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Showing papers in "Advances in Medical Sciences in 2014"


Journal ArticleDOI
TL;DR: Seroprevalence and the associated socioeconomic and sociodemographic characteristics influencing H. pylori infection in children and adults in Polish population were assessed to assess improvement of socioeconomic status, sanitary and hygienic conditions and the education of the society.

60 citations


Journal ArticleDOI
TL;DR: It is suggested that in women with GDM, glyburide is as effective as insulin, but the risks of neonatal hypoglycemia, high fetal birth weight, and macrosomia were higher.

58 citations


Journal ArticleDOI
TL;DR: The epigenetic mechanism identified that changes expression of certain genes involved in insulin/insulin-like growth factor signaling in VSELs keeps these cells quiescent in adult tissues and provides a novel view of the stem cell compartment, IIS, tissue/organ rejuvenation, aging, and cancerogenesis.

50 citations


Journal ArticleDOI
TL;DR: MIP-1β concentration in ascitic fluid may distinguish patients with and without SBP with satisfactory sensitivity and specificity and Chemokines should be further explored for diagnostic use.

49 citations


Journal ArticleDOI
TL;DR: The results suggest that poor metabolic control of diabetes together with smoking and inadequate oral hygiene increase the risk of severe periodontal destruction in patients with type 1 diabetes.

49 citations


Journal ArticleDOI
TL;DR: There is no standard effective treatment for pancreatic cancer anorexia-cachexia syndrome and further studies are needed to unravel the basic mechanisms underlying CACS and to develop newer therapeutic strategies with the hope to improve the quality of life of pancreaticcancer patients.

37 citations


Journal ArticleDOI
TL;DR: The availability of antineoplastic monoclonal antibodies, small molecules and newer cytotoxics as well as the anti-angiogenic bevacizumab and the ALK-inhibitor crizotinib has recently changes the treatment algorithm of advanced non-small cell lung cancer.

25 citations


Journal ArticleDOI
TL;DR: The prevalence of intracranial arterial stenosis in children with SCA classified as at low risk of stroke by TCD mean velocity <170 cm/s is high and children with stenosis are at higher risk of brain parenchymal injury as they have more silent cerebral infarcts.

25 citations


Journal ArticleDOI
TL;DR: IgG4 at cut-off 210 mg/dl showed the best sensitivity and specificity in AIP diagnosis compared to IgG and anti-CAIIAb, however elevations of serum IgG4 may be seen in subjects without AIP, including pancreatic cancer.

25 citations


Journal ArticleDOI
TL;DR: Quantitative analysis of the concentration of lipids and lipoproteins in blood serum in patients withPrimary hypertension and hyperhomocysteinemia may suggest that this type of human population might be more susceptible to atherosclerosis than those with primary hypertension and normal values of homocysteine.

23 citations


Journal ArticleDOI
TL;DR: Higher serum fetuin A concentration found in children with NAFLD compared to the control group support the hypothesis that atherosclerotic processes may develop faster in hepatopatic obese patients.

Journal ArticleDOI
TL;DR: Evaluation of different parts of the plant during the massive blooming phase revealed that the highest amount of flavonoids and radical scavenging activity are characteristic for blooms of the plants.

Journal ArticleDOI
TL;DR: It is demonstrated that the protein expression of p53, CDH1 and CDX2 significantly discriminates young patients with gastric cancer who have a better prognostic outlook from older patients, but this difference in expression does not contribute to a survival benefit.

Journal ArticleDOI
TL;DR: The cognitive brain oscillatory specificity diminished with increasing age, and neither functional brain specificity was observed for the amplitudes of the low-frequency (δ, θ, α) oscillations during the cognitive processing, which diminished with decreasing age.

Journal ArticleDOI
TL;DR: An early and significant increase of peripheral blood neutrophil CD54/ICAM-1 expression is found, specific for S-AP but not for M-AP, which may provide a good marker predicting severe course of pancreatitis.

Journal ArticleDOI
TL;DR: A reduction in QoL is confirmed in patients with multiple sclerosis in Poland compared with the general population, as well as the modifiable risk factors (e.g. type of treatment) that may affectQoL.

Journal ArticleDOI
TL;DR: Not only infants who fail the initial screening but also the ones with risk factors of hearing impairment should be referred to the centers that are capable of providing the necessary diagnostic services required for the second stage of the UNHSP, according to the authors.

Journal ArticleDOI
TL;DR: The values of placental vascular indices are constant between the 22nd and 41st week of a normal pregnancy and placental volume measured with the use of the VOCAL program increases between 22nd to 41stweek of anormal pregnancy.

Journal ArticleDOI
TL;DR: In children with congenital heart defects undergoing cardiosurgical treatment with the use of ECC the assessing CRP values in the first postoperative day remains questionable and single CRP assessment in early postoperative period in these groups of children can lead to over-diagnosis of infections and antibiotics abuse.


Journal ArticleDOI
TL;DR: Detergent-based methods are the most effective protocols for cell removal and ECM preservation of aortic valve conduits of AVCs and may be excellent scaffolds for recellularisation.

Journal ArticleDOI
TL;DR: The basic discoveries in cell biology have moved regenerative medicine into the center of biomedical research worldwide with a major translational impact on tissue engineering as well as transplantation medicine.

Journal ArticleDOI
TL;DR: Type 2 diabetes did not influence early and late mortality in patients with LMD treated with cardiac surgery, but the presence of diabetes was associated with more frequent hospitalizations.

Journal ArticleDOI
TL;DR: All EPI-pigs, independent of age at PDL-operation, displayed adaptive gut changes, however the EPI -pigs operated early after weaning appeared more sensitive, probably related to their gut maturity and possibly explaining the growth arrest seen in these pigs.

Journal ArticleDOI
TL;DR: OPG is associated with cardiovascular risk factors, CIMT, but not with the presence of asymptomatic carotid plaques in non diabetic postmenopausal women.

Journal ArticleDOI
TL;DR: This disease should be taken into consideration in differential diagnosis in patients with root syndromes accompanied by back pain and usually fever as well as increased values of CRP and ESR.

Journal ArticleDOI
TL;DR: The persistence of the antral expression of receptors after eradication, at a level comparable to the gastric cancer group, suggests their eventual role in the progression of changes initiated by H. pylori toward carcinogenesis.

Journal ArticleDOI
TL;DR: Artificial neural networks are a promising multidimensional tool facilitating clinical decision making in patients with CRS but their quality depended on mathematical representation of the surgery result.

Journal ArticleDOI
TL;DR: Higher frequency of both OX40 and 4-1BB positive cells in T1D children in comparison to controls was showed, and it seems that observed differences might be more pronounced in children<5 years of age than in older subjects.

Journal ArticleDOI
TL;DR: Investigation has demonstrated that the testicular failure following chronic ethanol consumption and diabetes type I in male rats accompanied CYP2E1 mRNA over-expression in testes, allowing supposing the involvement of CYP 2E1 into the non-specific pathogenetic mechanisms of male infertility under above-mentioned pathologies.