atmospheric and oceanic phenomena in the Yellow and East China Seas...
24 citations
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TL;DR: Results illustrated that BHMB suppresses pro-inflammatory mediator and cytokine expression in LPS-stimulated RAW 264.7 cells by inhibiting the phosphorylation of ERK and p38 and the activation of NF-κB.
24 citations
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TL;DR: The TON_0002 gene, which is in close proximity to the DNA polymerase locus in Thermococcus onnurineus NA1, has been shown to encode an inorganic pyrophosphatase belonging to the haloacid dehalogenase superfamily, in which unique residues in motif I and II have been replaced with Trp and Gly, respectively.
Abstract: The TON_0002 gene, which is in close proximity to the DNA polymerase locus in Thermococcus onnurineus NA1, has been shown to encode an inorganic pyrophosphatase. Its genomic position and function suggest a role for pyrophosphate hydrolysis during DNA polymerization. This is the first report of an inorganic pyrophosphatase belonging to the haloacid dehalogenase superfamily, in which unique residues in motif I and II have been replaced with Trp and Gly, respectively. The optimum pyrophosphatase activity of the recombinant enzyme occurred at pH 6, and it displayed an absolute dependence on divalent metal ions, among which Ni2+ was the most efficient. The site-specific mutation of the Gly residue in motif II to Ala or Ser residue exhibited only a slight change in the enzymatic activity and the Km value.
24 citations
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TL;DR: In this article, the source, composition and reactivity of sedimentary organic carbon (OC) in a river-dominated continental marginal sea, the eastern Yellow Sea, was investigated.
24 citations
Authors
Showing all 1787 results
Name | H-index | Papers | Citations |
---|---|---|---|
Ian H. Campbell | 75 | 204 | 18767 |
Ravi Shankar | 66 | 672 | 19326 |
Claude F. Boutron | 57 | 176 | 11220 |
Carlo Barbante | 56 | 347 | 13942 |
Won Joon Shim | 56 | 211 | 10099 |
Jong-Seong Kug | 49 | 248 | 11337 |
Dong-Gyu Jo | 47 | 167 | 7599 |
Jong Seok Lee | 46 | 399 | 11661 |
Jong Seong Khim | 43 | 235 | 6783 |
Sang Hee Hong | 41 | 98 | 5804 |
Paolo Cescon | 40 | 131 | 4161 |
Jung-Hyun Lee | 38 | 215 | 5045 |
Narayanan Kannan | 38 | 140 | 6116 |
Nan Li | 38 | 183 | 5184 |
Sungmin Hong | 35 | 99 | 4130 |