Treatment outcomes in the tube versus trabeculectomy (TVT) study after five years of follow-up
Steven J. Gedde,Joyce C. Schiffman,William J. Feuer,Leon W. Herndon,James D. Brandt,Donald L. Budenz +5 more
TLDR
Tube shunt surgery had a higher success rate compared to trabeculectomy with MMC during 5 years of follow-up in the TVT Study and both procedures were associated with similar IOP reduction and use of supplemental medical therapy at 5 years.About:
This article is published in American Journal of Ophthalmology.The article was published on 2012-05-01 and is currently open access. It has received 829 citations till now. The article focuses on the topics: Trabeculectomy & Trabectome.read more
Citations
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The Pathophysiology and Treatment of Glaucoma: A Review
TL;DR: Primary care physicians can play an important role in the diagnosis of glaucoma by referring patients with positive family history or with suspicious optic nerve head findings for complete ophthalmologic examination and can improve treatment outcomes by reinforcing the importance of medication adherence and persistence.
Journal ArticleDOI
Primary open-angle glaucoma.
Robert N. Weinreb,Christopher Kai-Shun Leung,Jonathan G Crowston,Felipe A. Medeiros,David S. Friedman,Janey L. Wiggs,Keith R Martin +6 more
TL;DR: Primary open-angle glaucoma (POAG) is the most common type and management of POAG includes topical drug therapies and surgery to reduce IOP, although new therapies targeting neuroprotection of RGCs and axonal regeneration are under development.
Journal ArticleDOI
Postoperative complications in the Tube Versus Trabeculectomy (TVT) study during five years of follow-up.
Steven J. Gedde,Leon W. Herndon,James D. Brandt,Donald L. Budenz,William J. Feuer,Joyce C. Schiffman +5 more
TL;DR: The rates of late postoperative complications, reoperation for complications, and cataract extraction were similar with both surgical procedures after 5 years of follow-up, and a large number of surgical complications were observed.
Journal ArticleDOI
The Ahmed versus Baerveldt study: three-year treatment outcomes.
Panos G. Christakis,Jeffrey W. Kalenak,James C. Tsai,David Zurakowski,Jeffrey A. Kammer,Paul Harasymowycz,Juan J. Mura,Louis B. Cantor,Iqbal Ike K. Ahmed +8 more
TL;DR: Both implants were effective in reducing IOP and the need for glaucoma medications and the Baerveldt group had a lower failure rate and a lower IOP on fewer medications than the Ahmed group, but had a small risk of hypotony that was not seen in the Ahmed Group.
Journal ArticleDOI
Minimally-invasive glaucoma surgeries (MIGS) for open angle glaucoma: A systematic review and meta-analysis.
TL;DR: Although MIGS seem efficient in the reduction of the IOP and glaucoma medication and show good safety profile, this evidence is mainly derived from non-comparative studies and further, good quality RCTs are warranted.
References
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TL;DR: The first adequately powered randomized trial with an untreated control arm to evaluate the effects of IOP reduction in patients with open-angle glaucoma who have elevated and normal IOP showed considerable beneficial effects of treatment that significantly delayed progression.
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The advanced glaucoma intervention study (AGIS): 7. the relationship between control of intraocular pressure and visual field deterioration
Fred Ederer,Ma,Douglas E. Gaasterland,E. Kenneth Sullivan,Allen D. Beck,Bruce E. Prum,Marshall N. Cyrlin,Howard S. Weiss +7 more
TL;DR: In both analyses low intraocular pressure is associated with reduced progression of visual field defect, supporting evidence from earlier studies of a protective role for low intracular pressure in visual field deterioration.
Journal ArticleDOI
Comparison of glaucomatous progression between untreated patients with normal-tension glaucoma and patients with therapeutically reduced intraocular pressures
TL;DR: Intraocular pressure is part of the pathogenic process in normal-tension glaucoma and therapy that is effective in lowering intraocular pressure and free of adverse effects would be expected to be beneficial in patients who are at risk of disease progression.
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