Showing papers in "Comparative Biochemistry and Physiology Part C: Comparative Pharmacology in 1984"

TL;DR: The snail Helix pomatia was fed lettuce enriched with zinc, cadmium, lead and copper for 32 days, followed by a feeding period of 40-50 days with uncontaminated lettuce, and the time-dependent distribution of the four metals during loading and unloading was determined in all major organs.

TL;DR: Cardiac and respiratory activity of the shore crab, Carcinus maenas (L.), were disrupted following exposure to heavy metal ions, and death was apparently associated with loss of the osmoregulatory ability.

TL;DR: Daily oral exposure of rats to 30 mg/kg of Aroclor 1254 for 1 month caused deleterious effects on the reproductive process, which were reflected in a decrease in the reproductive potential.

TL;DR: The array of peptides occurring in amphibians from Australia and Papua New Guinea is destined to increase, because several apparently novel peptides have been identified in skin extracts by bioassay and radioimmunoassay.

TL;DR: The ratio of rates of uptake of copper and synthesis of metallothionein was consistent with published values for the copper content of copper-thionein, and tolerance to copper exhibited by fish that continued to be exposed to it was partially lost after 4 weeks depuration.

TL;DR: It is concluded that the biogenic amines and DOPA are ubiquitous in the central nervous system of decapod crustaceans and the presence of NA and Dopa increases the number of presumed neurotransmitter/modulator candidates in the crustacean nervous system.

TL;DR: Results indicate that paraquat toxicity does not result from lipid peroxidation.

TL;DR: Hepatic metallothionein concentrations after 4 weeks of exposure in situ was correlated with the degree of contamination as measured by zinc concentrations (P less than 0.01), but no acclimation to a combination of zinc, copper and cadmium.

TL;DR: Rainbow trout developed elevated hepatic metallothionein concentrations after 4 weeks in a solution containing zinc, copper and cadmium in a fixed ratio of 400:20:1 because the combined toxicity of the metals in the mixture was additive.

TL;DR: The third pair of legs of the primitive New Zealand orthopteran insect, the " weta ", has and innervation and muscle cell distribution exactly similar to that of locusts, but wetas do not jump.

TL;DR: 5-Hydroxytryptamine can stimulate fluid secretion independently of cAMP, and other biogenic amines, including octopamine, adrenalin, dopamine, synephrine and the formamidine chlordimeform were tested for their ability to stimulates fluid secretion.

TL;DR: Carp were exposed to 10 different pollutants with sublethal concentrations at 12, 17 or 22 degrees C, and the effects on the serum cortisol and glucose levels, the amount of liver and muscle glycogen and the concentration of protein and cholesterol in the serum were examined.

TL;DR: The major product in the bile of beta-naphthoflavone-fed trout was an aflatoxicol-M1 glucuronide, whereas the major Product in the control bile was anA flatoxicol glucuronides.

TL;DR: The results obtained in this particular field trial demonstrate that reliance on the measurement of liver MFO parameters alone could lead to false negatives in biological monitoring programs and indicates that the exclusive use of liver tissues to investigate the induction potential of various chemicals should be avoided.

TL;DR: The results suggest that PCB patterns in organs are determined by equilibrium partitioning and components remained mobilizable from organs whose lipid contents increased, in contrast with the idea that PCBs are taken up and stored in lipids under circumstances of increasing lipid content in organs.

TL;DR: Relatively low concentrations of 5-OHTP and NA5-HT were observed in the cerebral ganglia whereas 5-HIAA was not detected and no MAO activity was detected in the central nervous system.

TL;DR: The subcellular distribution of Zn, Cd, Cu and Hg in liver and kidney from a narwhal was determined by ultracentrifugation and gel filtration and Metallothionein was found in these organs in estimated concentrations similar to those present in terrestrial and other marine mammals.

TL;DR: Gamma-aminobutyric acid (GABA) blocked concentration of the pigments in melanophores and erythrophores of intact crabs andOctopamine (OA) blocked black pigment dispersion in intact crabs, but did not affect red pigment disp immersion or concentration.

TL;DR: The effects of waterborne fluoride (NaF) on growth, reproduction and survival in Daphnia magna were studied from subnormal to toxic concentrations in hard reconstituted water.

TL;DR: The data suggest that catecholamines exert their effect on epidermal cell migration via beta 2 adrenergic receptors on the cell surface, a binding site which implicates cAMP in the chain of events.

TL;DR: The turkey poult has been proposed as an attractive animal model for investigation of drug-induced cardiomyopathy and its application in clinical medicine is proposed.

TL;DR: The effects of additions of CuSO4 X 5H2O to final concentrations between 0.0004 and 105 micrograms Cu l-1 on growth, reproduction, survival and haemoglobin content of Daphnia magna were studied in hard reconstituted water and compared to the response in the dilution water without added copper.

TL;DR: The digestive tract contained most (86%) of the 14C remaining in the lobsters, regardless of treatment, and the rate of oxidation of benzo[a]pyrene or 7-ethoxyresorufin in reductase-fortified preparations of hepatopancreas microsomes was the same for corn oil-treated or 3-methylcholanthrene-treated lobsters.

TL;DR: The larva of Sarcophaga peregrina was fed with cadmium (Cd)-containing diet and the distribution of Cd among tissues was determined by separating each organ.

TL;DR: Polyacrylamide gel isoelectric focusing and high-performance liquid chromatography proved to be suitable for gender and species determination when applied to the venoms of A. formidabilis, A. infensus, Atrax robustus and A. versutus.

TL;DR: The biosynthesis and metabolism of 5-hydroxytryptamine (serotonin; 5-HT) in the cestode Hymenolepis diminuta was investigated by High Performance Liquid Chromatography (HPLC) and tissue levels were significantly depressed when the animals were deprived of tryptophan.

TL;DR: Most potential adrenergic compounds did not stimulate lipolysis in swine adipose tissue slices and most of the sympatholytic agents antagonizedlipolysis.

TL;DR: Five peptides were isolated by reverse-phase HPLC from head extracts of the cockroach Leucophaea maderae and indicated that a second peptide, co-eluting with proctolin but refractory to CPY digestion, was responsible for 80% of the biological activity in that fraction.