Showing papers in "Annals of Diagnostic Pathology in 2013"

TL;DR: Decalcification of bone biopsies with EDTA or formic acid agents was associated with a significant improvement in recovered nucleic acid quantity and quality.

TL;DR: It was evident that combination of napsin-A, TTF-1, CK5/6, and p63 was the best immunohistochemical panel in differentiating ADC from SCC of the lung in this study.

TL;DR: This study forms the largest documented series on cervical neuroendocrine carcinomas from the authors' country, testifying the current histopathologic classification system.

TL;DR: Sirtuin-3 (SIRT3) was immunostained in 94 samples of esophageal cancer tissues and semiquantified using the HSCORE method to evaluate the predictive value of SIRT3 expression levels on esophagal cancer outcome.

TL;DR: This work reports a case of dedifferentiated solitary fibrous tumor, with heterologous osteosarcomatous and rhabdomyosarComatous elements, arising in the deep soft tissue of the thigh of a 59-year-old man, juxtaposed to pleomorphic, high-grade malignant neoplasm of 2 distinct lineages.

TL;DR: The depth of invasion of the tubal wall and the presence of carcinoma in the fimbriated end even without invasion are important prognostic indicators.

TL;DR: The morphological spectrum of pseudoangiomatous features and aberrant expression of CD31 and FLI1 in atypical fibroxanthoma and pleomorphic dermal sarcoma may lead to an erroneous diagnosis of cutaneous angiosarcoma.

TL;DR: Investigation of the relations between Med19 and BMPs in BCa found that Med19 is a critical factor involved in the invasiveness and promotion of bone metastasis of BCa, possibly via BMP-2.

TL;DR: Panel of carbonic anhydrase IX, galectin-3, CK7, and α-methylacyl coenzyme a racemase is sensitive and specific for the differential diagnosis of the renal epithelial tumors.

TL;DR: Clinical implications of the clinicopathologic features of candidal infection in biopsies of a large retrospective cohort of patients with premalignant oral leukoplakia from eastern China were assessed and a subpopulation was identified that was more liable to candidal infections was identified.

TL;DR: Nuclear factor κB may participate in the malignant phenotype acquisition process of the oral squamous cell carcinoma in its late stages, whereas COX-2 may be involved in the early stages of oral carcinogenesis process.

TL;DR: It is suggested that Axl and prostasin expression may be closely related to carcinogenesis, metastasis, and prognosis of ovarian adenocarcinoma.

TL;DR: It is suggested that FP and FP-like lesions are commonly encountered in defunctioned resection specimens.

TL;DR: The degree of macroscopic lesion of atherosclerosis increased proportionally with the increase in the density of mast cell chymase and tryptase and in the intensity of lipid deposition and with the percentage of collagen in the atherosclerotic plaques.

TL;DR: Analysis of expression of minichromosome maintenance 2, Ki-67, and geminin in oral nevi and melanomas indicates that these markers may be involved in the pathogenesis of oral melanomas and could be eventually useful as an additional diagnostic tool for differential diagnosis of oral benign and malignant melanocytic lesions.

TL;DR: 2 cases of endobronchial pulmonary carcinoid tumor with superimposed Aspergillus colonization are described, both of which have the possibility of "scar carcinoma."

TL;DR: Calretinin can be a good tool in ruling out the diagnosis of Hirschsprung disease, by showing positive staining in ganglion cells and intrinsic nerve fibers, whereas AChE is useful in confirming the diagnosis, by revealing activity of this enzyme in hypertrophied nerve fibers.

TL;DR: Strong up-regulation and the role of HIF-1α suggest that Hif-1 α could be an important factor in the onset and progression of cervical cancer and could be a attractive therapeutic molecular target for that type of cancer.

TL;DR: The results suggest that the expression of proinflammatory cytokines (IL-17 and TNF-α) contributes to the mechanisms of kidney transplant rejection.

TL;DR: From the present study, up-regulation of HSP 70, in the form of its intense and diffuse expression, may be blamed in pathogenesis of vitiligo.

TL;DR: The palate was the most frequent location for salivary gland tumors and tumors have a propensity to occur at the palate than any other sites, therefore, any lesion arising from the palate should be considered as a possible salivARY gland tumor.

TL;DR: A total of 8 cases of secretory carcinoma of breast (SCB) were found in the Section of Histopathology, Department of Pathology & Microbiology, Aga Khan University Hospital Karachi from May 2004 to December 2011 as discussed by the authors.

TL;DR: It is suggested that CD133 may serve as a novel candidate biomarker for risk assessment of malignant potential of OLP and be significantly associated with malignant progression in a longitudinal series of patients with OLP.

TL;DR: This work describes the first case of IgG4-associated IPT, lymphoplasmacytic type in the urinary bladder, arising in the bladder with the secondary involvement of the sigmoid colon.

TL;DR: 5 paratesticular tumors, which manifested ovarian-type stroma and various serous müllerian epithelial structures including serous fallopian-like epithelium and proliferations closely mimicking cystic serous borderline tumors of the ovary, are presented.

TL;DR: The origin of ossifying fibroma and juvenile OF seems to be distinct from each other with OF arising from periodontal ligament and JOF arising from precursor myxoid tissue of paranasal sinuses.

TL;DR: Cognizance of this rare tumor in the pediatric population coupled with antiretroviral therapy and prompt initiation of multimodality treatment may, in the future, facilitate improved outcome in pediatric patients with PBL.

TL;DR: A 77-year-old man with a medical history of chronic lymphocytic leukemia who presented with worsening chest pain over 8 weeks underwent minimally invasive aortic valve replacement and mitral repair at his institution, and this is the first reported case of an immunohistochemically documented chronic lymphocytetic leukemia/small lymphocyic lymphoma to involve a cardiac valve.

TL;DR: The findings link caveolin-1 to the power of infiltration and spread, aggressiveness, and differentiation of cancer colon, and this may be happen through E-cadherin-β-catenin complex.

TL;DR: A 50-year-old woman with a history of stage IIB breast cancer and posterolateral right hip pain is described, who shows mildly thickened bone trabeculae and multivacuolated brown fat cells replacing the normal white fat and hematopoietic elements, diagnostic of intraosseous hibernoma.