Showing papers in "Journal of Cardiac Failure in 2004"

TL;DR: Risk stratification of patients with decompensated HF may be accomplished using easily assessed clinical variables using multivariable modeling, and the discriminatory power of the model was substantial for the mortality model but less for the composite endpoint.

TL;DR: Gaps in current knowledge, practice, and research relating to prognostication, symptom management, and supportive care for advanced heart failure are identified and more research is needed to identify the content and technique of communicating prognosis and treatment options.

TL;DR: The Self-Care of Heart Failure Index (SCHFI) as mentioned in this paper is a self-report measure comprised of 15 items rated on a 4-point response scale and divided into three subscales.

TL;DR: Moderate-intensity resistance exercise training in CHF patients produced favorable changes to skeletal muscle strength and endurance, VO(2peak), FBF, and HRV.

TL;DR: The findings suggest that the link between depression and HF may be due to shared pathophysiology, and pathophysiologic pathways and psychosocial issues that are shared between the 2 conditions may represent potential therapeutic targets.

TL;DR: The severity of MR did not provide independent prognostic information in this group recognized to have uniformly high mortality and hemodynamically significant MR is common among patients with advanced CHF.

TL;DR: Plasma MMP-9 concentration correlates with neurohormonal and echocardiographic measures of left ventricular dysfunction after myocardial infarction and Circulating MMP concentrations may provide insights intoleft ventricular remodeling after acute myocardia infarctions.

TL;DR: Although older patients with heart failure have relatively good HRQL in spite of significant functional limitations, they are at risk for worsening HRQL with further decline in functional status, and the importance of treatments aimed at maintaining functional status in older persons with heart Failure is underscored.

TL;DR: Simple interventions can improve ACE inhibitor use and patient outcomes in patients with HF.

TL;DR: Investigation of the mechanisms of anemia in chronic heart failure suggests proinflammatory cytokines are likely to play a significant role by generating the "anemia of chronic illness" that is a hallmark of inflammatory conditions.

TL;DR: Depression is prospectively associated with poorer health status in patients with advanced heart failure and physical and role function, symptom severity, and quality of life are all significantly affected.

TL;DR: Elderly CHF patients are at high risk of death; this risk is magnified in the presence of CKD and anemia.

TL;DR: SPL adverse effects are much more prevalent in the elderly CHF patient population than previously reported and particular caution is mandated in elderly patients with an LVEF <20%, and potassium supplementation should be discontinued.

TL;DR: In patients with CHF, PIIINP levels predict outcome independently of clinical status, hemodynamics and hormonal activation, suggesting that it may reflect more than cardiac extracellular matrix turnover.

TL;DR: A standardized questionnaire provided an approximate 60% concordance in assigning NYHA classification compared to the site assessment with approximately 90% reproducibility, and may be useful to determine NYHA class within the context of clinical trials where blinded conditions are not possible.

TL;DR: Aldosterone directly stimulates hypertrophy in neonatal rat ventricular myocytes and the growth response is dependent on the mineralocorticoid receptor and is associated with activation of ERK, JNK, and PKC-alpha.

TL;DR: The WATCH trial will help define the optimal approach to antithrombotic therapy in the contemporary management of patients with chronic heart failure resulting from left ventricular systolic dysfunction.

TL;DR: In this paper, the authors identify the relationship between three coping styles (active behavioral, active cognitive, and avoidance) and emotional states, and study 84 advanced heart failure patients and used the Dealing with Illness-R Checklist to measure coping and the Profile of Mood States to measure emotional distress.

TL;DR: There is an association between increased lipid peroxidation and both antioxidant status and disease severity in CHF in humans, and these findings support the rationale for intervention trials aiming at exploring beneficial effects of antioxidant micronutrients in this disease.

TL;DR: A heart failure-related hospitalization is a marker of grave prognosis: only one quarter to one third of the patients survives 5 years after admission and age was a strong determinant of mortality and male patients had modestly higher hazard of death than female patients.

TL;DR: Examination of a number of large, contemporary databases shows that in patients with chronic heart failure anemia is an independent prognostic factor and is associated with older age, more severe symptoms and signs, and a greater likelihood of hospitalization.

TL;DR: Big ET-1 andET-1 are strong independent predictors of survival in patients with severe CHF and better for this purpose than natriuretic peptides or their pro-peptides.

TL;DR: Persistently increased cTnT levels (>.020 ng/mL) are predictive of higher rates of death and hospital readmission for decompensated HF.

TL;DR: The literature indicates that the drug has no effect on long-term mortality, but reduces the incidence of hospitalization, and has a positive effect on the clinical status of symptomatic patients.

TL;DR: Neither reductions in muscle oxidative capacity nor capillary density appear to be the cause of exercise limitation in this cohort of patients, and it is hypothesized that the low VO(2peak) observed in CHF patients may be the result of fiber atrophy and possibly impaired activation of oxidative phosphorylation.

TL;DR: It is concluded that subcutaneous administration of BNP (nesiritide) represents a novel and efficacious therapeutic strategy in human congestive heart failure to deliver BNP, a cardiac hormone which possesses unique cardiorenal and neurohumoral properties.

TL;DR: Changing the 6-minute walk test to a time- and distance-based standard would improve the efficiency of the test while retaining the bulk of the prognostic information.

TL;DR: New arrhythmia during an exacerbation of heart failure identifies a high-risk group with higher intrahospital and 60-day morbidity and mortality.

TL;DR: The Acorn Pivotal Trial will formally test the hypothesis that preventing LV remodeling using a passive cardiac support device will favorably impact the untoward natural history of heart failure and thus represents an important departure from all previous medical and device studies that have been reported to date.