Institution
Royal Devon and Exeter Hospital
Healthcare•Exeter, United Kingdom•
About: Royal Devon and Exeter Hospital is a healthcare organization based out in Exeter, United Kingdom. It is known for research contribution in the topics: Population & Randomized controlled trial. The organization has 2282 authors who have published 2526 publications receiving 78866 citations. The organization is also known as: RD&E.
Papers published on a yearly basis
Papers
More filters
••
TL;DR: Confidence in healthcare professionals in diagnosing and managing COPD is not reflected in their diagnoses or investigation and management strategies and they seem to favour cardiac over respiratory diagnoses.
18 citations
•
TL;DR: Patients with bilateral varicose veins preferred a single bilateral operation, based on one general anaesthetic and one admission only, less time off work, and discomfort on one occasion only, which should be considered when planning services for the treatment of varicoses.
Abstract: This questionnaire-based study investigated the preferences of patients with varicose veins for injection treatment or surgery, based on a series of explicit facts about each method. In all, 72 questionnaires were returned (77% response rate). Factors influencing patients in favour of injections were no time off work (38%) and no general anaesthetic (31%). A bandage on the leg for 3-6 weeks influenced 44% against injections. A lower chance of recurrence at 5-10 years influenced 80% of patients towards surgery. Overall, 25% expressed an overall preference for injections, and 63% preferred surgery (12% no preference). Patients with bilateral varicose veins were asked about their preferences for two unilateral day case operations or one bilateral inpatient procedure. The majority preferred a single bilateral operation, based on one general anaesthetic (88%) and one admission only (77%), less time off work (58%), and discomfort on one occasion only (50%). These preferences, expressed by well-informed patients, should be considered when planning services for the treatment of varicose veins.
18 citations
••
TL;DR: In this article, the authors report on the outcome of the Exeter Contemporary flanged cemented all-polyethylene acetabular component with a mean follow-up of 12 years (10 to 13).
Abstract: AimsWe report on the outcome of the Exeter Contemporary flanged cemented all-polyethylene acetabular component with a mean follow-up of 12 years (10 to 13.9). This study reviewed 203 hips in 194 patients. 129 hips in 122 patients are still in situ; 66 hips in 64 patients were in patients who died before ten years, and eight hips (eight patients) were revised. Clinical outcome scores were available for 108 hips (104 patients) and radiographs for 103 hips (100 patients).Patients and MethodsA retrospective review was undertaken of a consecutive series of 203 routine primary cemented total hip arthroplasties (THA) in 194 patients.ResultsThere were no acetabular component revisions for aseptic loosening. Acetabular revision was undertaken in eight hips. In four hips revision was necessitated by periprosthetic femoral fractures, in two hips by recurrent dislocation, in one hip for infection and in one hip for unexplained ongoing pain. Oxford and Harris hip scores demonstrated significant clinical improvement (a...
18 citations
••
TL;DR: The authors' experience indicates that instrumental perforation in benign esophageal disease carries a considerable mortality rate in spite of prompt recognition and surgical treatment, and successful dilation with mercury-weighted bougies can be achieved in 86% of benign strictures with an incidence of perforations similar to that for flexible esophagoscopy alone.
18 citations
••
TL;DR: This protocol describes the design of a randomised controlled trial to evaluate the clinical- and cost-effectiveness of a complex intervention care pathway compared with usual care for patients with chronic pain after total knee replacement.
Abstract: Approximately 20% of patients experience chronic pain after total knee replacement. There is little evidence for effective interventions for the management of this pain, and current healthcare provision is patchy and inconsistent. Given the complexity of this condition, multimodal and individualised interventions matched to pain characteristics are needed. We have undertaken a comprehensive programme of work to develop a care pathway for patients with chronic pain after total knee replacement. This protocol describes the design of a randomised controlled trial to evaluate the clinical- and cost-effectiveness of a complex intervention care pathway compared with usual care. This is a pragmatic two-armed, open, multi-centred randomised controlled trial conducted within secondary care in the UK. Patients will be screened at 2 months after total knee replacement and 381 patients with chronic pain at 3 months postoperatively will be recruited. Recruitment processes will be optimised through qualitative research during a 6-month internal pilot phase. Patients are randomised using a 2:1 intervention:control allocation ratio. All participants receive usual care as provided by their hospital. The intervention comprises an assessment clinic appointment at 3 months postoperatively with an Extended Scope Practitioner and up to six telephone follow-up calls over 12 months. In the assessment clinic, a standardised protocol is followed to identify potential underlying causes for the chronic pain and enable appropriate onward referrals to existing services for targeted and individualised treatment. Outcomes are assessed by questionnaires at 6 and 12 months after randomisation. The co-primary outcomes are pain severity and pain interference assessed using the Brief Pain Inventory at 12 months after randomisation. Secondary outcomes relate to resource use, function, neuropathic pain, mental well-being, use of pain medications, satisfaction with pain relief, pain frequency, capability, health-related quality of life and bodily pain. After trial completion, up to 30 patients in the intervention group will be interviewed about their experiences of the care pathway. If shown to be clinically and cost-effective, this care pathway intervention could improve the management of chronic pain after total knee replacement. ISRCTN registry (
ISRCTN92545361
), prospectively registered on 30 August 2016.
18 citations
Authors
Showing all 2288 results
Name | H-index | Papers | Citations |
---|---|---|---|
Andrew T. Hattersley | 146 | 768 | 106949 |
Timothy M. Frayling | 133 | 500 | 100344 |
Gordon D.O. Lowe | 105 | 560 | 44327 |
Rod S Taylor | 104 | 524 | 39332 |
Sian Ellard | 97 | 636 | 36847 |
Zoltán Kutalik | 90 | 321 | 42901 |
Michael N. Weedon | 87 | 201 | 60701 |
Masud Husain | 81 | 398 | 25682 |
David Melzer | 80 | 328 | 33458 |
Jonathan Mill | 78 | 301 | 36343 |
A. John Camm | 76 | 368 | 49804 |
David Silver | 74 | 227 | 81103 |
Jason D. Warren | 73 | 384 | 20588 |
Nicholas J. Talbot | 71 | 240 | 29205 |
Andrew R. Wood | 70 | 214 | 36203 |