Showing papers in "Archives of Oral Biology in 2020"

TL;DR: Fusobacterium is present and in higher abundance in oral/head and neck cancer samples when compared to non-cancer samples, suggesting that Fusob bacterium may contribute to oral/ head and neck cancers development.

TL;DR: It is found that oral microbiota dysbiosis and aberrant metabolic pathways were observed in patients with SLE, and may provide suggestive evidences for the diagnosis and treatment of SLE.

TL;DR: MB2 canal prevalence was significantly higher in maxillary first molars and males showed higher odds of having MB2 canal than females, and Geographic region seemed to influence MB2 prevalence outcome.

TL;DR: The data show that NLRP3 mediated pyroptosis has a significant role in diabetes-associated periodontitis and may be the pivot reason of the deteriorated inflammation in this disease, which is ameliorated by metformin treatment.

TL;DR: Findings indicated a critical role of the chronic stress hormone NE in OSCC progression, and inhibition of β2-AR may serve as a potential therapeutic strategy for protecting OSCC patients from chronic stress related deleterious effect.

TL;DR: Rutin could protect hPDLSCs from TNF-α induced damage to osteogenic differentiation in inflammatory environment, and rutin is expected to become a new candidate drug for the treatment of bone defect of periodontitis.

TL;DR: Citronella had a lower cytotoxic effect and a higher action compared to commercial solutions, and led to greater microbial reduction, regardless of the surface of the sample.

TL;DR: In conclusion, the extracts display antimicrobial activity against the tested microorganisms and have the potential to reduce the main substances related to halitosis of oral origin.

TL;DR: Five different surfaces were developed and evaluated the Staphylococcus epidermidis growth in early and late contact to show surface distinct properties influence the growth of S. epiderMidis independent of the based-material.

TL;DR: LncRNA TUG1 accelerates the osteogenic differentiation of human periodontal ligament stem cells by sponging microRNA-222-3p to regulate Smad2/7.

TL;DR: The results indicate that clove, oregano, thyme, and cinnamon essential oils may be added to fluoride-free toothpastes to enhance inhibitory effects against bacteria associated with cavities and periodontal disease.

TL;DR: The effects of TMD management on symptomatic changes of itsComorbidities including the migraine and cervical dysfunction could be determined by onset order of comorbid conditions relative to TMD.

TL;DR: Investigating the biological roles and underlying mechanism of the long non-coding RNA maternally expressed gene 3 (MEG3) on osteogenic differentiation of human dental pulp stem cells revealed that overexpression of MEG3 inhibited hDPSCs osteogenic differentiate via miR-543/SMURF1/RUNX2 regulatory network, which may contribute to the functional regulation and clinical applications of hD PSCs.

TL;DR: Primary hPDLCs responded to irisin treatment with enhanced cell growth, migration, and matrix formation in vitro and promoted osteogenic behaviour of both cell types by enhancement of extracellular matrix formation.

TL;DR: In the SM glands of the diabetic rats, vitamin C supplementation improved the antioxidant system, while vitamin E acted as pro-oxidant.

TL;DR: Patients with periodontitis may not only have inflammation in diseased deep sites, but also present significant hidden subclinical inflammation in their shallow clinically healthy sites.

TL;DR: The findings indicate that V. parvula is not, as previously thought, protective and associated with caries health, and might participate in caries development through interactions with S. mutans.

TL;DR: Overall, fluoride products are able to reduce enamel loss when compared to control, but results must be interpreted with caution.

TL;DR: This systematic review of prevalence studies using cone-beam computed tomographic imaging on second canal morphology in mandibular anterior teeth found that males showed significantly higher odds of having a second canal for both incisors and females showed significantly lower odds.

TL;DR: The gut microbiota underwent dramatic changes after both vancomycin and ampicillin treatment, and the microbiota composition showed a significant difference, but the gut microbiota recovered within four weeks after stopping antibiotics administration, although this recovery was incomplete.

TL;DR: The London Atlas of age estimation performed well in general and good viability in an expert context, with most age groups showing age differences lower than two years of age, however it is necessary that it be applied with caution in certain age groups, especially when the third molar is used as a decision tooth for age estimation.

TL;DR: KetoC exerts a protective function against the oxidative stress in GECs through GPR120-dependent ERK-NRF2-ARE signaling, which regulated the activation of KetoC induced-Nrf2-are signaling.

TL;DR: Archaeal sequences were detected in dental caries and biofilms from surfaces without caries lesions, showing that overall archaeal diversity in the human oral cavity could be currently underestimated and not restricted to methanogens.

TL;DR: Notable activities achieved by essential oils and oil-based irrigants, particularly regarding C. martini and Thymus zygis essential oils, are expected to encourage further research in endodontics.

TL;DR: Among the three methods, the accuracy in the northern Chinese subjects was highest for the Nolla method, and the Willems and Nolla methods were more reliable than the Demirjian method.

TL;DR: The results indicate that P. gingivalis OMVs induced cell death by destroying the barrier system in lung epithelial cells in a dose- and time-dependent manner.

TL;DR: A comprehensive summary of the potential role of bFGF in dental pulp wound healing and regeneration in connection with cell proliferation and differentiation, angiogenesis, and neural differentiation from both in vitro and in vivo studies is given.

TL;DR: Taxifolin successfully reduced apoptosis and improved bone formation in alveolar bone in this experimental periodontitis model.

TL;DR: This study provides the evidence for Rhodiola rosea extract as a novel anti-biofilm agent for clinical use and exhibited a good biocompatibility to human cells.

TL;DR: From a structural and mechanical standpoint, bovine enamel is a suitable alternative to human enamel for in vitro testing of dental products.