Showing papers in "American Journal of Ophthalmology in 2012"

TL;DR: Tube shunt surgery had a higher success rate compared to trabeculectomy with MMC during 5 years of follow-up in the TVT Study and both procedures were associated with similar IOP reduction and use of supplemental medical therapy at 5 years.

TL;DR: The rates of late postoperative complications, reoperation for complications, and cataract extraction were similar with both surgical procedures after 5 years of follow-up, and a large number of surgical complications were observed.

TL;DR: DMEK provided faster and more complete visual rehabilitation when compared with DSAEK, however, there were no significant differences concerning endothelial cell survival within a 6-month follow-up.

TL;DR: It is indicated that bevacizumab can escape from the eye into the systemic circulation and reduce the serum level of VEGF in infants with ROP.

TL;DR: From 2000 to 2010 the incidence of legal blindness from AMD fell to half the baseline incidence, and the bulk of the reduction occurred after the introduction of intravitreally injected inhibitors of vascular endothelial growth factor in 2006.

TL;DR: Cosmetic filler injections into the glabellar region or nasolabial fold can cause retinal artery occlusion and is associated with painful blindness, a thin choroid, brain infarction, and poor visual outcomes, particularly when autologous fat is used.

TL;DR: These data are necessary to understand the marked changes in human retina from late gestation to early adulthood and provide qualitative and quantitative morphologic information required to interpret the changes in hyper- and hyporeflexive bands in pediatric spectral-domain optical coherence tomography images at the same ages.

TL;DR: The presence of hyperreflective foci in the outer retina is closely associated with a disrupted ELM and IS/OS line on SD-OCT images and decreased VA in DME and the logarithm of minimal angle of resolution visual acuity is decreased.

TL;DR: In this paper, the authors used spectral-domain optical coherence tomography (SDOCT) images to correlate human foveal development visualized by SDOCT with histologic specimens.

TL;DR: OSD is more common in patients with increasing glaucoma severity and is associated with poorer glauca-related QoL and higher exposure to BAK and more exposure to topical beta blockers and topical carbonic anhydrase inhibitors.

TL;DR: In human nonvitrectomized eyes, the aqueous half-life of 0.5 mg intravitreally injected ranibizumab is 7.19 days, slightly shorter than the half- life of 9.82 days previously determined for bevacizumAB by comparable methods.

TL;DR: Observed vision health disparities suggest a need for educational and innovative interventions among socioeconomically disadvantaged groups.

TL;DR: The status of the COST line, in conjunction with the IS/OS junction, is a useful prognostic factor after ERM surgery, and is significantly correlated with BCVA postoperatively.

TL;DR: CXL improved UCVA and BSCVA in the study patients, most likely by significantly reducingCorneal asymmetry and corneal as well as total wavefront aberrations.

TL;DR: Nonmydriatic ultrawide field images compare favorably with dilated ETDRS photography and dilated fundus examination in determining DR and DME severity; however, they are acquired more rapidly.

TL;DR: Yeasts were the most common cause of culture-proven unilateral or bilateral endogenous fungal endophthalmitis and generally is associated with poor visual acuity outcomes, especially when caused by molds.

TL;DR: At diagnosis, keratoconus is often more advanced in children than in adults, with faster disease progression, and early detection and close monitoring are therefore crucial in young patients.

TL;DR: CXL in thin corneas with minimum corneal thickness less than 400 μm after epithelial removal seems to result in a significant endothelial cell density decrease postoperatively, which is not related to other intraoperative or postoperative complications.

TL;DR: DMEK combined with cataract surgery (triple procedure) can routinely be performed in cases of endothelial dystrophy andCataract and had no adverse effect on endothelial function or graft adhesion and did not increase the likelihood of postoperative complications.

TL;DR: Severe ocularsurface symptoms reduce the quality of life of Miami VAMC veterans and eye care professionals should be vigilant in eliciting ocular surface complaints from their patients.

TL;DR: Fovea-sparing ILM peeling results in better visual and anatomic outcomes for the treatment of foveal RD attributable to myopic traction maculopathy.

TL;DR: Dry eye syndrome is a disease associated with depression and post-traumatic stress disorder, and is prevalent among male and female veterans receiving eye care services, and could be driven by underlying disease physiology or medications used to treat psychiatric conditions.

TL;DR: The most likely cause of this outbreak of endophthalmitis after intravitreal bevacizumab injection was contamination during syringe preparation by the compounding pharmacy.

TL;DR: Photoreceptor disruption detected by OCT and P1 implicit time delay on mfERG were significant predictors of poor visual recovery after ERM surgery and final BCVA was significantly correlated with preoperative photoreceptor integrity and P 1 implicit time.

TL;DR: Patients experiencing a longer delay between their first symptoms of CNV and their first anti-VEGF treatment have a significantly lower chance of improving vision at 6 months following anti-Vascular endothelial growth factor therapy.

TL;DR: Patients with AIDS, especially those with severely compromised immune systems, remain at risk for developing CMV retinitis in the HAART era, although the incidence rate is reduced from that observed in the pre-HAART era.

TL;DR: Despite the high prevalence of POAG in African Americans and Hispanics, the largest group in the United States is currently among older non-Hispanic white women but is expected to shift to Hispanic men over the next few decades.

TL;DR: In this article, the relationship between the choroidal thickness and the total and sub-foveal blood flow in healthy young Japanese subjects was investigated by using enhanced depth imaging optical coherence tomography (EDI-OCT).

TL;DR: RPE-choroid graft transplantation may maintain macular function for up to 7 years after surgery, with relatively low complication and recurrence rates and this surgery may be an alternative for patients with AMD who cannot undergo other standard treatment.

TL;DR: A review of the medical literature and pertinent Internet postings combined with analysis of key studies with expert opinion regarding the use of aflibercept for the treatment of exudative age-related macular degeneration is presented in this paper.