Roosevelt University

About: Roosevelt University is a education organization based out in Chicago, Illinois, United States. It is known for research contribution in the topics: Electron paramagnetic resonance & Population. The organization has 751 authors who have published 1482 publications receiving 44299 citations.

Copper(II) Complexes with Schiff Bases Containing a Disiloxane Unit: Synthesis, Structure, Bonding Features and Catalytic Activity for Aerobic Oxidation of Benzyl Alcohol

Abstract: Mononuclear copper(II) salen-type Schiff base complexes, CuIIL1–5 [H2L1 to H2L5 = tetradentate N,N,O,O ligands derived from 2-hydroxybenzaldehyde, 2,4-dihydroxybenzaldehyde, 3,5-dibromo-2-hydroxybenzaldehyde, 2-hydroxy-5-nitrobenzaldehyde, 5-chloro-2-hydroxybenzaldehyde and 1,3-bis(3-aminopropyl)tetramethyldisiloxane, respectively] were prepared in situ in the presence of a copper(II) salt or by direct complexation between a copper(II) salt and a presynthesised Schiff base. The compounds {CuL1, CuL1·0.5Py, CuL2·0.375CH2Cl2, (CuL3)[Cu(4-Me-Py)4Cl]Cl·2H2O, CuL4, CuL4·CHCl3 and CuL5, as well as the isolated ligand H2L3} were characterised by elemental analysis, spectroscopic methods (IR, UV/Vis, 1H NMR, EPR) and X-ray crystallography. The formation of a 12-membered central chelate ring in these complexes is effected by the tetramethyldisiloxane unit, which separates the aliphatic chains, thus significantly reducing the mechanical strain in such a chelate ring. We dub this a “shoulder yoke effect” by analogy with the load-spreading ability of such an ancient device. The coordination geometry of copper(II) in CuIIL1–5 can be described as tetrahedrally distorted square-planar. Maximum tetrahedral distortion of the coordination geometry expressed by the parameter τ4 was observed for CuL1 (0.460), while distortion was minimal for the two crystallographically independent molecules of CuL2 (0.219 and 0.284). The Si–O–Si bond angle varies markedly between 169.75(2)° for CuL1 and 154.2(3)° for CuL4·CHCl3. Charge-density and DFT calculations on CuL1 indicate high ionic character of the Si–O bonds in the tetramethyldisiloxane fragment. The new copper(II) complexes bearing the disiloxane moiety have been shown to act as catalyst precursors for the aerobic oxidation of benzyl alcohol to benzaldehyde mediated by the TEMPO radical, reaching yields and TONs up to 99 % and 990, respectively, under mild and environmentally friendly conditions (50 °C; MeCN/H2O, 1:1).

Relaxation: mapping an uncharted world.

Abstract: Nine hundred and forty practitioners of massage, abbreviated progressive muscle relaxation (PMR), yoga stretching, breathing, imagery, meditation, and various combination treatments described their technique experiences on an 82-item wordlist. Factor analysis yielded 10 interpretable relaxation categories: Joyful Affects and Appraisals (Joyful), Distant, Calm, Aware, Prayerful, Accepted, Untroubled, Limp, Silent, and Mystery. The relaxation response and cognitive/somatic specificity models predict Calm and Limp, which account for only 5.5% of the variance of relaxation experience. Unlike much of previous relaxation research, we found important technique differences. PMR and massage are associated with Distant and Limp; yoga stretching, breathing, and meditation with Aware; meditation with Prayerful, and all techniques except PMR with Joyful. Results are consistent with cognitive-behavioral relaxation theory and have implications for relaxation theory, treatment, training, assessment, and research. We close with a revised model of relaxation that posits three global dimensions: tension-relief, passive disengagement, and passive engagement.

Insights into the Use of C-Reactive Protein as a Diagnostic Index of Disease Severity in COVID-19 Infections.

Abstract: Approximately 20% of patients infected with SARS-CoV-2 (COVID-19) develop potentially life-threatening pathologies involving hyperinflammation, cytokine storm, septic shock complications, coagulation dysfunction, and multiple organ failure Blood levels of the prototypic acute phase reactant, C-reactive protein (CRP), which is hepatically synthesized and released in response to interleukin-6 stimulation, is markedly elevated in patients with COVID-19 Markedly high CRP levels correlate with poor prognosis for survival Insights into CRP structure-function relationships have uncovered both pro- and anti-inflammatory isoforms that may be used to monitor the extent of tissue damage associated with COVID-19 pathologies and prognoses Herein, rationale is given for interpretation of CRP blood levels as a simple, rapid, and cost-effective way to assess disease severity and help guide therapeutic options in COVID-19 patients

Associative nitrogen fixation, C4 photosynthesis, and the evolution of spittlebugs (Hemiptera: Cercopidae) as major pests of neotropical sugarcane and forage grasses.

Abstract: Neotropical grass-feeding spittlebugs of several genera are important pests of pasture grasses from the southeastern USA to northern Argentina, and of sugarcane from southern Mexico to southern Brazil, causing estimated reductions of up to 70% in yield and estimated monetary losses of 840-2100 million US dollars annually. With few exceptions, the species badly damaged by these spittlebugs are introduced C4 grasses that exhibit associative nitrogen fixation. This study synthesizes evidence that the pest status of many tropical and subtropical grass-feeding spittlebugs is linked to associative N-fixation in their C4 hosts. Recognition that associative N-fixation is a major factor in spittlebug host preferences should deepen understanding of spittlebug agricultural ecology and facilitate efforts to combat spittlebug pests. In particular, spittlebugs should be susceptible to manipulation of xylem transport solutes. However, reduction of nitrate fertilizer rates, increase in ammonium fertilizer rates, or enhancement of associative N-fixation as a consequence of genetic engineering could make hosts more susceptible to spittlebug attack. Because of their predilection for C4 grasses, spittlebugs present a clear counterexample to the hypothesis that herbivores prefer C3 plants to C4 plants. Finally, it appears that declines in atmospheric carbon dioxide levels during recent geological history promoted the proliferation of C4 grasses. This, compounded by human agricultural activities, has driven an ecological and evolutionary radiation of grass-feeding spittlebugs that presents continuing opportunities for the evolution of spittlebug pests.

Reconstructing Motherhood: The La Leche League in Postwar America

Abstract: In the 1950s: Formula was providing scientifically perfect food for babies. Anesthesia was saving mothers from the horrors of childbirth. Bottles were making it easy for anyone to care for the baby. Schedules and discipline from the moment of birth were preventing babies from ruling their parents' lives.... In 1956, seven women joined together in a movement that was to change the face of motherhood in America. They have devoted their lives to bringing mother and baby together again. -Kaye Lowman, The LLLove Story, 1978