Institution
University of Iowa Hospitals and Clinics
Healthcare•Iowa City, Iowa, United States•
About: University of Iowa Hospitals and Clinics is a healthcare organization based out in Iowa City, Iowa, United States. It is known for research contribution in the topics: Population & Medicine. The organization has 7201 authors who have published 9476 publications receiving 276995 citations. The organization is also known as: University of Iowa Hospitals & Clinics.
Topics: Population, Medicine, Cancer, Health care, Magnetic resonance imaging
Papers published on a yearly basis
Papers
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TL;DR: The results suggest that ACAT activity in CaCo-2 cells is stimulated by cholesterol delivered to the cells by way of taurocholate micelles, and is regulated by the expansion of the cholesterol substrate pool that is being utilized by an unsaturated ACAT enzyme.
83 citations
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TL;DR: In this paper, the authors found that bacteria are able to persist on scleral buckles by elaborating a glycocalyx matrix or biofilm that offers protection against host defenses and antimicrobial treatment.
83 citations
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TL;DR: It is found that persistence of encopresis at 6-month and 12-month follow-up was not related to the social competence or behavioral scores but was significantly related toThe inability to defecate and to the inability to relax the external sphincter during defecation attempts.
Abstract: The social competence and behavioral profiles of 38 encopretic children were evaluated, and the social competence and behavioral ratings were correlated with physiologic abnormalities found during anorectal manometric and EMG evaluation and with treatment outcome. When defecation was studied, 66% of encopretic children were not able to defecate rectal balloons and 63% were not able to relax the external anal sphincter during defecation attempts. Total social competence and behavior problem scores were not different for boys able and unable to defecate balloons. Total social competence scores were significantly lower in girls unable to defecate balloons than in those able to (P less than .006), whereas behavior problem scores were similar in girls able to and unable to defecate. We found that persistence of encopresis at 6-month and 12-month follow-up was not related to the social competence (P greater than .2) or behavioral scores (P greater than .2) but was significantly related to the inability to defecate (P less than .01) and to the inability to relax the external sphincter during defecation attempts (P less than .03).
82 citations
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TL;DR: Clinical features of a visual variant Alzheimer's disease, a disorder that might be seen by the ophthalmologist with visual symptoms and signs are described, and neuropsychological testing and magnetic resonance imaging provide supporting evidence for the diagnosis.
82 citations
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TL;DR: Focused surveillance among a subset of patients who met diagnosis code screening criteria with or without the addition of antimicrobial exposure-based screening was more sensitive than routine surveillance for detecting SSIs after arthroplasty and could be an efficient and readily standardized adjunct to traditional methods.
Abstract: Background. Screening methods that use automated data may streamline surgical site infection (SSI) surveillance and improve the accuracy and comparability of data on SSIs. We evaluated the use of automated inpatient diagnosis codes and pharmacy data to identify SSIs after arthroplasty. Methods. This retrospective cohort study at 8 hospitals involved weighted, random samples of medical records from 2128 total hip arthroplasty (THA) procedures performed from 1 July 2002 through 30 June 2004, and 4194 total knee arthroplasty (TKA) procedures performed from 1 July 2003 through 30 June 2005. We compared routine surveillance with screening of inpatient pharmacy data and diagnoses codes followed by medical record review to confirm SSI status. Results. Records from 696 THA and 1009 TKA procedures were reviewed. The SSI rates were nearly double those determined by routine surveillance (1.32% [95% confidence interval, 0.83%-1.81%] vs. 0.75% for THA; 1.83% [95% confidence interval, 1.43%-2.23%] vs. 0.71% for TKA). An inpatient diagnosis code for infection within a year after the operation had substantially higher sensitivity (THA, 89%; TKA, 81%), compared with routine surveillance (THA, 56%; TKA, 39%). Adding antimicrobial exposure of ≥7 days after the procedure increased the sensitivity (THA, 93%; TKA, 86%). Record review confirmed SSIs after 51% of THAs and 55% of TKAs that met diagnosis code criteria and after 25% of THAs and 39% of TKAs that met antimicrobial exposure and/or diagnosis code criteria. Conclusions. Focused surveillance among a subset of patients who met diagnosis code screening criteria with or without the addition of antimicrobial exposure-based screening was more sensitive than routine surveillance for detecting SSIs after arthroplasty and could be an efficient and readily standardized adjunct to traditional methods.
82 citations
Authors
Showing all 7249 results
Name | H-index | Papers | Citations |
---|---|---|---|
Nancy C. Andreasen | 138 | 604 | 73175 |
David G. Harrison | 137 | 492 | 72190 |
Antonio R. Damasio | 120 | 303 | 84833 |
David A. Lewis | 120 | 562 | 54796 |
Robert B. Wallace | 120 | 677 | 73951 |
Peter T. Scardino | 118 | 595 | 49550 |
Richard J.H. Smith | 118 | 1308 | 61779 |
Arthur M. Krieg | 111 | 400 | 50409 |
Daniel Tranel | 111 | 433 | 56512 |
Didier Pittet | 111 | 663 | 54319 |
David A. Schwartz | 110 | 958 | 53533 |
Edwin M. Stone | 110 | 588 | 44437 |
Val C. Sheffield | 109 | 392 | 44078 |
Robert A. Berg | 107 | 592 | 48480 |
Virend K. Somers | 106 | 615 | 54203 |