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Showing papers in "Canadian Journal of Cardiology in 2004"



Journal Article
TL;DR: Bystander CPR and early first responder defibrillation were significantly associated with increased survival and could be an important first step toward a national cardiac arrest registry comparing the impact of regional differences in patient and system characteristics.

210 citations


Journal Article
TL;DR: Although the association is weak and causal inference cannot be drawn, physical activity explains a small amount of the variance in CVD risk factors during childhood and adolescence, particularly at the extremes.

114 citations


Journal Article
TL;DR: Key recommendations include the following: lifestyle modification should be extended to nonhypertensive individuals who are at risk for developing high blood pressure and stress management should be considered as an intervention in selected individuals.

92 citations


Journal Article
TL;DR: It is suggested that complete surgical resection of primary cardiac tumours prolongs symptom-free survival and is associated with a low recurrence rate and conservative leaflet resection with valve repair of valve myxomas, rather than radical excision and valve replacement, should be strongly considered.

91 citations


Journal Article
TL;DR: This document contains detailed recommendations and supporting evidence on treatment thresholds, target blood pressures and choice of agents for hypertensive patients with or without comorbidities.

85 citations


Journal Article
TL;DR: There is a great burden of heart failure in Canada, increasing significantly with age, and the mortality and readmission rates for this condition are high and exhibit variation among health regions and provinces.

83 citations



Journal Article
TL;DR: In CKD and hemodialysis patients without ACS symptoms, troponin I, at the myocardial infarction cut-off threshold, is unlikely to be falsely elevated and a positive Troponin T helps predict all-cause mortality.

74 citations


Journal Article
TL;DR: Although CHF signs and symptoms did not accurately identify hemodynamic parameters, combined data from history and physical examination provided meaningful information to guide clinical decisions and for prognostication.

73 citations


Journal Article
TL;DR: The rate of hospitalization with AF is increasing in Canada and is more frequent in men than in women across all age groups, and warfarin use was lower than one might expect given its efficacy, with only a small increase in use over time.


Journal Article
TL;DR: A number of modern therapies directed against atherosclerosis also improve the function of the NO synthase pathway, and represent a new front on the war against heart disease.

Journal Article
TL;DR: Hypercholesterolemia has been shown to cause cardiovascular dysfunction due to direct action on membrane fluidity, enzyme activities and cation transporters in the endothelial cells, vascular smooth muscle cells and cardiomyocytes.

Journal Article
TL;DR: The authors concluded that MVP has a much lower prevalence than previously estimated and the prevalence of MVP is similar among different ethnic groups, from a population perspective, and the likelihood of serious cardiovascular complications associated with MVP is low.

Journal Article
TL;DR: Implementation of the new STEMI guidelines has substantial implications for resources, organization and priorities of the Canadian health care system, and it is equally or more important to develop enhanced prehospital care, including the capacity for early recognition, risk assessment, fibrinolytic therapy and/or triage to a tertiary care centre.

Journal Article
TL;DR: In patients with persistent atrial fibrillation, BNP levels are associated with successful cardioversion and maintenance of sinus rhythm two weeks after cardioversion.

Journal Article
TL;DR: Increased communication among health care providers is needed to ensure CR referral, and alternatives to site-based CR are necessary to meet the needs of cardiac patients.

Journal Article
TL;DR: Self-management of warfarin by patients was not significantly better than physician-management in maintaining therapeutic anticoagulation and appeared safe in the present study population.

Journal Article
TL;DR: CCS class was linearly associated with angiographic findings, revascularization rates, mortality and nonfatal myocardial infarction, and support the importance of a four-level grading of symptom severity among angina patients.

Journal Article
TL;DR: This study confirms that the loss of function of cardiac Na+ channels is the basis of the Brugada syndrome clinical phenotype.

Journal Article
TL;DR: The case of a 42-year-old man who presented with ventricular arrhythmia and tricuspid valve regurgitation, and underwent open heart surgery to extract an IVC filter from the right ventricle 12 days after infrarenal IVCfilter placement, is reported.

Journal Article
TL;DR: The prevalence of heart failure in Canadian LTC facilities was 20%, and LTC residents with heart failure were older, more often women, and more functionally impaired and burdened by comorbidity than were participants in heart failure trials.

Journal Article
TL;DR: Outcome differences across socioeconomic strata following AMI may reflect major income- and education-related differences in atherogenic risk profile, which is higher among poorer, less educated patients.

Journal Article
TL;DR: There is a need for practical recruitment assays that have the potential to provide precise and novel insights to distinguish the contribution of chemokines, chemokine receptors and adhesion molecules to the recruitment, survival or proliferation of different leukocyte types in atherosclerotic lesions.

Journal Article
TL;DR: Identification and regulation of this receptor and understanding of signal transduction pathways may lead to new therapies in disease states characterized by endothelial dysfunction, especially in patients with atherosclerosis.

Journal Article
TL;DR: The treatment decision to revascularize the coronary vessels, whether with PCI with or without a stent or with CABG, was consistently associated with significantly better HRQOL at one-year follow-up compared with patients treated with medical therapy.

Journal Article
TL;DR: In selected patients, the transradial approach for rescue PCI is safe and effective and the present findings warrant further study in a prospective, randomized trial.

Journal Article
TL;DR: This study provides a valuable 'snapshot' of cardiac procedure use rates but indicates a clear need for more comprehensive collection of cardiac care data in Canada.

Journal Article
TL;DR: A long-term, double-blind, randomized trial could be required to confirm that the observed increase in vascular distensibility induced by perindopril is related to a mechanism of action other than a reduction in BP.