Politehnica University of Bucharest

About: Politehnica University of Bucharest is a education organization based out in Bucharest, Romania. It is known for research contribution in the topics: Computer science & Cloud computing. The organization has 13528 authors who have published 16466 publications receiving 170211 citations. The organization is also known as: Universitatea Politehnica din București & University Politehnica of Bucharest.

Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview

Abstract: During the past few years, silver nanoparticles (AgNPs) became one of the most investigated and explored nanotechnology-derived nanostructures, given the fact that nanosilver-based materials proved to have interesting, challenging, and promising characteristics suitable for various biomedical applications. Among modern biomedical potential of AgNPs, tremendous interest is oriented toward the therapeutically enhanced personalized healthcare practice. AgNPs proved to have genuine features and impressive potential for the development of novel antimicrobial agents, drug-delivery formulations, detection and diagnosis platforms, biomaterial and medical device coatings, tissue restoration and regeneration materials, complex healthcare condition strategies, and performance-enhanced therapeutic alternatives. Given the impressive biomedical-related potential applications of AgNPs, impressive efforts were undertaken on understanding the intricate mechanisms of their biological interactions and possible toxic effects. Within this review, we focused on the latest data regarding the biomedical use of AgNP-based nanostructures, including aspects related to their potential toxicity, unique physiochemical properties, and biofunctional behaviors, discussing herein the intrinsic anti-inflammatory, antibacterial, antiviral, and antifungal activities of silver-based nanostructures.

ClickOS and the art of network function virtualization

Abstract: Over the years middleboxes have become a fundamental part of today's networks. Despite their usefulness, they come with a number of problems, many of which arise from the fact that they are hardware-based: they are costly, difficult to manage, and their functionality is hard or impossible to change, to name a few.To address these issues, there is a recent trend towards network function virtualization (NFV), in essence proposing to turn these middleboxes into software-based, virtualized entities. Towards this goal we introduce ClickOS, a high-performance, virtualized software middlebox platform. ClickOS virtual machines are small (5MB), boot quickly (about 30 milliseconds), add little delay (45 microseconds) and over one hundred of them can be concurrently run while saturating a 10Gb pipe on a commodity server. We further implement a wide range of middleboxes including a firewall, a carrier-grade NAT and a load balancer and show that ClickOS can handle packets in the millions per second.

Improving datacenter performance and robustness with multipath TCP

Abstract: The latest large-scale data centers offer higher aggregate bandwidth and robustness by creating multiple paths in the core of the net- work. To utilize this bandwidth requires different flows take different paths, which poses a challenge. In short, a single-path transport seems ill-suited to such networks.We propose using Multipath TCP as a replacement for TCP in such data centers, as it can effectively and seamlessly use available bandwidth, giving improved throughput and better fairness on many topologies. We investigate what causes these benefits, teasing apart the contribution of each of the mechanisms used by MPTCP.Using MPTCP lets us rethink data center networks, with a different mindset as to the relationship between transport protocols, rout- ing and topology. MPTCP enables topologies that single path TCP cannot utilize. As a proof-of-concept, we present a dual-homed variant of the FatTree topology. With MPTCP, this outperforms FatTree for a wide range of workloads, but costs the same.In existing data centers, MPTCP is readily deployable leveraging widely deployed technologies such as ECMP. We have run MPTCP on Amazon EC2 and found that it outperforms TCP by a factor of three when there is path diversity. But the biggest benefits will come when data centers are designed for multipath transports.