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Showing papers in "Electroencephalography and Clinical Neurophysiology in 1968"


Journal ArticleDOI
TL;DR: Responses were obtained when an unpredictable pitch change was presented in an effort to elicit dishabituation and a large positive component with a peak latency of about 300 msec was seen as reflecting a shift of attention associated with the orienting response.

543 citations


Journal ArticleDOI
TL;DR: The MP field distribution was shown to be compatible with its generation by a source of comparable size to the excitable motor cortex and shows a somatotopic distribution for contractions of various muscles similar to that obtained by cortical stimulation.

457 citations


Journal ArticleDOI
TL;DR: The technique allows stereotaxic orientation of micro-electrodes for single unit recording in the intact monkey and provides for vertical penetrations and for minimum loss of time between completion of one penetration and reorientation of the electrode for the subsequent penetration.

264 citations


Journal ArticleDOI
TL;DR: Biochemical analysis for 5-HT of the brains of cats treated with various doses of PCPA confirmed the observations in rats, mice and rabbits; various brain-stem and cortical areas were found to be markedly depleted of (total)5-HT.

190 citations


Journal ArticleDOI
TL;DR: The results suggested that the extent of the reduction was related to the degree of attention focussed on the distracting stimuli as opposed to the stimuli directly relevant to the experimental task.

187 citations


Journal ArticleDOI
TL;DR: The frequency-following response (FFR) differs from an acoustic stimulus of graded onset, and the cochlear microphonic response (CM), in that it has a sharp onset, a latency appropriate to the locus from which it is recorded, an amplitude burst at the onset and a decrement of amplitude over time.

184 citations


Journal ArticleDOI
TL;DR: Examination of the distributions of EEG patterns within each state indicated progressively distinct relationships between state and EEG pattern with maturation, and determination of conceptional age and neurological maturation was based on these relationships.

176 citations


Journal ArticleDOI
TL;DR: Simultaneous recordings were obtained from single pyramidal tract (PT) neurons and from the surface of the motor cortex following stimulation of the surgically isolated PT of barbiturate-anesthetized cats, finding the discharge of the PT cell population was found to contribute negligibly to a cortical surface record, whereas recurrent IPSPs gave rise to a comparatively large amplitude surface negativity.

170 citations


Journal ArticleDOI
TL;DR: It was concluded that the simple technique of sleep deprivation is an effective method of obtaining activation of EEGs in epileptics.

155 citations


Journal ArticleDOI
TL;DR: In this article, the authors performed a clinical and EEG study on two hundred consecutive children with their first convulsion with fever of extracerebral origin and were followed at 3 months, 6 months, 1 year and at yearly intervals thereafter.

132 citations


Journal ArticleDOI
TL;DR: During the periodic presentation of vibratory stimuli at rates faster than 1 stim/10 sec the amplitude of the cortical evoked response of man decreases as a function of time, and this effective information might result from a comparison between information concerning stimulus parameters stored by the CNS and the actual incoming event.

Journal ArticleDOI
TL;DR: The results suggest that PGO waves represent mutually independent responses in the three structures studied to some triggering event in a common pacemaker, and suggests that these potentials are related to some central mechanism of oculomotor-visual integration.

Journal ArticleDOI
TL;DR: This form of epilepsy in a primate may be analogous to reflex, light-triggered epilepsy in man but the topography of light-induced paroxysmal electrical activity observed in the baboon differs from the usually seen in man.

Journal ArticleDOI
David Regan1
TL;DR: Evidence was found that the generators of the two types of response had different spatial distributions or orientations in the brain, and the amplitude of the high frequency evoked responses increased as stimulus frequency was increased near and beyond the point of fusion of perceived flicker.

Journal ArticleDOI
TL;DR: It was concluded that the early scalp deflections usually represent myogenic potentials, while the late components of the responses are a mixture of myogenic and neurogenic potentials.



Journal Article
TL;DR: This syndrome was characterized by restless overactivity, impulsiveness, abrupt clumsy movements, and explosive release of voluntarily inhibited activity and was considered by the authors to be the result of a subacute encephalitis affecting brain stem and basal ganglia.

Journal ArticleDOI
TL;DR: Results suggest that changes in theta frequency are a sub-threshold manifestation of the desynchronizing arousal response.

Journal ArticleDOI
TL;DR: Various properties of both potentials indicate that they reflect post-synaptic responses evoked by recurrent axon collaterals that were investigated in cats under pentobarbital anesthesia.

Journal ArticleDOI
TL;DR: The relationships between the clinical condition, clinical evolution and the nocturnal EEG activity showed, in comatose subjects with typical polygraphic sleep patterns or organized circadian activity, a favourable prognosis, whereasComatoseSubjects with “biphasic” or “monophasic’nocturnal activity, showed a fatal prognosis.


Journal ArticleDOI
TL;DR: The finding that relative reduction of response amplitude duringREM sleep in normals is confined to the eye movement burst phase was related to the concept of phasic inhibition distinct from tonic inhibition during REM sleep.

Journal ArticleDOI
TL;DR: Two conditions in which correlation, not usually present, are found to develop are during electrical seizure discharge in the limbic structures and after a pre-narcotic dose of barbiturates.

Journal ArticleDOI
TL;DR: Cross-correlation analysis of two EMGs led off from the same muscle revealed synchronization of motoneurone discharges during fatigue or intense contraction, and also as an after-effect of poliomyelitis.

Journal ArticleDOI
TL;DR: Evidence of a high “pressure” towards paradoxical (REM) sleep at the expense of Stage II sleep is shown in two healthy men who normally sleep only about 3 h per 24.

Journal ArticleDOI
TL;DR: The development of sleep in kittens and rabbits was studied by means of recording of the EEG, EMG of the posterior neck muscles, respiration as well as observations of gross behavior to show that sleep patterns of rabbits matured much earlier than those of kittens in every respect.

Journal ArticleDOI
TL;DR: Experiments were done in man in an attempt to define more extensively the psychological factors involved in contingent or conative negative variation (CNV) genesis, and CNVs are additive if two anticipations are superimposed in time or if a subject is expecting to perform more than one response of the same kind.

Journal ArticleDOI
TL;DR: The non-specific system was highly depressed by the action of the anesthetics at a time when the auditory input was minimally affected and a close correlation between changes in the level of reticular unit activity and the stage of anesthesia is demonstrated.