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Institution

Rappaport Faculty of Medicine

About: Rappaport Faculty of Medicine is a based out in . It is known for research contribution in the topics: Population & Heparanase. The organization has 3205 authors who have published 3915 publications receiving 114533 citations.
Topics: Population, Heparanase, Medicine, Cancer, Pregnancy


Papers
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Journal ArticleDOI
TL;DR: It is demonstrated that introduction of mammalian GTPase activating protein (mGAP) reduces the isolation of Ras false positives in SRS screens of mammalian cDNA libraries, thereby significantly enhancing the efficiency of the system.
Abstract: The Sos recruitment system (SRS) is a novel genetic method for detecting protein-protein interactions. The method is based on localizing Sos, a Ras guanyl nucleotide exchange factor (GEF), to the plasma membrane through interaction between two fusion proteins. Mammalian Ras can bypass the requirement for a functional Ras GEF and represents a predictable false positive in this system. This report demonstrates that introduction of mammalian GTPase activating protein (mGAP) reduces the isolation of Ras false positives in SRS screens of mammalian cDNA libraries, thereby significantly enhancing the efficiency of the system.

79 citations

Journal ArticleDOI
TL;DR: The role of epicardial fat (eFat)-derived extracellular vesicles (EVs) in the pathogenesis of atrial fibrillation (AF) has never been studied as discussed by the authors.
Abstract: Background: The role of epicardial fat (eFat)-derived extracellular vesicles (EVs) in the pathogenesis of atrial fibrillation (AF) has never been studied. We tested the hypothesis that eFat-EVs tra...

79 citations

Journal ArticleDOI
TL;DR: The CD associated autoantibodies enigma, being an epiphenomenon or pathogenic, remains unresolved and presents a challenging area for future research.

79 citations

Journal ArticleDOI
TL;DR: Randomized, controlled trials of different prophylactic regimens to prevent thrombosis and/or bleeding in acute leukemia are urgently needed, particularly in patients with acute promyelocytic leukemia.

78 citations

Journal ArticleDOI
TL;DR: Improved performance on selective neurocognitive tests with addition of the 5-HT2A antagonist mianserin to typical antipsychotics indicates a possible role of the5-HT system in cognitive-enhancing effects.

78 citations


Authors

Showing all 3205 results

NameH-indexPapersCitations
Barry M. Brenner12154065006
Robert R. Edelman11960549475
David M. Goldenberg108123848224
Moussa B.H. Youdim10757442538
Aaron Ciechanover10531558698
Israel Vlodavsky9849434150
Basil S. Lewis9665160124
Michael Aviram9447931141
Abraham Weizman81101131083
Thomas N. Robinson8130926121
Peretz Lavie8132021532
Jacob M. Rowe7532820043
Hossam Haick7227915646
Walid Saliba7035919254
Gad Rennert6735017349
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20221
2021438
2020400
2019239
2018234
2017243