Showing papers in "Contraception in 1984"

TL;DR: It is concluded that treatment with RU 486 may provide a novel therapy for "menstrual regulation" but the efficacy of the treatment needs to be improved to compete with alternatives such as vacuum aspiration.

TL;DR: It is concluded that some LHRH antagonists produce species specific effects on vascular permeability and spontaneous activity that are peculiar to rats and not observed in mice, rabbits and rhesus monkeys.

TL;DR: In this article, the effects of hormonal contraception on lactation and infant growth were evaluated in a three-centre study in Hungary and Thailand, where women choosing oral contraceptives were randomly assigned to a combined oral contraceptive containing 30 micrograms ethinyl estradiol and 150 microgram of levonorgestrel (N = 86) or a progestin-only preparation containing 75 microgramm dl-norgestrrel (n = 85).

TL;DR: The levonorgestrel-releasing device was associated with significantly fewer bleeding days and significantly increased hemoglobin levels when compared with pre-admission values or the one year values observed among users of the TCu380Ag.

TL;DR: In vitro study showed that the protein disturbed peri-implantation development by blocking the hatching of embryos from the zona pellucida and decreasing the incidence of successful attachment of the blastocyst, and disrupting the development of inner cell mass.

TL;DR: It is concluded that direct injection of THP acts as a potent inhibitor of spermatogenesis resulting in long-term infertility without affecting steroidogenesis, libido, secondary sex characteristics, mating behaviour or serum hormone levels.

TL;DR: The results of the present study indicate that termination of early pregnancy by a medical method, even if self-administered, is an acceptable procedure at least in selected patients.

TL;DR: In this article, the comparative in vitro spermicidal effects of (+)-gossypol, (−)-Gossypols, (−-gossysypols and (+)-Gsophysophols were evaluated on the spermatozoa of human, monkey, rabbit, mouse, rat and hamster.

TL;DR: Total cholesterol, low-density lipoprotein cholesterol and triglyceride levels decreased significantly during NORPLANT use, and the high-density cholesterol showed no change until the twelfth month.

TL;DR: A long-term follow-up study compared development and health of 128 breast-fed children whose mothers had received depot-medroxyprogesterone acetate (depot-MPA) while lactating and 142 control childrenwhose mothers had used mechanical contraceptives or no contraceptives or had undergone sterilization.

TL;DR: Ovarian function is as effectively inhibited by a low-dose triphasic preparation as by a higher, standard-dose OC containing the same steroids, according to these data.

TL;DR: Progestagens may be an alternative contraceptive method in SLE and there were no pregnancies and intermenstrual bleeding led to discontinuation of medication in 30% of patients.

TL;DR: The results are interpreted as suggesting that repeated prolongation of the pill-free period from 7 to 9 days might result in a gradual increase in ovarian activity.

TL;DR: It is demonstrated, with marked contrast, that the implants had less pronounced effects on the blood coagulation system than did the combined pills used in this study.

TL;DR: It is shown that small doses of the drug do not change the hormonal balance of the body, nor do they affect blood pressure, and the drug does not affect semen quality (testicular function), even after a long period of medication.

TL;DR: The differences between the effects of the two preparations on the parameters HDL-cholesterol, % HDL- cholesterol, apoA-I, apOB and the ratio apoB/apoA- I were statistically significant and can be explained by a difference in the intrinsic androgenicity of theTwo progestagens.

TL;DR: The results point to safety of NORPLANT implant use, as regards hepatic functions, with no significant changes in the liver enzymes after NORPLant use.

TL;DR: The effect of a single dose of 150 mg of depo-medroxyprogesterone acetate on pituitary, ovarian and endometrial function was assessed in relation to the peripheral levels of the compound in 8 women.

TL;DR: It is suggested that there is no impairment of fertility in women using norethisterone oenanthate and the return of ovarian activity was studied in 20 women after using the injectable contraceptive for 6 months to 5 years.

TL;DR: The results suggest that the GnRH agonist nafarelin has a potential for contraception by inhibition of ovulation in women.

TL;DR: The metabolism of norgestimate (ORF-10131; 14C-d-13-ethyl-17-acetoxy-18,19-dinor-17 alpha-pregn-4-en-20- yn -3-oxime) was studied in humans and five urinary metabolites were identified by combined gas-liquid chromatography/mass spectrometry.

TL;DR: The data strongly suggest that chronic administration of an LHRH agonist may induce, after cessation of treatment, an overproduction of testicular steroids.

TL;DR: No permanent change in glucose status as a result of oral contraceptive use was found in an analysis for impaired glucose tolerance, diabetes mellitus, diabetic symptoms, or use of oral agents and/or insulin.

TL;DR: Over all categories of termination, women who used the TCu 220C had the lowest one year termination rate, 5.5 per 100, while those who were assigned the Mahua device had the highest one year terminated rate, 13.9 per 100.

TL;DR: The data suggest that low-dose oral contraceptives, by enhancing the rate of conversion of fibrinogen to fibr in by thrombin, increase the risk of venous thrombosis.

TL;DR: There were no significant trends of change in the levels of FSH, LH, E2 and prog during the year, but frequent peaks in E2 concentration were observed and were generally associated with or followed by LH surges.

TL;DR: Results indicate that norethindrone, but not 1-Ng, has a major suppressive effect upon adrenal androgen secretion, and N, O/N and OV contain similar quantities of ethinylestradiol.

TL;DR: In combination with EE, DG seems to be less "anti-oestrogenic" than NORG, as judged from the higher apo-AI and SHBG values after the combination DG + EE compared to those after NORG + EE.

TL;DR: The gentle dilatation by laminaria tents probably induces an endogenous synthesis of prostaglandins causing a softening of the cervix.