Showing papers in "International Journal for Parasitology in 1973"
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TL;DR: Schistosoma mansoni usually have a heptalaminate outer membrane within three hours of penetration and after this time the large vacuoles are replaced by smaller membraneous bodies which presumably contribute to the outer membrane during growth of the schistosomulum.
429 citations
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TL;DR: Guinea pigs acquired resistance to Dermacentor andersoni larvae through acquisition of resistance to immunosuppressant, Methotrexate, and marked infiltration of the infested skin by basophil leucocytes.
193 citations
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TL;DR: Cryopreservation of infective particles of Theileria parva showed that stabilates, tested by rapid thawing and inoculation into ECF-susceptible cattle, remained viable for up to a year at these temperatures.
156 citations
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TL;DR: Groups of ewes which were either lactating, pregnant, non-lactating or unmated were subjected to twice weekly infection with constant numbers of H. contortus and T. colubriformis infective larvae for 8 weeks and showed evidence of diminished immunological responses to infection compared with unmated eWes.
128 citations
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TL;DR: Transformation of Trypanosoma brucei 792G in a monophasic blood lysate medium started from populations of bloodstream trypanosomes containing over 90 per cent intermediate and stumpy forms resulted in optimal growth and morphological transformation.
119 citations
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TL;DR: Results obtained by the use of a number of indirect techniques to detect acetylcholinesterase secretion suggest that the parasitic stages of most, but not all, of the nematodes studied secreted acetylCholinestersterase.
111 citations
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TL;DR: The significance of the fumarate reductase system and its associated phosphorylation in the metabolism of helminths and in the susceptibility of Helminths to anthelmintics is discussed.
103 citations
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TL;DR: A 212-year study of natural snail populations is reported together with simultaneous observations on the transmission of the parasite, finding the importance of seasonal transmission through flowing habitat colonies was borne out by mouse exposures, supplementary snail studies and human incidence data which gave an insight into the dynamics of transmission.
76 citations
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TL;DR: Adult Schistosoma mansoni, which had matured in mice, were rapidly killed in vitro by an immune reaction consisting of three components: monkey antisera to mouse erythrocytes; heat-labile factors which are presumed to be complement; and peptoneactivated monkey peritoneal macrophages.
74 citations
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TL;DR: Nine-week-old Merino lambs inoculated with 85,000 T. colubriformis had increased plasma loss into the gut beginning 10–12 days after infection, coinciding with onset of inappetance, hypoproteinaemia and weight loss, and one infected lamb died, probably due to malnutrition.
56 citations
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TL;DR: The experiments presented indicate that mebendazole inhibits the uptake and/or transport of glucose by Ascaris suum, and this inhibition is followed by a marked decrease in the glycogen content of the ascaris muscle.
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TL;DR: Cattle immunized against Theileria parva (Muguga) showed little resistance to Theilaria lawrencei (Serengeti) stabilate challenge, while cattle immune to T. lawrence i (S Serengeto) were fully resistant to challenge with T. parva.
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TL;DR: Unusually high levels of acetylcholinesterase (AChE) were found in the nematode parasites Trichostrongylus axei, T. colubriformis and T. retortaeformis, and complexing of AChE to globulins did not inhibit the enzymic function of this enzyme.
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TL;DR: Acetylcholinesterase activity in Oesophagostomum radiatum increased markedly during the fourth and early fifth stages of parasitic development and thereafter remained relatively constant in the mature parasites.
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TL;DR: Parasites, completely inhibited by irradiation, did not protect splenectomized calves against challenge infection and behaved immunologically as killed organisms.
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TL;DR: The life cycle of Babesia canis in its arthropod and mammalian hosts, based on extensive personal observation, is described and reviewed.
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TL;DR: The time required for the development of protective immunity to reinfection with T. pisiformis eggs in rabbits, and the stages of larval development affected by it, were examined using in vivo and in vitro systems.
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TL;DR: Changes in the numbers of infective larvae available on pasture and the development of helminth infection in spring-born lambs were studied in an environment with a mild winter and where pastures are grazed throughout the year.
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TL;DR: The evidence suggests that both antigens are produced either from the parasite and are associated closely with erythrocytic components or are produced by digestion of ery throatytic components and represent metabolites of the parasite.
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TL;DR: Study by scanning electron microscopy of heads of Ascaris lumbricoides Linne 1758 and Asaris suum Goeze 1782 showed typical distinctive characteristics between these two species.
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TL;DR: No major ultrastructural reorganisation was observed in the tegument of Raillietina cesticillus during the larval-adult transformation and other (minor) differences in ultrastructure were noted as the parasite developed.
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TL;DR: Immunity was transferred most reliably by cells, especially mesenteric lymph node cells, but most effectively by serum, while multiple immunization of the donors did not markedly increase protection in the recipients.
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TL;DR: The microvilli of the plerocercoid are characterized by a great variation in shape, and the lamellated bodies are especially well developed, which are few in young adults and disappear in mature worms.
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TL;DR: In both types of habitat, infection rates in snails increased with increasing levels of miracidia but decreased as the location of caged snails moved away from the miracidial point of entry, indicating that control measures such as chemotherapy or provision of safe water supplies designed to lower egg output and reduce contamination may not seriously influence transmission.
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TL;DR: Electron micrographs show that polygonal particles occur in the cytoplasm of infected cells; these particles resemble the supposed icosahedral virus of Pirhemocyton, and Immanoplasma is only tentatively included in the group of known and suspected icosahed cytopsized deoxyriboviruses.
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TL;DR: Alkaline phosphatase and disaccharidase activity in the mueosa of lambs killed 18 days after infection is correlated with the dry matter content of the faeces and changes in enzyme activity are thought to arise from damage to mature epithelial cells on the villi.
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TL;DR: It is suggested that the acid hydrolases found on the brush border membrane may be functionally related to extracellular digestion of macromolecules.
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TL;DR: Growth curves, calculated for field populations of B .
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TL;DR: Immunoelectrophoretic analyses of the sera demonstrated that larval metabolic products were more important than breakdown products of dead larvae in stimulating the production of antibodies, and Larval collagenase, which seemed to induce the most significant immune response, was inhibited by homologous antibodies in the serum of a hyperimmunized rabbit.
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TL;DR: Five kinds of malarial antigens were characterized in extracts of infected human placental blood and their storage properties were investigated, finding S-antigens and some normal serum glycoproteins remained in solution after boiling and La1-antigen appeared to aggregate under conditions of low ionic strength.