Pravara Rural College of Pharmacy

About: Pravara Rural College of Pharmacy is a based out in . It is known for research contribution in the topics: Petroleum ether & Gallic acid. The organization has 112 authors who have published 71 publications receiving 700 citations.

Polymers for Mucoadhesive Drug Delivery System: A Current Status

Abstract: To overcome the relatively short gastrointestinal (GI) time and improve localization for oral controlled or sustained release drug delivery systems, bioadhesive polymers that adhere to the mucin/epithelial surface are effective and lead to significant improvement in oral drug delivery. Improvements are also expected for other mucus-covered sites of drug administration. Bioadhesive polymers find application in the eye, nose, and vaginal cavity as well as in the GI tract, including the buccal cavity and rectum. This article lays emphasis mainly on mucoadhesive polymers, their properties, and their applications in buccal, ocular, nasal, and vaginal drug delivery systems with its evaluation methods.

Analgesic and anti-inflammatory activity of β-sitosterol isolated from Nyctanthes arbortristis leaves

Abstract: Nyctanthes arbortristis Linn. (Oleaceae) is one of the well-known Indian medicinal plant. Various extracts of leaves of the plant were screened for analgesic activity by hot plate test and acetic acid-induced writhings and anti-inflammatory activity by carrageenan-induced hind paw edema method at the dose of 50 mg/kg, i.p. Petroleum ether extract was found to be most active and hence subjected to activity-guided fractionation. Results showed that β-sitosterol (5, 10 and 20 mg/kg, i.p.) was responsible for the significant and dose-dependent activity comparable with the standard extract. β-Sitosterol from N. arbortristis leaves might be responsible for analgesic and anti-inflammatory activity.

Comparative In vitro Anthelmintic Activity of Mentha piperita and Lantana camara from Western India

Abstract: Methanol extracts from the leaves, stems and roots of Mentha piperita and Lantana camara were investigated for their anthelmintic activity against Pheritima posthuma . Each extract was studied in the bioassay at 20 mg/ml, which involved determination of time of paralysis and time of death of the worms. Both the extracts of both plants exhibited considerable anthelmintic activities, and the order of sensitivity of the extracts to the worms was stems > roots > leaves for the M. piperita and stems > leaves >roots for the L. camara . The methanol extracts of stems of both M. piperita and L. camar a were found to be the most active. Albendazole (20 mg/ml) and distilled water were included in the assay as standard reference drug and control, respectively. Key words: Mentha piperita, Lantana camara, Pheritima posthuma, In vitro anthelmintic activity. Dhaka Univ. J. Pharm. Sci. Vol.5(1-2) 2006 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website