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Showing papers in "Clinics in Dermatology in 1984"


Journal ArticleDOI
TL;DR: This “natural history” of the virus infection poses a number of fascinating questions: What tissue or tissues harbor the latent infection?

176 citations


Journal ArticleDOI
TL;DR: Physicians, particularly those who perform surgical procedures of the skin, should be familiar with the biologic precepts implicit in the wound healing process, because understanding these principles will ultimately lead to a more rational approach to wound management, which does not run counter to a meticulously conceived script.

158 citations


Journal ArticleDOI
TL;DR: The possible role of electric fields in the migration of epithelial cells that must occur in order to heal wounded skin is considered, and some previously unpublished observations are presented, and the possible relevance of this information to wound healing is speculated on.

151 citations


Journal ArticleDOI
John C. Murray1
TL;DR: Keloids and hypertrophic scars are fibrous growths that result from an abnormal connective tissue response that appear as firm, variably pruritic, or tender growths near the injury site.

129 citations


Journal ArticleDOI
TL;DR: This chapter will review the advantages of secondary intention healing and provide a set of guidelines that will enable one to predict the cosmetic results of wounds allowed to heal by this method.

113 citations


Journal ArticleDOI
TL;DR: It is anticipated that both the mortality and the morbidity will be significantly reduced in infants who are identified early and treated promptly, and the infected infant who is identified soon after delivery has the greatest likelihood of a favorable outcome.

55 citations



Journal ArticleDOI
TL;DR: Eye infection with herpes simplex virus is the single most common cause of corneal blindness in the United States and other industrialized countries and it occurs as often in developing countries.

40 citations



Journal ArticleDOI
TL;DR: Most people seem to think of the skin as a sort of binding or wrapper that keeps the skeleton from falling apart, or out of which, at least in other animals, shoes and various leather articles are made.

26 citations


Journal ArticleDOI
TL;DR: The epidemiology of clinical illnesses has been delineated primarily by periodically examining patients in described populations or from questionnaire surveys and the conclusions drawn are those that are most consistent with the data available.

Journal ArticleDOI
TL;DR: The model was similar to that used by Winter and employed partial thickness wounds in domestic outbred swine and the percentage of the surface re-epithelialized was determined by examining 100 histologic sections from each wound.


Journal ArticleDOI
TL;DR: Since the literature dealing with wound healing from ancient times to the end of the 18th century is entirely clinical, the subject in all of the older accounts is bound up inextricably with wound management.

Journal ArticleDOI
TL;DR: To document the current state-of-the-art in wound care, five prominent dermatologic surgeons are asked to describe their methods of treating wounds and their essentially unedited answers are presented.


Journal ArticleDOI
TL;DR: Experimental animals studies may possess reliable predictive value and serve as useful indicators for further human clinical study and may not always be meaningful to extrapolate such information directly to the human situation because of the anatomic and metabolic differences between laboratory animals and man.

Journal ArticleDOI
TL;DR: Detailed procedures for HSV isolation and typing are described, with brief reviews on methods that have been used in conjunction with virus isolation when cell culture facilities are not available.

Journal ArticleDOI
TL;DR: The purpose of this section is to describe the signs and symptoms that ought to provide the stimulus for the diagnosis of syphilis in its early stages, and the stimulus to perform the tests is provided by the clinical situation at hand.

Journal ArticleDOI
TL;DR: Advances in basic virologic and serologic techniques have contributed much to the authors' understanding of the biologic characteristics of HSV, the mechanisms of latency and reactivation, and potential new therapeutic agents.

Journal ArticleDOI
TL;DR: The interactions among cells, structural and other proteins, and large and small molecules in the dermis is an extremely complex, and largely unknown subject in normal skin, so that these interactions in wounded skin are incapable of complete comprehension at present.

Journal ArticleDOI
TL;DR: It is important that the dermatologist pays attention to the significance of human sexuality, the influence of the skin on eroticism, and the role of dermatologic pathology on human relations in the context of sexual relations.

Journal ArticleDOI
TL;DR: Although it has been demonstrated that cultured epidermal autografts can be successfully transplanted onto partial-thickness wounds, there is very little objective data evaluating their potential effect on the healing process, and this study was undertaken to evaluate objectively.

Journal ArticleDOI
TL;DR: This sector of clinical dermatology stands alongside the two that view psychic activity and the skin in close relationship to each other—the psychosomatic and the somatopsychic.


Journal ArticleDOI
TL;DR: The problem of analyzing the role of the epidermis in wound healing, in which there is damage to the dermis as well as to the epidersmis, becomes difficult, if not insolvable.

Journal ArticleDOI
TL;DR: Dextranomer is a relatively new agent for the cleansing of suppurative wounds and its use in the therapy of exudative lesions was initially conceived by Ult Rothman in the Plastic Surgery Clinic in Malmo, Sweden.

Journal ArticleDOI
TL;DR: It is demonstrated that a higher prevalence of infection with Group A streptococci exists in poor socioeconomic groups and that higher rates of infection exist in hot, steamy environments than in cool climates.

Journal ArticleDOI
TL;DR: The following discussion focuses on selected applications of current methodology to this complex biologic process: wounding, inflammation, cellular proliferation, and remodeling or maturation.

Journal ArticleDOI
TL;DR: The many attempted approaches to therapy of these infections can be divided into several categories: palliation of symptoms, psychosocial support, enhancement of immunity for suppression of recurrences, specific vaccines to prevent primary or recurrent infection, and antiviral agents to prevent or abbreviate virus replication.